ChemicalBook > CAS DataBase List > 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one

1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one

Product Name
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one
CAS No.
6969-71-7
Chemical Name
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one
Synonyms
2H-[1,2,4]triazolo[4,3-a]pyridin-3-one;1,2,4-TRIAZOLO-[4,3-A]PYRIDINE-3(2H)-ONE;NSC 68462;Pyridinotriazolone;Triazolo Pyridinone;1,2,4-Triazolo[4,3-a;Pyridine triadiMefon;Trazodone Impurity 15;2,4-Triazolopyridin-3-one;Pyridine threeTriadiMefon
CBNumber
CB1120921
Molecular Formula
C6H5N3O
Formula Weight
135.12
MOL File
6969-71-7.mol
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1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one Property

Melting point:
231°C
Density 
1.51±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
pka
7.86±0.20(Predicted)
form 
Solid
color 
Light Brown to Brown
BRN 
607433
Stability:
Light Sensitive
InChIKey
LJRXNXBFJXXRNQ-UHFFFAOYSA-N
LogP
0.113
CAS DataBase Reference
6969-71-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
736821
Product name
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one
Purity
97%
Packaging
25g
Price
$62.9
Updated
2022/05/15
TCI Chemical
Product number
T1667
Product name
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$46
Updated
2024/03/01
Alfa Aesar
Product number
L18705
Product name
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 98+%
Packaging
5g
Price
$22.65
Updated
2024/03/01
Alfa Aesar
Product number
L18705
Product name
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 98+%
Packaging
25g
Price
$70.65
Updated
2024/03/01
TRC
Product number
T767505
Product name
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one
Packaging
25g
Price
$55
Updated
2021/12/16
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1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one Chemical Properties,Usage,Production

Chemical Properties

Beige Solid

Uses

1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one was used to prepare a congener of Trazodone (T718500) which was found to be a potent and selective inhibitor of synaptosomal uptake of 5-hydroxytryptamine.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 28, p. 1394, 1985 DOI: 10.1021/jm00148a004

1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one Preparation Products And Raw materials

Raw materials

Pyridine

Preparation Products

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1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one Suppliers

Canada 1 China 233 Europe 2 Germany 4 India 45 Italy 1 Japan 4 Slovakia 1 Switzerland 1 The Netherlands 1 United Kingdom 10 United States 39 Global 342
Angelini Fine Chemicals
Tel
--
Fax
--
Email
m.crocetta@angelini.it
Country
Italy
ProdList
61
Advantage
47
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View Lastest Price from 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one manufacturers

Dideu Industries Group Limited
Product
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one 6969-71-7
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-25
Zhuozhou Wenxi import and Export Co., Ltd
Product
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one 6969-71-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one 6969-71-7
Price
US $8.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10MT
Release date
2018-12-21

6969-71-7, 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-oneRelated Search:

Sulfasalazine Furazolidone Sodium Pyrithione Chromium picolinate Triadimefon Zinc pyrithione Trazodone 4-Methylpyridine Pyridine Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate 2-Pyridinecarboxaldehyde Pyridine hydrochloride Pyridine sulfur trioxide 6-BROMO-1,2,4-TRIAZOLO[4,3-A]PYRIDIN-3(2H)-ONE Trazodone hydrochloride 4-HYDROXYPYRIDINE 2-(3-CHLOROPROPYL)-1,2,4-TRIAZOL-[4,3-A]PYRIDINE-3 (2H)-ONE 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl-d6]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one Hydrochloride

  • 1,2,4-TRIAZOLO-[4,3-A]PYRIDINE-3(2H)-ONE
  • 1,2,4-TRIAZOLE(4,3)PYRIDIN-3-(2H)-ONE
  • 1,2,4-TRIAZOL-(4,3-A)-PYRIDINE 3 (2H)-ONE
  • 1,2,4-Triazolopyridin-3-one
  • 3-HYDROXYTRIAZOLO[4,3-A]PYRIDINE
  • 3-HYDROXY-1,2,4-TRIAZOLO[4,3-A]PYRIDINE
  • 1,2,4-Triazole-(4,3-alpha)pyri
  • Trazodone Impurity 15
  • 2,4-Triazolopyridin-3-one
  • Triazolo Pyridinone
  • 2H-[1,2,4]triazolo[4,3-a]pyridin-3-one
  • 1,2,4-Triazole-(4,3-a) Pyridine-3 (2H) - One
  • 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 98+%
  • 1,2,4-Triazolo4,3-aüpyridin-3(2H)-one, 98+%
  • 1,2,4-TRIAZOLO[4,3-A]PYRIDIN-3(2H)-ONE
  • 1,2,4-Triazolo[4,3-a
  • Pyridine triadiMefon
  • 1,2,4-trizolo(4,3a)pyridine-3(2H)-one
  • 1,2,4-Triazol-[4,3-a]-pyridin-3(2H)-one
  • 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one 97%
  • 1,2,4-Triazolo[4,3-<i>a</i>]pyridin-3(2<i>H</i>)-one
  • NSC 68462
  • s-Triazolo[4,3-a]pyridin-3-ol
  • 1,2,4-Triazolo[4,3-a]pyridin-3(H)-one
  • 2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one
  • Pyridine threeTriadiMefon
  • 1,2,4-Triazolo[4,3-a]pyridine-3(2H)
  • Trazodone Triazolopyridinone
  • 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one ISO 9001：2015 REACH
  • [1,2,4] TRIAZOLO [4,3-A] PYRIDIN-3(2H)-ONE ( TPO )
  • 1,2,4-TRIAZOLO-[4,3-α]-PYRIDIN-3(2H)-ONE
  • 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one (9CI, ACI)
  • 1,2,4 triazolo[4,3-a pyridine-3(2H)-Onesodium (TDI)
  • Pyridine Triazolone (trazodone impurity 4)
  • 1,2,4]triazolo[4,3-a]pyridine-3(2H)-Onesodium
  • Pyridinotriazolone
  • 1,2,4]triazolo[4,3-a]pyridin-3-one
  • 6969-71-7
  • 6967-71-7
  • C6H5N3O
  • Heterocycles
  • intermediate for some organic synthesis
  • Fused Ring Systems
  • Pyridines
  • APIs & Intermediate
  • Pyrimidine