ChemicalBook > CAS DataBase List > 2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID

2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID

Product Name
2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID
CAS No.
402-13-1
Chemical Name
2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID
Synonyms
2-aMino-4-(trifluoroMethoxy)benzoic acid;BUTTPARK 24\07-91;Terbinafine Impurity 40;2-Amino-4-Trifluoromethylbenzo;4-(trifluoromethyl)anthranilic acid;2-aMino-4-trifluoroMethylbenaoic acid;2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID;Benzoic acid,2-aMino-4-(trifluoroMethyl)-;2-AMINO-4-TRIFLUOROMETHYLBENZOIC ACID 98%;2-Amino-4-(trifluoromethyl)benzoic Acid >
CBNumber
CB1111066
Molecular Formula
C8H6F3NO2
Formula Weight
205.13
MOL File
402-13-1.mol
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2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID Property

Melting point:
175-176°C
Boiling point:
296.0±40.0 °C(Predicted)
Density 
1.489±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
powder to crystalline
pka
4.43±0.10(Predicted)
color 
White to Amber
Sensitive 
Air Sensitive
InChI
InChI=1S/C8H6F3NO2/c9-8(10,11)4-1-2-5(7(13)14)6(12)3-4/h1-3H,12H2,(H,13,14)
InChIKey
NQTLZJODEOHALT-UHFFFAOYSA-N
SMILES
C(O)(=O)C1=CC=C(C(F)(F)F)C=C1N
CAS DataBase Reference
402-13-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36-36/37/38
Safety Statements 
26-36/37/39
HazardClass 
IRRITANT
HS Code 
29215900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CDS003877
Product name
2-Amino-4-(trifluoromethyl)benzoic acid
Purity
Aldrich<SUP>CPR</SUP>
Packaging
250 mg
Price
$73.1
Updated
2025/07/31
TCI Chemical
Product number
A2175
Product name
2-Amino-4-(trifluoromethyl)benzoic Acid
Purity
>97.0%(HPLC)(T)
Packaging
5g
Price
$84
Updated
2025/07/31
TCI Chemical
Product number
A2175
Product name
2-Amino-4-(trifluoromethyl)benzoic Acid
Purity
>97.0%(HPLC)(T)
Packaging
25g
Price
$334
Updated
2025/07/31
TRC
Product number
A633485
Product name
2-Amino-4-(trifluoromethyl)benzoic Acid
Packaging
500mg
Price
$60
Updated
2021/12/16
TRC
Product number
A633485
Product name
2-Amino-4-(trifluoromethyl)benzoic Acid
Packaging
2.5g
Price
$75
Updated
2021/12/16
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2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID Chemical Properties,Usage,Production

Chemical Properties

Light yellow solid

Synthesis

320-94-5

402-13-1

b) Synthesis of 2-amino-4-trifluoromethylbenzoic acid: 250 g of 2-nitro-4-trifluoromethylbenzoic acid (1.06 mol) was dissolved in 1 liter of ethanol and 7.5 g of 5% palladium/carbon catalyst was added. The reaction mixture was subjected to hydrogenation under hydrogen pressure of 1-2.5 bar. During the reaction, the temperature was gradually increased from 10 °C to 104 °C. After 2 h, the hydrogenation reaction was completed. Subsequently, the catalyst was removed by filtration and the solvent was evaporated under reduced pressure to give 215 g (99% yield) of a light yellow solid product with a melting point of 174-176 °C.

References

[1] Patent: WO2006/108591, 2006, A1. Location in patent: Page/Page column 10; 66
[2] Patent: US2005/124681, 2005, A1. Location in patent: Page/Page column 16
[3] Patent: WO2009/96701, 2009, A2. Location in patent: Page/Page column 28
[4] Journal of Medicinal Chemistry, 1996, vol. 39, # 5, p. 1172 - 1188
[5] Patent: WO2006/125555, 2006, A2. Location in patent: Page/Page column 96

2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID Suppliers

Americas 1 Canada 1 China 139 Europe 3 France 1 Germany 2 India 2 Italy 1 Japan 3 Jordan 1 South Korea 1 Ukraine 1 United Kingdom 12 United States 27 Global 195
Changzhou Yanji Biotechnology Co., Ltd.
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0519-83556355 18015005120
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shikewei397@163.com
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China
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WUXI SHUANGQI TECHNOLOGY CO LTD.
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0510-86529556 18114865355
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1702606491@qq.com
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China
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J & K SCIENTIFIC LTD.
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18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
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96815
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
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021-67121385
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Sales-CN@TCIchemicals.com
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China
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Energy Chemical
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021-021-58432009 400-005-6266
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Wuhan Chemwish Technology Co., Ltd
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86-027-67849912
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86-027-87531808
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sales@chemwish.com
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Capot Chemical Co., Ltd
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+86 (0) 571 85 58 67 18
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0086-571-85864795
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China
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Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
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+86-21-54098501
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+86-21-54096319
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sales@sinch.com.cn
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China
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Changzhou Huanling Chemical Co., Ltd.
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0519-89803565 13776850645
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0519-89803575
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info4@huanlingchem.com
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China
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Shanghai Longsheng chemical Co.,Ltd.
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021-58099652-8005 13585536065
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021-58099609
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bin.wu@shlschem.com
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China
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View Lastest Price from 2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID manufacturers

Honest Joy Holdings Limited
Product
2-Amino-4-(trifluoromethyl)benzoic acid 402-13-1
Price
US $0.00/KG
Min. Order
1KG
Purity
97.6%
Supply Ability
100 tons
Release date
2022-02-20
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID 402-13-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID 402-13-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-12

402-13-1, 2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACIDRelated Search:

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  • Benzoic acid,2-aMino-4-(trifluoroMethyl)-
  • 2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID
  • BUTTPARK 24\07-91
  • 4-(trifluoromethyl)anthranilic acid
  • 2-Amino-4-Trifluoromethylbenzo
  • 2-AMINO-4-TRIFLUOROMETHYLBENZOIC ACID 98%
  • 2-aMino-4-(trifluoroMethoxy)benzoic acid
  • 2-aMino-4-trifluoroMethylbenaoic acid
  • 4-(Trifluoromethyl)anthranilic acid, 4-Carboxy-alpha,alpha,alpha-trifluoro-m-toluidine
  • 2-Amino-4-(trifluoromethyl)benzoic Acid &gt
  • 2-Amino-4-(Trifluoromethyl)Benzoic Acid,>98%
  • 2-Amino-4-(trifluoromethyl)benzoic Acid,4-(Trifluoromethyl)anthranilic Acid
  • Terbinafine Impurity 40
  • 402-13-1
  • Fluorine series
  • Benzoic acid
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts