ChemicalBook > CAS DataBase List > POLY(N-ISOPROPYL ACRYLAMIDE)

POLY(N-ISOPROPYL ACRYLAMIDE)

Product Name: POLY(N-ISOPROPYL ACRYLAMIDE)
CAS No.: 25189-55-3
Chemical Name: POLY(N-ISOPROPYL ACRYLAMIDE)
Synonyms: PNIPAM;CHEBI:53234;nipam polymer;PNIPAm MW:500;PNIPAm MW:4000;PNIPAM MW:8500;PNIPAm MW:2000;PNIPAAm56KDa-COOH;POLY(N-ISOPROPYL ACRYLAMIDE);N-ISO-PROPYLACRYLAMIDE POLYMER
CBNumber: CB1188228
Molecular Formula: C6H11NO
Formula Weight: 113.15764
MOL File: 25189-55-3.mol

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POLY(N-ISOPROPYL ACRYLAMIDE) Property

Melting point:: 96 °C(lit.)
Density: 1.386 g/cm3
Tg: 130
storage temp.: -20°C
form: powder
color: white to off-white
InChI: InChI=1S/C6H11NO/c1-4-6(8)7-5(2)3/h4-5H,1H2,2-3H3,(H,7,8)
InChIKey: QNILTEGFHQSKFF-UHFFFAOYSA-N
SMILES: C(NC(C)C)(=O)C=C
EPA Substance Registry System: 2-Propenamide, N-(1-methylethyl)-, homopolymer (25189-55-3)

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Safety

WGK Germany: 1

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 900188
Product name: Poly(N-isopropyl acrylamide)
Purity: NHS ester end functionalized, average Mn 5,000
Packaging: 1 g
Price: $381
Updated: 2025/07/31

Sigma-Aldrich

Product number: 806366
Product name: Poly(N-isopropyl acrylamide)
Purity: carboxylic acid, thiol
Packaging: 1 g
Price: $518.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: 535311
Product name: Poly(N-isopropyl acrylamide)
Purity: Mn ~40,000
Packaging: 10g
Price: $847
Updated: 2025/07/31

Sigma-Aldrich

Product number: 900188
Product name: Poly(N-isopropyl acrylamide)
Purity: NHS ester end functionalized, average Mn 5,000
Packaging: 1g
Price: $368
Updated: 2024/03/01

Sigma-Aldrich

Product number: 901422
Product name: Poly(N-isopropylacrylamide)
Purity: average Mn 85,000
Packaging: 10G
Price: $352
Updated: 2023/06/20

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POLY(N-ISOPROPYL ACRYLAMIDE) Chemical Properties,Usage,Production

Chemical Properties

mp 96°C phase transitions at 32°C to insoluble phase

Uses

PolyNIPAM is a stimuli-responsive polymer. The low PDI means that the distribution of chain lengths is narrow which will typically lead to better reproducibility. This polymer for development of thermosensitive coated micro/nano materials including thermoresponsive polymeric drug delivery systems. The carboxylic acid functional group can be used to conjugate a variety of biomolecules to the polymer chain.

Uses

Poly(N-iso-propyl acrylaMide) can be used to form a hydrogel. Aqueous polymer solution undergoes a phase transition from a soluble to an insoluble state when the temperature is raised to ca. 32 °C.

Definition

ChEBI: An acrylic macromolecule, arising from poymerisation of N-isopropylamide.

General Description

Poly(N-isopropylacrylamide) (PNIPAM) is a temperature-responsive polymer used in biomedical research applications. PNIPAM undergoes a reversible, lower critical solution temperature (LCST) phase transition when heated above 32 °C, transitioning from a soluble to an insoluble material. PNIPAM is also frequently crosslinked to yield hydrogels with reversible, thermal shrinking and swelling. Poly(N-isopropylacrylamide) is also readily functionalized and has been used as the hydrophilic block in the synthesis of thermoresponsive, amphiphilic block copolymers. Due to the similarity in temperature between the LCST of PNIPAM and the temperature of the human body, PNIPAM materials have been frequently utilized in tissue engineering and controlled drug delivery research applications.

Solubility in organics

Acetone, THF, water (cold)

POLY(N-ISOPROPYL ACRYLAMIDE) Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from POLY(N-ISOPROPYL ACRYLAMIDE) manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: poly(n-isopropyl acrylamide) 25189-55-3
Price: US $5.90-3.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-06-13

25189-55-3, POLY(N-ISOPROPYL ACRYLAMIDE)Related Search:

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n-(1-methylethyl)-2-propenamidhomopolymer

poly(n-iso-propylacrylamide)(mw20000-25000)

Poly(N-isopropylacrylaMide) Mw 20,000-40,000

Poly(N-isopropylacrylaMide), carboxylic acid terMinated average Mn 10,000

nipam polymer

2-Propenamid, N-(1-methylethyl)-, Homopolymer

2-Propenamide, N-(1-methylethyl)-, homopolymer n-(1-methylethyl)-2-propenamid homopolymer

N-(1-Methylethyl)-2-propenamide homopolymer

Poly(N-isopropylacrylamide),NIPAM polymer, PNIPAM, Polyacrylamide, polyNIPAM

PNIPAM

Poly(N-isopropylacrylamide) Mn 20,000-40,000

Poly(N-isopropylacrylamide) average Mn 30,000

N-ISO-PROPYLACRYLAMIDE POLYMER

POLY(N-ISOPROPYL ACRYLAMIDE)

2-Propenamide,N-(1-methylethyl)-,homopolymer

poly(N-isopropylacrylamide) macromolecule

Poly(N-isopropylacrylamide) (PNiPAM)

Poly(N-isopropylacrylamide) Mn ~40,000

POLY(N-ISOPROPYL ACRYLAMIDE) ISO 9001：2015 REACH

Poly(N-isopropylacrylamide) average Mn 85,000

CHEBI:53234

PNIPAm MW:4000

PNIPAM MW:8500

PNIPAm MW:2000

PNIPAAm56KDa-COOH

PNIPAm MW:500

25189-55-3

CH3C6H11NOnCH3

Acrylamides

Acrylics

Biomaterials

Hydrogels and Crosslinked Polymers

Hydrophilic Polymers

Materials Science

Polymer Science

Polymers