NEUROTROPHIN-4, HUMAN
Description Source Background- Product Name
- NEUROTROPHIN-4, HUMAN
- CAS No.
- 146318-03-8
- Chemical Name
- NEUROTROPHIN-4, HUMAN
- Synonyms
- NT-4;NTF4;RHNT-4;NT-4 HUMAN;HUMAN NT-4;HUMAN NT-5;NT-5 (HUMAN);NEUROTROPHIN-4;HUMAN NT-4/NT-5;HUMAN NEUROTROPHIN 4
- CBNumber
- CB0724719
- Molecular Formula
- C15H24N5O16P3
- Formula Weight
- 623.296243
- MOL File
- 146318-03-8.mol
NEUROTROPHIN-4, HUMAN Property
- storage temp.
- −20°C
- form
- lyophilized powder
- color
- white to off-white
- biological source
- human
Safety
- WGK Germany
- 3
- HS Code
- 3504009000
- Storage Class
- 11 - Combustible Solids
N-Bromosuccinimide Price
- Product number
- SRP3129
- Product name
- NT-4 human
- Purity
- recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
- Packaging
- 10μG
- Price
- $369
- Updated
- 2025/07/31
- Product number
- 357727
- Product name
- NT-4
- Packaging
- 48Tests
- Price
- $588
- Updated
- 2021/12/16
- Product number
- 357728
- Product name
- NT-4
- Packaging
- 48Tests
- Price
- $588
- Updated
- 2021/12/16
- Product number
- 357726
- Product name
- NT-4
- Packaging
- 48Tests
- Price
- $588
- Updated
- 2021/12/16
- Product number
- 383886
- Product name
- NT-4
- Packaging
- 96Tests
- Price
- $729
- Updated
- 2021/12/16
NEUROTROPHIN-4, HUMAN Chemical Properties,Usage,Production
Uses
NT-4 is a neurotrophic factor structurally related to b-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).
Biological Activity
NT-4 is a neurotrophic factor structurally related to b-NGF, BDNF, and NT-3. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).
Description
Neurotrophin-4 Human Recombinant produced in E.Coli is a noncovalently linked homodimer, non-glycosylated polypeptide chain containing 2 x 130 amino acids (81-210 amino acids) and having a total molecular mass of 28 kDa.
The NT-4 is purified by proprietary chromatographic techniques.
Source
Escherichia Coli
Background
NT-4 is part of the family of neurotrophic factors, neurotrophins, that are in charge for the survival and differentiation of mammalian neurons. NT-4 expression is dominant and less influenced by environmental signals. NT-4 deficient mice shows slight cellular deficits and develop normally to adulthood. NT-4 is a target-derived survival factor for peripheral sensory sympathetic neurons.NT-4 is involved in the proliferation and differentiation of periodontal ligament cells.
NEUROTROPHIN-4, HUMAN Preparation Products And Raw materials
Raw materials
Preparation Products
NEUROTROPHIN-4, HUMAN Suppliers
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