ChemicalBook > CAS DataBase List > Febrifugine

Febrifugine

Product Name
Febrifugine
CAS No.
24159-07-7
Chemical Name
Febrifugine
Synonyms
febrifugin;ferifugine;β-dichroine;Febrifugine;Radix Dichroae;(+)-Febrifugine;BETA-Febrifugine;Febrifugine USP/EP/BP;Febrifugine，Isofebrifugine;Febrifugine (6-Desoxyswietenine)
CBNumber
CB11178705
Molecular Formula
C16H19N3O3
Formula Weight
301.34
MOL File
24159-07-7.mol
More
Less

Febrifugine Property

Melting point:
139-140°; mp 154-156°
alpha 
D25 +6° (c = 0.5 in chloroform); D25 +28° (c = 0.5 in ethanol)
Density 
1.39
storage temp. 
2-8°C
solubility 
DMF: 1.5 mg/ml; DMSO: 3.0 mg/ml; Ethanol: 0.1 mg/ml; PBS (pH 7.2): 2.5 mg/ml
form 
A crystalline solid
Boiling point:
508.2±60.0 °C(Predicted)
pka
14.61±0.40(Predicted)
color 
White to off-white
CAS DataBase Reference
24159-07-7
More
Less

Safety

Toxicity
LD50 orally in white mice: 2.5-3.0 mg/kg (Koepfli, 1949)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
14246
Product name
Febrifugine
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
14246
Product name
Febrifugine
Packaging
5mg
Price
$169
Updated
2024/03/01
Usbiological
Product number
300268
Product name
Febrifugine
Packaging
20mg
Price
$665
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0003303
Product name
3-[3-[3(S)-HYDROXYPIPERIDIN-2(R)-YL]-2-OXOPROPYL]-3,4-DIHYDROQUINAZOLIN-4-ONE
Purity
95.00%
Packaging
1G
Price
$3854.55
Updated
2021/12/16
ChemScene
Product number
CS-0022587
Product name
Febrifugine
Packaging
5mg
Price
$336
Updated
2021/12/16
More
Less

Febrifugine Chemical Properties,Usage,Production

Description

Febrifugine is a quinazolinone alkaloid originally isolated from D. febrifuga that has antimalarial activity. It reduces parasitemia and decreases mortality in mice infected with the P. berghei strain NK65 when administered at a dose of 1 mg/kg per day beginning prior to or on the day of infection.

Uses

Febrifugine is a quinazoline alkaloid with significant antimalarial and anticancerous efficacy. Febrifugine is an NRF2 inhibitor, that works with halofuginone for the treatment of chemo- and radio-resistant forms of cancer. Febrifugine analogs also functions as antimalarial, anticancer agents and in the prevention of chicken coccidiosis.

Febrifugine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Febrifugine Suppliers

China 112 Germany 1 United States 7 Global 120
Huzhou ZhanShu Biotechnology Co.,Ltd
Tel
0572-8889530 18167260939
Email
zsubio@163.com
Country
China
ProdList
362
Advantage
58
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Chengdu Herbpurify Co.Ltd.
Tel
18302802153 18981717076
Fax
086-28-85377358
Email
2355253619@qq.com
Country
China
ProdList
1104
Advantage
58
Shanghai Union Resource Chemistry Co., Ltd
Tel
021-50454025 18930054025
Fax
021-50454025
Country
China
ProdList
103
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9648
Advantage
58
Shanghai Aspire Biological Technology Co., Ltd.
Tel
021-61317773
Fax
021-61486878
Email
sales@aspirebio.com
Country
China
ProdList
2880
Advantage
58
Shanghai Yongye Biotechnology Co., Ltd.
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8144
Advantage
55
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
6905
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
Shanghai ChengShao Biological Technology Co., Ltd.
Tel
021-61847300 13341622919
Fax
021-61847300
Email
shcss01@163.com
Country
China
ProdList
4808
Advantage
58
ShangHai Biochempartner Co.,Ltd
Tel
17754423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
Advantage
62
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2886750 13927877953
Fax
0751-2886750
Email
3005811397@qq.com
Country
China
ProdList
13320
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Shanghai Uteam Biotechnology Co., Ltd.
Tel
021-36031160 13311776681
Email
3338195766@QQ.com
Country
China
ProdList
5175
Advantage
55
Shanghai Biological Technology Development Co., Ltd.
Tel
021-69955236-807 13918189704
Fax
021-65211385
Email
chinaruji@chinaruji.com
Country
China
ProdList
5176
Advantage
55
Chengdu Push Bio-Technology Co., Ltd.
Tel
028-85370565-229 18080489829
Email
3004654993@qq.com
Country
China
ProdList
8915
Advantage
60
Chengdu Alfa Biotechnology Co.,Ltd.
Tel
028-85142057, 18030712385
Fax
028-85142057 QQ:3591697873
Email
sales@alfabiotech.com
Country
China
ProdList
1925
Advantage
58
Shanghai Standard Technology Co.,Ltd.
Tel
021-021-57127007-6622-6622 17621252073
Fax
+86 (21) 5132-0077
Email
luzh@nature-standard.com
Country
China
ProdList
3021
Advantage
58
Aikon International Limited
Tel
025-66028182 18112977050
Fax
(3)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
15818
Advantage
58
Shanghai Innovative Reseach Center Of Traditional
Tel
86-21-50801717-301
Fax
86-21-50800509
Email
wangjh@sirc-tcm.sh.cn
Country
China
ProdList
2070
Advantage
58
Foshan DaoQi Biological Co., Ltd.
Tel
18062666947
Fax
18062666959
Email
2355880548@qq.com
Country
China
ProdList
4228
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52693
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2815688 13927872512
Fax
0751-8963795
Email
3007421951@qq.com
Country
China
ProdList
10056
Advantage
58
Nanjing Digger Medical Technology Co. Ltd.
Tel
025-025-51191215 18013836722
Fax
025-51191215
Email
2399235533@qq.com
Country
China
ProdList
4933
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57423
Advantage
58
Nanjing Yuanzhi Biotechnology Co. Ltd.
Tel
15805159960
Email
1211550495@qq.com
Country
China
ProdList
1795
Advantage
58
Chengdu Glip Biotechnology Co., Ltd.
Tel
028-87075086 18030859262
Email
2851503756@qq.com
Country
China
ProdList
1927
Advantage
58
Finetech Industry Limited
Tel
+86-27-87465837 +8618971612321
Fax
86 27 87772287
Email
info@finetechnology-ind.com
Country
China
ProdList
9639
Advantage
58
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
22787
Advantage
58
Wuhan ChemNorm Biotech Co.,Ltd.
Tel
+86-27-8439 4403 18971486879
Fax
+86-27-8439 4403
Email
sales@chemnorm.com
Country
CHINA
ProdList
2935
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58
Zhejiang Lianshuo Biotechnology Co., Ltd.
Tel
18616526224
Email
lianshuo@vip.126.com
Country
China
ProdList
9607
Advantage
58
Chengdu Gupte Biotechnology Co., Ltd.
Tel
13881890404
Fax
028-81711798
Email
2851503757@qq.com
Country
China
ProdList
2283
Advantage
58
Chengdu Alfa Biotechnology Co.,Ltd.
Tel
028-028-85142057 19983342022
Fax
028-85142057
Email
3005359975@qq.com
Country
China
ProdList
1970
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Shanghai jingkang bioengineering co., ltd.
Tel
021-54721350 13524668266
Fax
021-5
Email
2881505714@qq.com
Country
China
ProdList
7872
Advantage
58
Shanghai Kanglang Biotechnology Co., Ltd.
Tel
021-61998208 18217752821
Fax
021-37680378
Email
sales@klbio.cn
Country
China
ProdList
9618
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49476
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29809
Advantage
58
Shanghai Zeye Biotechnology Co., Ltd.
Tel
021-61998551 13122364865
Email
sale1@shzysw.net
Country
China
ProdList
9772
Advantage
58
Absin Bioscience Inc.
Tel
021-38015121 15000105423
Email
wulan@absin.cn
Country
China
ProdList
24731
Advantage
58
PCL - Business, Laboratory Pharmaceutical
Tel
19150123681
Fax
QQ:3008022628
Email
Hu.xinyue@purechemland.com
Country
China
ProdList
3566
Advantage
58
Shanghai Fusheng Industrial Co., LTD
Tel
021-52961053 13524666654
Email
3004902811@qq.com
Country
China
ProdList
9724
Advantage
58
Chengdu PFID reference Technology Co., Ltd
Tel
028-82610909 15882229804
Email
pufeide@foxmail.com
Country
China
ProdList
2335
Advantage
58
Shanghai Sig Biotechnology Co., LTD
Tel
021-57810052 18930344717
Fax
021-57810052
Email
2089316240@qq.com
Country
China
ProdList
9395
Advantage
58
Wuhan ChemNorm co., LTD.
Tel
18971486879
Email
279414929@qq.com
Country
CHINA
ProdList
2925
Advantage
58
ChengDu YiRui Bio-Technology CO., LTD
Tel
182-24028459 18224018291
Fax
QQ137193152
Email
3004072879@qq.com
Country
China
ProdList
1194
Advantage
58
Shanghai Hewu Biotechnology Co., LTD
Tel
021-57886085 17317861055
Email
shhebio@126.com
Country
CHINA
ProdList
7974
Advantage
58
Aktin Chemicals, Inc.
Tel
028-85159085
Email
info@aktinchem.com
Country
China
ProdList
1769
Advantage
58
More
Less

View Lastest Price from Febrifugine manufacturers

Career Henan Chemical Co
Product
Febrifugine 24159-07-7
Price
US $9.80/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
20 tons
Release date
2020-01-09

24159-07-7, FebrifugineRelated Search:

Daurinoline VERATRINE veratramine L-Hyoscyamine Xanthiazone menisdaurin daurisoline 2-[2-(Methylamino)benzoyl]-3,4-dihydro-β-carboline-1(2H)-one VERATRIDINE GROWTH HORMONE, HUMAN Rotundine Matrine Eriocalyxin B KukoaMine B Halofuginone hydrobromide Halofuginone Halofuginone Lactate Febrifugine

  • Febrifugine
  • β-dichroine
  • 3-(3-(3-Hydroxypiperidin-2-yl)-2-oxopropyl)quinazolin-4(3H)-one
  • Febrifugine，Isofebrifugine
  • 3-[3-[(2R,3S)-3-Hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone
  • BETA-Febrifugine
  • febrifugin
  • 4(3H)-Quinazolinone, 3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-
  • Radix Dichroae
  • Febrifugine (6-Desoxyswietenine)
  • Febrifugine USP/EP/BP
  • ferifugine
  • (+)-Febrifugine
  • 24159-07-7