ChemicalBook > CAS DataBase List > 2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID

2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID

Product Name
2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID
CAS No.
83265-53-6
Chemical Name
2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID
Synonyms
PO-081211;BUTTPARK 24\07-92;4-Amino-3-carboxybenzotrifluoride;2-Amino-5-trifuloromethylbenzoic acid;2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID;Benzoic acid, 2-amino-5-(trifluoromethyl)-;2-Amino-5-(trifluoromethyl)benzoicacid,95%;2-Amino-5-(trifluoromethyl)benzoic acid 98%;4-Amino-3-carboxybenzotrifluoride, 2-Carboxy-4-(trifluoromethyl)aniline
CBNumber
CB4838353
Molecular Formula
C8H6F3NO2
Formula Weight
205.1339496
MOL File
83265-53-6.mol
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2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID Property

Melting point:
141-146℃
Boiling point:
301.6±42.0 °C(Predicted)
Density 
1.489±0.06 g/cm3(Predicted)
Flash point:
>110°(230°F)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
Solid
pka
4.51±0.10(Predicted)
Appearance
White to light yellow Solid
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Safety

Hazard Codes 
Xi
Hazard Note 
Irritant
HS Code 
2916399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
A633563
Product name
2-Amino-5-(trifluoromethyl)benzoicAcid
Packaging
10mg
Price
$45
Updated
2021/12/16
Apolloscientific
Product number
PC7503
Product name
2-Amino-5-(trifluoromethyl)benzoicacid
Purity
97%
Packaging
5g
Price
$50
Updated
2021/12/16
AK Scientific
Product number
J98018
Product name
2-Amino-5-(trifluoromethyl)benzoicacid
Packaging
10g
Price
$135
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA33417
Product name
2-Amino-5-(trifluoromethyl)benzoic acid
Packaging
2g
Price
$157.5
Updated
2021/12/16
SynQuest Laboratories
Product number
4857-3-25
Product name
2-Amino-5-(trifluoromethyl)benzoic acid
Purity
98%
Packaging
1g
Price
$195
Updated
2021/12/16
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2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID Chemical Properties,Usage,Production

Uses

2-amino-5-(trifluoromethyl)benzoic Acid is a benzoic acid derivative whose molecular structure contains substituents amino and trifluoromethyl at positions 2 and 5. The substance can be used to prepare small molecule inhibitors or anticancer drugs, and is widely used in fields such as chemical or pharmaceutical manufacturing.

Synthesis

1214373-54-2

83265-53-6

Step 2 Synthesis of 2-amino-5-(trifluoromethyl)benzoic acid: 2-nitro-5-(trifluoromethyl)benzoic acid (1.2 g, 4.78 mmol) was suspended in ethanol (10 mL) and 10% Pd/C catalyst (120 mg) was added. The hydrogenation reaction was carried out at room temperature and atmospheric pressure for 1 hour. Upon completion of the reaction, the catalyst was removed by filtration through a diatomaceous earth pad and the filtrate was concentrated to afford 2-amino-5-(trifluoromethyl)benzoic acid (900 mg, 85.2% yield) as a pale white solid. The resulting product could be used in subsequent reactions without further purification.

References

[1] Patent: WO2016/23826, 2016, A1. Location in patent: Page/Page column 52; 53

2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID Suppliers

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View Lastest Price from 2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID manufacturers

Henan Fengda Chemical Co., Ltd
Product
2-Amino-5-(trifluoromethyl)benzoic acid 83265-53-6
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-31
Career Henan Chemical Co
Product
2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID 83265-53-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-11

83265-53-6, 2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACIDRelated Search:

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  • 2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID
  • BUTTPARK 24\07-92
  • Benzoic acid, 2-amino-5-(trifluoromethyl)-
  • 4-Amino-3-carboxybenzotrifluoride, 2-Carboxy-4-(trifluoromethyl)aniline
  • 2-Amino-5-trifuloromethylbenzoic acid
  • 4-Amino-3-carboxybenzotrifluoride
  • 2-Amino-5-(trifluoromethyl)benzoic acid 98%
  • 2-Amino-5-(trifluoromethyl)benzoicacid,95%
  • PO-081211
  • 83265-53-6
  • Fluorine series
  • Benzoic acid series