ChemicalBook > CAS DataBase List > 1-Octacosanol

1-Octacosanol

Product Name
1-Octacosanol
CAS No.
557-61-9
Chemical Name
1-Octacosanol
Synonyms
Policosanol;OCTACOSANOL;N-OCTACOSANOL;OCTACOSYL ALCOHOL;Cluytyl alcohol;NSC 10770;NSC 57768;Octanosol;Octacosano;ctacosanol
CBNumber
CB0783336
Molecular Formula
C28H58O
Formula Weight
410.76
MOL File
557-61-9.mol
More
Less

1-Octacosanol Property

Melting point:
81-83°C
Boiling point:
200-250°C
Density 
0.8681 (rough estimate)
refractive index 
1.4559 (estimate)
storage temp. 
2-8°C
solubility 
Acetonitrile (Slightly, Heated), Benzene (Slightly, Heated), Chloroform (Slightly, Heated)
pka
15.20±0.10(Predicted)
form 
Crystalline Powder or Flaked Crystals
color 
White
Water Solubility 
<0.1 g/100 mL at 21.5 ºC
Merck 
14,6744
Stability:
Stable. Light-sensitive. Incompatible with strong oxidizing agents.
LogP
13.066 (est)
CAS DataBase Reference
557-61-9(CAS DataBase Reference)
NIST Chemistry Reference
Octacosanol(557-61-9)
EPA Substance Registry System
1-Octacosanol (557-61-9)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
22-24/25-37/39-26
WGK Germany 
-
HS Code 
29051990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
O3379
Product name
1-Octacosanol
Purity
≥99% (GC)
Packaging
100mg
Price
$203
Updated
2024/03/01
Sigma-Aldrich
Product number
O3379
Product name
1-Octacosanol
Purity
≥99% (GC)
Packaging
1g
Price
$832
Updated
2024/03/01
TCI Chemical
Product number
O0199
Product name
1-Octacosanol
Purity
>93.0%(GC)
Packaging
100mg
Price
$111
Updated
2024/03/01
TCI Chemical
Product number
O0199
Product name
1-Octacosanol
Purity
>93.0%(GC)
Packaging
1g
Price
$526
Updated
2024/03/01
Cayman Chemical
Product number
28010
Product name
1-Octacosanol
Packaging
100mg
Price
$54
Updated
2024/03/01
More
Less

1-Octacosanol Chemical Properties,Usage,Production

Chemical Properties

white crystals or powder

Occurrence

Octacosanol is developed from wheat germ, sugar cane, or vegetable waxes.

Uses

A 28-carbon primary fatty alcohol commonly found in the epicuticular waxes of plants. It has shown protective effects against parkonsonism and due to its excellent tolerability and non-toxicity, octacosanol may be a promising agent for PD treatment.

Definition

ChEBI: A long-chain primary fatty alcohol that is octacosane in which a hydrogen attached to one of the terminal carbons is replaced by a hydroxy group.

benefits

1-octacosanol is a straight-chain aliphatic 28-carbon primary fatty alcohol used as a nutritional supplement. This high-molecular-weight organic compound is the main component of a natural product wax extracted from plants. 1-octacosanol is reported to possess cholesterol-lowering effects, antiaggregatory properties, cytoprotective use, and ergogenic properties. It has been studied as a potential therapeutic agent for treating Parkinson's disease.

General Description

White crystalline powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

1-Octacosanol is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.

Fire Hazard

Flash point data for 1-Octacosanol are not available; however, 1-Octacosanol is probably combustible.

Synthesis

To a solution of octacos-11-en-1-ol (400 mg, 0.98 mmol) in THF (40 mL), 10% of Pd on charcoal (50 mg) was added and poured into a Parr reactor. The reduction was carried out at 80 ℃ and 35 bar H2 under stirring for 4 h. Similar results were achieved when the reaction was performed in a special US reactor (21.2 kHz) that works under pressure (Danacamerini – Torino); the reaction was carried out at 40 ℃ and 6 bar H2 for 3 h. In both cases, after filtration on a celite pad and evaporation under vacuum, a crude product was purified by flash chromatography using hexane: ethyl acetate 19: 1 as eluent. 1-Octacosanol was obtained as a white powder (358 mg, 89% yield)[1].

Purification Methods

Recrystallise it from large volumes of Me2CO. Sublime it at 200-250o/1mm instead of distilling it. [Beilstein 2 IV 1318.]

References

[1] Giancarlo Cravotto. “Synthesis of 1-octacosanol and GC-C-IRMS discrimination of samples from different origin.” Natural Product Research 24 5 (2010): 428–39.

1-Octacosanol Preparation Products And Raw materials

Raw materials

Preparation Products

1-Triacontanol
More
Less

1-Octacosanol Suppliers

Americas 1 Australia 1 Canada 5 China 333 Czech Republic 1 Europe 4 Germany 8 India 11 Italy 1 Japan 2 Norway 1 Slovakia 1 South Korea 2 Switzerland 2 The Netherlands 1 United Kingdom 17 United States 53 USA 1 Global 445
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
ApexBio Technology
Tel
--
Fax
--
Email
sales@apexbt.com
Country
United States
ProdList
6251
Advantage
58
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
Scandinavian Formulas
Tel
--
Fax
--
Email
mikep@scandinavianformulas.com
Country
United States
ProdList
1550
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
Xenos Inc.
Tel
--
Fax
--
Email
info@xenosinc.com
Country
United States
ProdList
51
Advantage
58
Farma International
Tel
--
Fax
--
Email
sales@farmainternational.com
Country
United States
ProdList
98
Advantage
58
Marcor Development Corporation (an Azelis Company)
Tel
--
Fax
--
Email
csr@marcordev.com
Country
United States
ProdList
31
Advantage
58
Suzhou Chem Inc.
Tel
--
Fax
--
Email
info@suzhouchem.com
Country
United States
ProdList
9
Advantage
58
Pacific Rainbow International, Inc.
Tel
--
Fax
--
Email
sales@prinutrition.com
Country
United States
ProdList
32
Advantage
58
FCC Products, Inc.
Tel
--
Fax
--
Email
cjkfcc@verizon.net
Country
United States
ProdList
7
Advantage
58
Selleck Chemicals LLC
Tel
--
Fax
--
Email
sales@selleckchem.com
Country
United States
ProdList
1848
Advantage
58
Sabinsa Corporation
Tel
--
Fax
--
Email
info@sabinsa.com
Country
United States
ProdList
16
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
Bell Chem Corp.
Tel
--
Fax
--
Email
uiry@bellchem.com
Country
United States
ProdList
174
Advantage
58
Maypro Industries
Tel
--
Fax
--
Email
maypro@worldnet.att.net
Country
United States
ProdList
76
Advantage
58
Charles Bowman & Company
Tel
--
Fax
--
Country
United States
ProdList
37
Advantage
58
Green Biochemicals US Inc.
Tel
--
Fax
--
Email
info@greenbiochemicals.com
Country
United States
ProdList
26
Advantage
58
NetQem
Tel
--
Fax
--
Email
sales@netqem.us
Country
United States
ProdList
1641
Advantage
38
OChem Incorporation
Tel
--
Fax
--
Email
sales@ocheminc.com
Country
United States
ProdList
6501
Advantage
60
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Charkit Chemical Corporation
Tel
--
Fax
--
Email
sales@charkit.com
Country
United States
ProdList
2993
Advantage
65
Jiangyin Healthway International Trade Co., Ltd
Tel
--
Fax
--
Email
info@healthwaychem.com
Country
United States
ProdList
1006
Advantage
58
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Bosgen Chemical Inc.
Tel
--
Fax
--
Email
sale@chemapi.com
Country
United States
ProdList
609
Advantage
30
Chemstock Inc.
Tel
--
Fax
--
Email
mail@chemstock.com
Country
United States
ProdList
575
Advantage
34
Labseeker Inc
Tel
--
Fax
--
Email
marketing@labseeker.com
Country
United States
ProdList
1495
Advantage
55
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
Sinova Inc.
Tel
--
Fax
--
Email
sales@sinovainc.com
Country
United States
ProdList
4009
Advantage
58
Ivy Fine Chemicals
Tel
--
Fax
--
Email
sales@ivychem.com
Country
United States
ProdList
6493
Advantage
58
Organic Herb Inc. (OHI)
Tel
--
Fax
--
Email
sales@ama4usa.com
Country
United States
ProdList
80
Advantage
30
Garuda International Inc.
Tel
--
Fax
--
Email
garudainfo@garudaint.com
Country
United States
ProdList
8
Advantage
64
Advance Scientific & Chemical
Tel
--
Fax
--
Email
sales@advance-scientific.com
Country
United States
ProdList
6419
Advantage
71
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
American Custom Chemicals Corporation
Tel
--
Fax
--
Email
sales@acccorporation.com
Country
United States
ProdList
6820
Advantage
51
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
Crescent Chemical Co., Inc.
Tel
--
Fax
--
Email
sales@creschem.com
Country
United States
ProdList
4597
Advantage
68
Beta Pharma, Inc.
Tel
--
Fax
--
Email
sales@betapharma.com
Country
United States
ProdList
6226
Advantage
60
More
Less

View Lastest Price from 1-Octacosanol manufacturers

Hebei Longbang Technology Co., Ltd
Product
1-Octacosanol 557-61-9
Price
US $6.00/kg
Min. Order
1kg
Purity
More than 99%
Supply Ability
2000KG/Month
Release date
2024-05-17
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Octacosanol 557-61-9
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-12-10
Baoji Guokang Bio-Technology Co., Ltd.
Product
1-Octacosanol 557-61-9
Price
US $420.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1-20mt
Release date
2021-06-04

557-61-9, 1-Octacosanol Related Search:

1-Hexadecanol 1-Eicosanol Ethyl acetate Levulinic acid Lisinopril Dihydrate Ramipril Enalapril 1-HEXACOSANOL Neosperidin dihydrochalcone D-Pinitol Chrysin 1-Triacontanol flavanol METHYL OCTACOSANOATE NIGERICIN SODIUM SALT HENTRIACONTANOIC ACID POLY(MALEIC ANHYDRIDE-ALT-1-OCTADECENE) TRIACONTYL ACETATE

  • 1-Octacosanol,n-Octacosanol
  • Octacosano
  • 1-Octacosanol SynonyMs: Policosanol
  • 1-Octacosanol Cluytyl alcohol
  • 1-OCTACOSANOL
  • OCTACOSYL ALCOHOL
  • OCTACOSANOL
  • OCTACOSANOL, 1-
  • N-OCTACOSANOL
  • MONTANYL ALCOHOL
  • Twenty-eight alkyl alcohol
  • Nanoactive Policosanol
  • NanoLiposomal Policosanol
  • Octacosanol,95%
  • octacosan-1-ol
  • 1-OCTACOSANOL 93+%
  • Policosanol90-98%
  • Octacosanol10-90%
  • Octacosanol40-70%
  • OCTACOSANOL,POWDER
  • OCTACOSANOL, 1-(P)
  • POLYCOSANOL 60-80%
  • Cluytyl alcohol
  • Policosanol
  • n-Octacosanol 10%~90%
  • 1-Octacosanol,90+%
  • NSC 10770
  • NSC 57768
  • 1-Octacosanol&gt
  • Octanosol
  • Octacosanol(Policosanol)
  • Polyconasol
  • 1-Octacosanol (6CI, 7CI, 8CI, 9CI, ACI)
  • ctacosanol
  • Vegan Policosanol
  • POLICOSANOL(C22-C38)
  • OCTACOSANOL/Montanyl alcohol
  • 1-Octacosanol in isooctane
  • 557-61-9
  • 142583-61-1
  • C28H28O
  • CH3CH227OH
  • C28H58O
  • Saturated Higher Alcohols
  • 1-Alkanols
  • Higher Fatty Acids & Higher Alcohols
  • Fatty Acids
  • Fatty Alcohols
  • Monofunctional & 伪,蠅-Bifunctional Alkanes
  • Monofunctional Alkanes
  • Saturated fatty acids and derivatives
  • Lipids
  • Biochemicals and Reagents
  • BioChemical
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).