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2'-OMe-ibu-G Phosphoramidite

Product Name
2'-OMe-ibu-G Phosphoramidite
CAS No.
150780-67-9
Chemical Name
2'-OMe-ibu-G Phosphoramidite
Synonyms
Cytidine Impurity 13;2’-OMe -dG(iBu) Amidite;N2-iBu-5'-O-DMT-2'-OMe-G-CE;DMT-2'-OMe-G(iBu)-CE-Admite;ibu-2'-OMe-G Phosphoramidite;2'-OMe-ibu-G Phosphoramidite;2'-OMe-ibu-G Phosphoramidite;2'-OMe-G(ibu) Phosphoramidite;2’-OMe-G(ibu) Phosphoramidite;2'-OMe-rG(ibu)Phosphoramidite
CBNumber
CB11871628
Molecular Formula
C45H56N7O9P
Formula Weight
869.94
MOL File
150780-67-9.mol
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2'-OMe-ibu-G Phosphoramidite Property

Melting point:
138 - 140°C
storage temp. 
Inert atmosphere,2-8°C
solubility 
Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly, Sonicated)
form 
powder
pka
9.16±0.20(Predicted)
color 
white to off-white
InChI
InChI=1/C45H56N7O9P/c1-28(2)41(53)49-44-48-40-37(42(54)50-44)47-27-51(40)43-39(57-9)38(61-62(59-25-13-24-46)52(29(3)4)30(5)6)36(60-43)26-58-45(31-14-11-10-12-15-31,32-16-20-34(55-7)21-17-32)33-18-22-35(56-8)23-19-33/h10-12,14-23,27-30,36,38-39,43H,13,25-26H2,1-9H3,(H2,48,49,50,53,54)/t36-,38-,39-,43-,62?/s3
InChIKey
IRRDHRZUOZNWDJ-MLLDKZSOSA-N
SMILES
O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)[C@H](OC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,44,47,r|
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
G211180
Product name
DMT-2′O-Methyl-rG(ib) Phosphoramidite
Purity
configured for PerkinElmer, configured for Polygen
Packaging
1G
Price
$125
Updated
2024/03/01
Sigma-Aldrich
Product number
G211100
Product name
DMT-2′O-Methyl-rG(ib) Phosphoramidite
Purity
≥99% (31P-NMR)
Packaging
100g
Price
$6540
Updated
2024/03/01
Sigma-Aldrich
Product number
G211100
Product name
DMT-2′O-Methyl-rG(ib) Phosphoramidite
Purity
≥99% (31P-NMR)
Packaging
500g
Price
$31680
Updated
2024/03/01
Sigma-Aldrich
Product number
G211150
Product name
DMT-2′O-Methyl-rG(ib) Phosphoramidite
Purity
configured for (?KTA? and OligoPilot?)
Packaging
2g
Price
$172
Updated
2023/06/20
Sigma-Aldrich
Product number
G211180
Product name
DMT-2′O-Methyl-rG(ib) Phosphoramidite
Purity
configured for PerkinElmer, configured for Polygen
Packaging
0.5g
Price
$90.2
Updated
2024/03/01
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2'-OMe-ibu-G Phosphoramidite Chemical Properties,Usage,Production

Chemical Properties

The IUPAC Name is N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

Uses

2''-OMe-ibu-G Phosphoramidite (CAS# 150780-67-9) is used in the synthesis of native-like crosslinked duplex RNA via interstrand crosslinking reaction between vinylpurine on one strand and target cytosine or uracil on the opposite strand.

Definition

2'-OMe-ibu-G Phosphoramidite is a chemically unstable and heat-sensitive nucleoside phosphoramidite that serves as a foundational element in oligonucleotide synthesis. 2'-OMe-RNA CE (β-cyanoethyl) Phosphoramidites are designed to produce synthetic oligonucleotides containing nuclease resistant 2'-O-methyl ribonucleotide linkages. Deprotection, isolation and handling of 2'-O-methyl oligonucleotides are identical to the procedures for oligodeoxynucleotides.

2'-OMe-ibu-G Phosphoramidite Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-OMe-ibu-G Phosphoramidite Suppliers

Austria 1 Canada 1 China 141 India 2 United Kingdom 2 United States 9 Global 156
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View Lastest Price from 2'-OMe-ibu-G Phosphoramidite manufacturers

Hefei Huana Biomedical Technology Co.,Ltd.
Product
N2-iBu-5'-O-DMT-2'-OMe-G-CE 150780-67-9
Price
US $0.00/mg
Min. Order
100mg
Purity
≥98%
Supply Ability
20tons
Release date
2023-03-09
R&D Scientific Inc.
Product
5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine 3'-CE phosphoramidite 150780-67-9
Price
US $60.00/g
Min. Order
1g
Purity
98
Supply Ability
500 Kg
Release date
2024-02-10
SHANGHAI NOVRIBO BIOTECH
Product
2'-OMe-iBu-G CE Phosphoramidite 150780-67-9
Price
US $100.00/kg
Min. Order
0.009999999776482582kg
Purity
99%
Supply Ability
5tons
Release date
2023-03-20

150780-67-9, 2'-OMe-ibu-G PhosphoramiditeRelated Search:

Thiophanate-methyl 1,1-Dimethoxyethane Methyl salicylate Methylene dithiocyanate METSULFURON METHYL Kresoxim-methyl Dimethyldimethoxysilane Cyanoacetic acid Tribenuron methyl Methyl acetate 2'-O-(2-Methoxyethyl)uridine DMT-2'-O-MOE-rU Phosphoramidite 2'-O-MOE-ADENOSINE 2'-O-(2-Methoxyethyl)guanosine Methyl Methyl bromide Parathion-methyl 2'-OMe-ibu-G Phosphoramidite

  • 2’-O-Methy-rG(N-ibu)Phosphoramidite
  • N-blocked-5'-O-DMT-2'-O-Me CED guanosine phosphoramidite
  • 5'-O-(4,4-Dimethoxytrityl)-2'-O-methyl-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
  • 5'-O-DMT-2'-O-Me-rG(N-iBu)-3'-CEDPA
  • 2'-OMe-ibu-G Phosphoramidite
  • 5'-O-DMT-2'-O-Me-G(ibu) phosporamidite
  • DMT-2′O-Methyl-rG(ib) Phosphoramidite
  • ibu-2'-OMe-G Phosphoramidite
  • 2'-OMe-G(iBu)-3'-phosphoramidit
  • 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyroyl-2'-O-methylguanosine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphoramidite
  • 5'-O-DMTr-N2-iBu-2'-O-Me-guanosine-3'-CED phosphoramidite
  • 2'-O-Methyl-N2-Isobutyryl-5'-O-DMT-Guanosine-3'-CE-Phosphoramidite
  • 2'-OMe-G(iBu)-3'-phosphoramidite
  • N2-isobutyryl-5'-O-(4, 4'-Dimethoxytrityl)-2'-O-methyl-Guanosine-3'-CE-Phosphoramidite
  • 2'-O-methylguanosine-ce phosphoramidite for abi
  • Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
  • 2'-OMe-G(ibu) Phosphoramidite
  • DMT-2'-OME-dG(Bz)-CE-Phosphoramidite
  • 5'-Dimethoxytrityl-N-isobutyryl-Guanosine,2'-O-methyl,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
  • DMT-2-O-ME-G-CE Phosphoramidite
  • DMT-2'-O-Me-dG(iBu) Phosphoramidite
  • 5'-O-DMT-2'-OMe-Ibu-Guanosine-CE Phosphoramidite
  • N2-iBu-5'-O-DMT-2'-OMe-G-CE
  • DMT-2’-OMe-G(iBu)-CE Phosphoramidite
  • 5'-O-DMT-2'-OMe-iBu-G Phosphor amidite
  • 5'-O-DMT-2'-OMe-N2-Isobutyryl - Guanosine -3’-Cyanoethyl Phosphoramidite
  • 2'-OMe-N-iBu Guanosine Amidite
  • 2'-OMe-N-dmf Guanosine Amidite
  • 5’-O-(4, 4’-Dimethoxytrityl)-N2-isobutyryl-2’-O-methylguanosine-3’-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
  • DMT-2'-OMe-G(iBu)-CE-Admite
  • Cytidine Impurity 13
  • DMTr-2'-O-Me-rG(iBu)-3'-CE-Phosphoramidite
  • 2’-OMe -dG(iBu) Amidite
  • 5'-ODMT-2'-OMe-N-iBu Guanosine-3'-OCEPA
  • DMT-2'-O-Me-G(iBu)-CE Phosphoramidite
  • 5'-O-(4,4-Dimethoxytrityl)-2'-O-methyl-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
  • 2'-OMe-ibu-G Phosphoramidite
  • 2’-OMe-G(iBu)-3’-phosphoramidite
  • 2’-OMe-G(ibu) Phosphoramidite
  • 2'-OMe-G(iBu)-CE-Phosphoramidite
  • 2'-OMe-iBu-G CE Phosphoramidite
  • (2R,3R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-5,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
  • N2-iBu-2'-OMe-5'-O-DMT-G-3'-CE-Phosphoramidite
  • 2'-OMe-rG(ibu)Phosphoramidite
  • DMT-2'-O-methyl-rG(Ib) Phosphoramidite
  • 5'-O-DMT-N2-isobutyryl-2'-O-methyl-guanosine 3'-CE phosphoramidite
  • 5’-O-(4, 4’-Dimethoxytrityl)-N2-isobutyryl-2’-O-methylguanosine-3’-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
  • 5'-O-DMT-2'-OMe-N2-Isobutyryl - Guanosine -3’-Cyanoethyl Phosphoramidite
  • Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite
  • 2'-OMe-N-dmf Guanosine Amidite
  • 150780-67-9
  • C45H56N7O9P
  • Amidite