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PROSTAGLANDIN F1ALPHA

Product Name
PROSTAGLANDIN F1ALPHA
CAS No.
745-62-0
Chemical Name
PROSTAGLANDIN F1ALPHA
Synonyms
PGF1;PGF1α;C06475;PGF1ALPHA;protaglandinf1;prostaglandinf1;PROSTAGLANDIN F1A;Prostaglandin F1α;PROSTAGLANDIN F1ALPHA;PROSTAGLANDINS F1ALPHA
CBNumber
CB1237881
Molecular Formula
C20H36O5
Formula Weight
356.5
MOL File
745-62-0.mol
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PROSTAGLANDIN F1ALPHA Property

Melting point:
102.5°C
Boiling point:
409.31°C (rough estimate)
alpha 
+24°(D/24℃)(c=0.87,THF)
Density 
1.0321 (rough estimate)
refractive index 
1.6120 (estimate)
storage temp. 
-20°C
solubility 
DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 2 mg/ml
form 
A crystalline solid
pka
4.78±0.10(Predicted)
BRN 
2704846
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
GY4569700
F 
8-10
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
15010
Product name
Prostaglandin F1α
Purity
≥98%
Packaging
1mg
Price
$55
Updated
2024/03/01
Cayman Chemical
Product number
15010
Product name
Prostaglandin F1α
Purity
≥98%
Packaging
5mg
Price
$243
Updated
2024/03/01
Cayman Chemical
Product number
15010
Product name
Prostaglandin F1α
Purity
≥98%
Packaging
10mg
Price
$404
Updated
2024/03/01
Cayman Chemical
Product number
25900
Product name
Prostaglandin F1α MaxSpec? Standard
Purity
>95%
Packaging
100μg
Price
$94
Updated
2023/06/20
TRC
Product number
P294218
Product name
PGF1alpha(ProstaglandinF1alpha)
Packaging
2.5mg
Price
$105
Updated
2021/12/16
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PROSTAGLANDIN F1ALPHA Chemical Properties,Usage,Production

Description

Prostaglandin F1α (PGF1α) is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF1α and PGF2α (Item Nos. 16010 | 10007221) have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10−11 M. PGF1α binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF2α. It is only half as active as PGF2α in inducing human respiratory smooth muscle contractions in vitro.

Description

Prostaglandin F1α (PGF1α) is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF1α and PGF2α (Item Nos. 16010 | 10007221) have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10−11 M. PGF1α binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF2α. It is only half as active as PGF2α in inducing human respiratory smooth muscle contractions in vitro.

PGF1α MaxSpec® standard is a quantitative grade standard of PGF1α that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This PGF1α MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.

Uses

Prostaglandin F1α (PGF1α) is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF1α and PGF2α have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10?11 M. PGF1α binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF2α. It is only half as active as PGF2α in inducing human respiratory smooth muscle contractions in vitro.

Uses

PGF1alpha (Prostaglandin F1alpha) is a smooth muscle relaxant and a stable metabolite of prostacyclin (PGI2).

Definition

ChEBI: Prostaglandin F1alpha is a prostaglandins Falpha. It has a role as a human metabolite.

General Description

Prostaglandins (PGs) contain prostanoic acid. They are divided as PGA, PGB, PGC, PGD, PGE and PGF groups. They all contain a five-member ring structure differing in their functions. PGF is known to be more soluble in phosphate buffer. PGF1α is a serum eicosanoid.

Biochem/physiol Actions

PGs mediate vasodilation and vasoconstriction.

PROSTAGLANDIN F1ALPHA Preparation Products And Raw materials

Raw materials

Preparation Products

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PROSTAGLANDIN F1ALPHA Suppliers

China 21 Germany 3 Japan 1 Switzerland 1 United Kingdom 3 United States 7 Global 36
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
BIOMOL INTERNATIONAL, LP
Tel
--
Fax
--
Email
info@biomol.com
Country
United States
ProdList
1499
Advantage
77

745-62-0, PROSTAGLANDIN F1ALPHARelated Search:

PROSTAGLANDIN H1 13,14-DIHYDRO-15-KETO-20-ETHYL PROSTAGLANDIN F2ALPHA 15(S)-15-METHYL PROSTAGLANDIN F2ALPHA METHYL ESTER 15-methyl prostaglandin f2alpha,15(S)-15-METHYL PROSTAGLANDIN F2ALPHA (+)-16-M-CHLOROPHENOXY TETRANOR PROSTAGLANDIN F2ALPHA (+)-16-M-CHLOROPHENOXY TETRANOR PROSTAGLANDIN F2ALPHA 13,14-DIHYDRO-15-KETO-20-ETHYL PROSTAGLANDIN F2ALPHA ISOPROPYL ESTER 19(R)-HYDROXY PROSTAGLANDIN F1ALPHA 6-KETO PROSTAGLANDIN F1ALPHA-D4 PROSTAGLANDIN F1ALPHA PGG1 5,6BETA-DIHYDRO PGI2 15-CYCLOHEXYL PENTANOR PROSTAGLANDIN F2ALPHA 15(R)-15-METHYL PROSTAGLANDIN F2ALPHA 11BETA-PROSTAGLANDIN F2ALPHA 99+% 13,14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA ISOPROPYL ESTER 13,14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA,13,14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA 99% 3-METHOXY PROSTAGLANDIN F1ALPHA

  • prostaglandinf1
  • protaglandinf1
  • PROSTAGLANDIN F1A
  • syntheticwhitecrystallinesolid
  • (9α,11α,13e,15s)-9,11,15-trihydroxyprost-13-en-1-oic acid
  • (9a,11a,13E,15S)- 9,11,15-trihydroxy-Prost-13-en-1-oic acid
  • PGF1α, (9α,11α,13E,15S)-9,11,15-Trihydroxyprost-13-en-1-oic acid
  • (13E,15S)-9α,11α,15-Trihydroxyprost-13-en-1-oic acid
  • PGF1
  • PGF1α
  • (13E,15S)-9alpha,11alpha-9,11,15-Trihydroxyprost-13-en-1-oic acid
  • C06475
  • PGF1α (Prostaglandin F1α)
  • PROSTAGLANDIN F1ALPHA
  • PROSTAGLANDINS F1ALPHA
  • PGF1ALPHA
  • 9ALPHA,11ALPHA,15S-TRIHYDROXY-PROST-13E-EN-1-OIC ACID
  • [9ALPHA,11ALPHA,13E,15S]-9,11,15-TRIHYDROXYPROST-13-EN-1-OIC ACID
  • 3,5-dihydroxy-2-(3-hydroxy-1-octenyl)-cyclopentaneheptanoicaci
  • prost-13-en-1-oicacid,9,11,15-trihydroxy-,(9-alpha,11-alpha,13e,15s)
  • Prostaglandin F1 MaxSpecStandard
  • PGF1alpha (Prostaglandin F1alpha)
  • Prostaglandin F1α
  • Prostaglandin F1α MaxSpec? Standard
  • Prost-13-en-1-oic acid, 9,11,15-trihydroxy-, (9α,11α,13E,15S)-
  • Alprostadil Impurity 14
  • Prost-13-en-1-oic acid,9,11,15-trihydroxy-, (9a,11a,13E,15S)-
  • Alprostadil (Prostaglandin E1) Impurity 11
  • PGF1α (Prostaglandin F1α)
  • 745-62-0
  • BioChemical
  • Biochemicals and Reagents
  • Fatty Acids
  • Lipids
  • Prostaglandins