2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID
- Product Name
- 2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID
- CAS No.
- 83265-53-6
- Chemical Name
- 2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID
- Synonyms
- PO-081211;BUTTPARK 24\07-92;4-Amino-3-carboxybenzotrifluoride;2-Amino-5-trifuloromethylbenzoic acid;2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID;Benzoic acid, 2-amino-5-(trifluoromethyl)-;2-Amino-5-(trifluoromethyl)benzoicacid,95%;2-Amino-5-(trifluoromethyl)benzoic acid 98%;4-Amino-3-carboxybenzotrifluoride, 2-Carboxy-4-(trifluoromethyl)aniline
- CBNumber
- CB4838353
- Molecular Formula
- C8H6F3NO2
- Formula Weight
- 205.1339496
- MOL File
- 83265-53-6.mol
2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID Property
- Melting point:
- 141-146℃
- Boiling point:
- 301.6±42.0 °C(Predicted)
- Density
- 1.489±0.06 g/cm3(Predicted)
- Flash point:
- >110°(230°F)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- Solid
- pka
- 4.51±0.10(Predicted)
- Appearance
- White to light yellow Solid
Safety
- Hazard Codes
- Xi
- Hazard Note
- Irritant
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- A633563
- Product name
- 2-Amino-5-(trifluoromethyl)benzoicAcid
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- PC7503
- Product name
- 2-Amino-5-(trifluoromethyl)benzoicacid
- Purity
- 97%
- Packaging
- 5g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- J98018
- Product name
- 2-Amino-5-(trifluoromethyl)benzoicacid
- Packaging
- 10g
- Price
- $135
- Updated
- 2021/12/16
- Product number
- FA33417
- Product name
- 2-Amino-5-(trifluoromethyl)benzoic acid
- Packaging
- 2g
- Price
- $157.5
- Updated
- 2021/12/16
- Product number
- 4857-3-25
- Product name
- 2-Amino-5-(trifluoromethyl)benzoic acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $195
- Updated
- 2021/12/16
2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID Chemical Properties,Usage,Production
Uses
2-amino-5-(trifluoromethyl)benzoic Acid is a benzoic acid derivative whose molecular structure contains substituents amino and trifluoromethyl at positions 2 and 5. The substance can be used to prepare small molecule inhibitors or anticancer drugs, and is widely used in fields such as chemical or pharmaceutical manufacturing.
Synthesis
1214373-54-2
83265-53-6
Step 2 Synthesis of 2-amino-5-(trifluoromethyl)benzoic acid: 2-nitro-5-(trifluoromethyl)benzoic acid (1.2 g, 4.78 mmol) was suspended in ethanol (10 mL) and 10% Pd/C catalyst (120 mg) was added. The hydrogenation reaction was carried out at room temperature and atmospheric pressure for 1 hour. Upon completion of the reaction, the catalyst was removed by filtration through a diatomaceous earth pad and the filtrate was concentrated to afford 2-amino-5-(trifluoromethyl)benzoic acid (900 mg, 85.2% yield) as a pale white solid. The resulting product could be used in subsequent reactions without further purification.
References
[1] Patent: WO2016/23826, 2016, A1. Location in patent: Page/Page column 52; 53
2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID manufacturers
- Product
- 2-Amino-5-(trifluoromethyl)benzoic acid 83265-53-6
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-31
- Product
- 2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID 83265-53-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-11