3-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID
- Product Name
- 3-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID
- CAS No.
- 125483-00-3
- Chemical Name
- 3-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID
- Synonyms
- 3-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID;3-Amino-4-(trifluoromethyl)benzoicacid98%;Benzoic acid, 3-amino-4-(trifluoromethyl)-;3-Amino-4-(trifluoromethyl)benzoic acid 98%;Benzoic acid, 3-amino-4-(trifluoromethyl)- (9CI);3-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID USP/EP/BP;5-Carboxy-2-(trifluoromethyl)aniline, 2-Amino-4-carboxybenzotrifluoride
- CBNumber
- CB9133668
- Molecular Formula
- C8H6F3NO2
- Formula Weight
- 205.13
- MOL File
- 125483-00-3.mol
3-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID Property
- Melting point:
- 203-205°C
- Boiling point:
- 325.4±42.0 °C(Predicted)
- Density
- 1.489
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- powder
- pka
- 3.85±0.10(Predicted)
- color
- Off white to cream
- CAS DataBase Reference
- 125483-00-3(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- A576670
- Product name
- 3-Amino-4-(trifluoromethyl)benzoicAcid
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 4857-3-34
- Product name
- 3-Amino-4-(trifluoromethyl)benzoic acid
- Purity
- 98%
- Packaging
- 5G
- Price
- $80
- Updated
- 2021/12/16
- Product number
- PC9194
- Product name
- 3-Amino-4-(trifluoromethyl)benzoicacid
- Purity
- 97%
- Packaging
- 10g
- Price
- $90
- Updated
- 2021/12/16
- Product number
- 021433
- Product name
- 3-Amino-4-(trifluoromethyl)benzoic acid
- Purity
- 98%
- Packaging
- 5g
- Price
- $91
- Updated
- 2021/12/16
- Product number
- 021433
- Product name
- 3-Amino-4-(trifluoromethyl)benzoic acid
- Purity
- 98%
- Packaging
- 25g
- Price
- $270
- Updated
- 2021/12/16
3-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID Chemical Properties,Usage,Production
Synthesis
116965-16-3
125483-00-3
A. Synthesis of 3-nitro-4-trifluoromethylbenzoic acid. A mixture of 3-nitro-4-trifluoromethylbenzoic acid (19.5 g, 83 mmol) with 10% Pd/C (4 g) in EtOAc (300 mL) was placed in a pressure vessel and oscillated under an H2 atmosphere at 40 psi. The vessel was repeatedly replenished with H2 until the pressure stabilized at 40 psi. after continuing to oscillate the reaction for 10 minutes, the reaction was terminated by bubbling N2 into the mixture for 30 minutes. The resulting black mixture was filtered through diatomaceous earth and washed with MeOH. The filtrate was concentrated to give 3-amino-4-trifluoromethylbenzoic acid (19.5 g, 98%) in white solid form, which did not require further purification.HPLC analysis: retention time (Rt) = 5.46 min. mass spectrometry (ESI): calculated value of C8H6F3NO2, 205.1; measured value of m/z, 204.3 [M-H]-. 1H NMR (CD3OD): δ 7.51 (s, 1H), 7.45 (d, J = 8.2 Hz, 1H), 7.30 (d, J = 8.0 Hz, 1H), 5.02 (br s, 3H).
References
[1] Patent: US2008/200454, 2008, A1. Location in patent: Page/Page column 48
[2] Liebigs Annalen der Chemie, 1990, # 6, p. 569 - 579
[3] Patent: WO2008/59214, 2008, A1. Location in patent: Page/Page column 150
[4] Patent: WO2015/143653, 2015, A1. Location in patent: Page/Page column 60; 61
[5] Patent: WO2015/148344, 2015, A2. Location in patent: Page/Page column 108
3-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID manufacturers
- Product
- 3-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID 125483-00-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-12