ChemicalBook > CAS DataBase List > 4-Chloro-3-nitrobenzenesulfonyl chloride
4-Chloro-3-nitrobenzenesulfonyl chloride
- Product Name
- 4-Chloro-3-nitrobenzenesulfonyl chloride
- CAS No.
- 97-08-5
- Chemical Name
- 4-Chloro-3-nitrobenzenesulfonyl chloride
- Synonyms
- Yel;4-CHLORO-3-NITROBENZENESULPHONYL CHLORIDE;4-CHLORO-3-NITROBENZENE-1-SULFONYL CHLORIDE;4-Chloro-3-nitrobenz;YELLOW SULFON CHLORIDE;3-Nitro-4-chlorobenzensulfonyl;4-Chloro-3-nitrobenzenesulfonyl;3-nitro-4-chlorosulfonyl chloride;3-NITRO-4-CHLOROBENZENSULFONYL CHLORIDE;4-chloro-3-nitro-benzenesulfonylchlorid
- CBNumber
- CB0776970
- Molecular Formula
- C6H3Cl2NO4S
- Formula Weight
- 256.06
- MOL File
- 97-08-5.mol
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4-Chloro-3-nitrobenzenesulfonyl chloride Property
- Melting point:
- 59-60 °C (lit.)
- Boiling point:
- 356°C (rough estimate)
- Density
- 1.696 (estimate)
- refractive index
- 1.6000 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Toluene
- form
- Crystalline Powder
- color
- Light brown
- Sensitive
- Moisture Sensitive
- BRN
- 1978600
- CAS DataBase Reference
- 97-08-5(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzenesulfonyl chloride, 4-chloro-3-nitro-(97-08-5)
- EPA Substance Registry System
- Benzenesulfonyl chloride, 4-chloro-3-nitro- (97-08-5)
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Safety
- Hazard Codes
- C
- Risk Statements
- 34-29-14
- Safety Statements
- 26-27-28-36/37/39-45-8-30-22
- RIDADR
- UN 3261 8/PG 2
- WGK Germany
- 3
- Hazard Note
- Corrosive
- TSCA
- Yes
- HazardClass
- 8
- PackingGroup
- II
- HS Code
- 29049090
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H290May be corrosive to metals
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
- Precautionary statements
-
P234Keep only in original container.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P390Absorb spillage to prevent material damage.
P405Store locked up.
P406Store in corrosive resistant/… container with a resistant inner liner.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- C59408
- Product name
- 4-Chloro-3-nitrobenzenesulfonyl chloride
- Purity
- 96%
- Packaging
- 25g
- Price
- $37.6
- Updated
- 2023/06/20
TCI Chemical
- Product number
- C1887
- Product name
- 4-Chloro-3-nitrobenzenesulfonyl Chloride
- Purity
- >96.0%(GC)(T)
- Packaging
- 5g
- Price
- $93
- Updated
- 2025/07/31
TCI Chemical
- Product number
- C1887
- Product name
- 4-Chloro-3-nitrobenzenesulfonyl Chloride
- Purity
- >96.0%(GC)(T)
- Packaging
- 25g
- Price
- $299
- Updated
- 2025/07/31
TRC
- Product number
- C350280
- Product name
- 4-Chloro-3-nitrobenzenesulfonyl chloride
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
TRC
- Product number
- C350280
- Product name
- 4-Chloro-3-nitrobenzenesulfonyl chloride
- Packaging
- 5g
- Price
- $65
- Updated
- 2021/12/16
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4-Chloro-3-nitrobenzenesulfonyl chloride Chemical Properties,Usage,Production
Chemical Properties
LIGHT BROWN CRYSTALLINE POWDER
Uses
4-Chloro-3-nitrobenzenesulfonyl Chloride is used in the synthesis of novel sulfonamide derivatives of tricyclic thieno[2,3-d]pyrimidin-4(3H)-ones which increases melanin synthesis in murine B16 cells.
Uses
4-Chloro-3-nitrobenzenesulfonyl chloride can be used:
- In the preparation of functionalized 1H-indenes via copper-catalyzed arylative cyclization.
- As a precursor in the synthesis of N-arylsulfonyl-3-acylindole arylcarbonyl hydrazone derivatives that show potential nematicidal activity.
- As a key starting material in the synthesis of sulfonamide analogs of ferrostatin-1 (fer-1), which possess good ferroptosis inhibition property.
- In the synthesis of 4-chloro-3-nitrobenzene thiol.
Synthesis
6671-49-4
97-08-5
Synthesis Example 2-2 Synthesis of 4-chloro-3-nitrobenzenesulfonyl chloride: to a reaction vial containing a mixture of 1280 g of potassium 4-chloro-3-nitrobenzenesulfonate, 1150 mL of acetonitrile, 250 mL of sulfoxide, and 30 mL of dimethylacetamide, 1240 mL of phosphinic acid chloride was added dropwise at a slow rate, while controlling the temperature within the reaction system to maintain a temperature of 60°C to 70°C. After the dropwise addition was completed, the reaction mixture was stirred at 73°C for 3 hours. Upon completion of the reaction, the reaction mixture was cooled with water, followed by the slow addition of 400 mL of water. The reaction mixture was poured into 5 L of ice water and the precipitated crystals were separated by filtration, washed with water and dried to give 1060 g of the target product 4-chloro-3-nitrobenzenesulfonyl chloride in 84% yield. The melting point of the product was 55 °C to 56 °C.
References
[1] Patent: US5221750, 1993, A
[2] Patent: US5071994, 1991, A
4-Chloro-3-nitrobenzenesulfonyl chloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Chloro-3-nitrobenzenesulfonyl chloride manufacturers
Shaanxi Dideu Medichem Co. Ltd
- Product
- 4-Chloro-3-nitrobenzenesulfonyl chloride 97-08-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000KG
- Release date
- 2024-08-15
Hebei Zhanyao Biotechnology Co. Ltd
- Product
- 4-Chloro-3-nitrobenzenesulfonyl chloride 97-08-5
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2021-10-19
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- 4-Chloro-3-nitrobenzenesulfonyl chloride 97-08-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
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