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NEUROTROPHIN-4, HUMAN

Description Source Background
Product Name
NEUROTROPHIN-4, HUMAN
CAS No.
146318-03-8
Chemical Name
NEUROTROPHIN-4, HUMAN
Synonyms
NT-4;NTF4;RHNT-4;NT-4 HUMAN;HUMAN NT-4;HUMAN NT-5;NT-5 (HUMAN);NEUROTROPHIN-4;HUMAN NT-4/NT-5;HUMAN NEUROTROPHIN 4
CBNumber
CB0724719
Molecular Formula
C15H24N5O16P3
Formula Weight
623.296243
MOL File
146318-03-8.mol
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NEUROTROPHIN-4, HUMAN Property

storage temp. 
−20°C
form 
lyophilized powder
color 
white to off-white
biological source
human
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Safety

WGK Germany 
3
HS Code 
3504009000
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SRP3129
Product name
NT-4 human
Purity
recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
Packaging
10μG
Price
$369
Updated
2025/07/31
Usbiological
Product number
357727
Product name
NT-4
Packaging
48Tests
Price
$588
Updated
2021/12/16
Usbiological
Product number
357728
Product name
NT-4
Packaging
48Tests
Price
$588
Updated
2021/12/16
Usbiological
Product number
357726
Product name
NT-4
Packaging
48Tests
Price
$588
Updated
2021/12/16
Usbiological
Product number
383886
Product name
NT-4
Packaging
96Tests
Price
$729
Updated
2021/12/16
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NEUROTROPHIN-4, HUMAN Chemical Properties,Usage,Production

Uses

NT-4 is a neurotrophic factor structurally related to b-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).

Biological Activity

NT-4 is a neurotrophic factor structurally related to b-NGF, BDNF, and NT-3. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).

Description

Neurotrophin-4 Human Recombinant produced in E.Coli is a noncovalently linked homodimer, non-glycosylated polypeptide chain containing 2 x 130 amino acids (81-210 amino acids) and having a total molecular mass of 28 kDa.
The NT-4 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

NT-4 is part of the family of neurotrophic factors, neurotrophins, that are in charge for the survival and differentiation of mammalian neurons. NT-4 expression is dominant and less influenced by environmental signals. NT-4 deficient mice shows slight cellular deficits and develop normally to adulthood. NT-4 is a target-derived survival factor for peripheral sensory sympathetic neurons.NT-4 is involved in the proliferation and differentiation of periodontal ligament cells.

NEUROTROPHIN-4, HUMAN Preparation Products And Raw materials

Raw materials

Preparation Products

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NEUROTROPHIN-4, HUMAN Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20)
Fax
0539-6362799(To 20)
Country
China
ProdList
9998
Advantage
58
Shanghai Kanglang Biotechnology Co., Ltd.
Tel
021-61998208 18217752821
Fax
021-37680378
Email
sales@klbio.cn
Country
China
ProdList
9621
Advantage
58
Shanghai Yaji Biological Technology Co., Ltd.
Tel
021-34661275 15301693058
Email
yajikit@163.com
Country
China
ProdList
9921
Advantage
58
Shanghai Yingxin Laboratory Equipment Co., Ltd.
Tel
021-59178156 17002132182
Email
3146474380@qq.com
Country
China
ProdList
10000
Advantage
58
Biolab Reagents
Tel
65279366 18108604356
Email
products@biolabreagent.com
Country
China
ProdList
9868
Advantage
58
Vicbio Biotechnology Co., Ltd.
Tel
400-001-2615 13691409741
Email
info@vicbio.com
Country
China
ProdList
4500
Advantage
58
ACROBiosystems
Tel
13121935750
Email
jiaxin.zhao@acrobiosystems.com
Country
China
ProdList
1360
Advantage
58
Tanmo Quality Inspection Technology Co., Ltd.
Tel
4008-099-669
Email
23419001name@qq.com
Country
CHINA
ProdList
6043
Advantage
58
CUSABIO TECHNOLOGY LLC
Tel
027-87196173
Email
cusabio@163.com
Country
China
ProdList
6066
Advantage
58

146318-03-8, NEUROTROPHIN-4, HUMANRelated Search:


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