Febrifugine

Product Name: Febrifugine
CAS No.: 24159-07-7
Chemical Name: Febrifugine
Synonyms: febrifugin;ferifugine;β-dichroine;Febrifugine;Radix Dichroae;(+)-Febrifugine;BETA-Febrifugine;Febrifugine USP/EP/BP;Febrifugine，Isofebrifugine;Febrifugine (6-Desoxyswietenine)
CBNumber: CB11178705
Molecular Formula: C16H19N3O3
Formula Weight: 301.34
MOL File: 24159-07-7.mol

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Febrifugine Property

Melting point:: 139-140°; mp 154-156°
alpha: D25 +6° (c = 0.5 in chloroform); D25 +28° (c = 0.5 in ethanol)
Density: 1.39
storage temp.: 2-8°C
solubility: DMF: 1.5 mg/ml; DMSO: 3.0 mg/ml; Ethanol: 0.1 mg/ml; PBS (pH 7.2): 2.5 mg/ml
form: A crystalline solid
Boiling point:: 508.2±60.0 °C(Predicted)
pka: 14.61±0.40(Predicted)
color: White to off-white
CAS DataBase Reference: 24159-07-7

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Safety

Toxicity: LD50 orally in white mice: 2.5-3.0 mg/kg (Koepfli, 1949)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 14246
Product name: Febrifugine
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 14246
Product name: Febrifugine
Packaging: 5mg
Price: $169
Updated: 2024/03/01

Usbiological

Product number: 300268
Product name: Febrifugine
Packaging: 20mg
Price: $665
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CCH0003303
Product name: 3-[3-[3(S)-HYDROXYPIPERIDIN-2(R)-YL]-2-OXOPROPYL]-3,4-DIHYDROQUINAZOLIN-4-ONE
Purity: 95.00%
Packaging: 1G
Price: $3854.55
Updated: 2021/12/16

ChemScene

Product number: CS-0022587
Product name: Febrifugine
Packaging: 5mg
Price: $336
Updated: 2021/12/16

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Febrifugine Chemical Properties,Usage,Production

Description

Febrifugine is a quinazolinone alkaloid originally isolated from D. febrifuga that has antimalarial activity. It reduces parasitemia and decreases mortality in mice infected with the P. berghei strain NK65 when administered at a dose of 1 mg/kg per day beginning prior to or on the day of infection.

Uses

Febrifugine is a quinazoline alkaloid with significant antimalarial and anticancerous efficacy. Febrifugine is an NRF2 inhibitor, that works with halofuginone for the treatment of chemo- and radio-resistant forms of cancer. Febrifugine analogs also functions as antimalarial, anticancer agents and in the prevention of chicken coccidiosis.

Febrifugine Preparation Products And Raw materials

Raw materials

Preparation Products

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Febrifugine Suppliers

China 112 Germany 1 United States 7 Global 120

cfm Oskar Tropitzsch

Tel: --
Fax: --
Country: Germany
ProdList: 1136
Advantage: 62

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View Lastest Price from Febrifugine manufacturers

Career Henan Chemical Co

Product: Febrifugine 24159-07-7
Price: US $9.80/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 20 tons
Release date: 2020-01-09

24159-07-7, FebrifugineRelated Search:

Daurinoline VERATRINE veratramine L-Hyoscyamine Xanthiazone menisdaurin daurisoline 2-[2-(Methylamino)benzoyl]-3,4-dihydro-β-carboline-1(2H)-one VERATRIDINE GROWTH HORMONE, HUMAN Rotundine Matrine Eriocalyxin B KukoaMine B Halofuginone hydrobromide Halofuginone Halofuginone Lactate Febrifugine

Febrifugine

β-dichroine

3-(3-(3-Hydroxypiperidin-2-yl)-2-oxopropyl)quinazolin-4(3H)-one

Febrifugine，Isofebrifugine

3-[3-[(2R,3S)-3-Hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone

BETA-Febrifugine

febrifugin

4(3H)-Quinazolinone, 3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-

Radix Dichroae

Febrifugine (6-Desoxyswietenine)

Febrifugine USP/EP/BP

ferifugine

(+)-Febrifugine

24159-07-7