ChemicalBook > CAS DataBase List > BML-259

BML-259

Product Name
BML-259
CAS No.
267654-00-2
Chemical Name
BML-259
Synonyms
BML-259;CAY10554;N-(5-Isopropylthiazol-2-yl)-2-phenylacetamide;Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]-;2-phenyl-N-(5-propan-2-yl-1,3-thiazol-2-yl)acetamide;BML-259,protein,p53,CDK,death,disease,neurotoxicity,cell,Inhibitor,inhibit,Cyclin dependent kinase,Alzheimer's
CBNumber
CB12450947
Molecular Formula
C14H16N2OS
Formula Weight
260.35
MOL File
267654-00-2.mol
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BML-259 Property

Melting point:
150-152℃
storage temp. 
RT
solubility 
Soluble in DMSO (up to 25 mg/ml).
form 
White solid.
color 
white
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SRP0704
Product name
BML-259
Purity
recombinant
Packaging
25mg
Price
$341
Updated
2024/03/01
Alfa Aesar
Product number
J67143
Product name
BML-259, 98%
Packaging
5mg
Price
$139
Updated
2023/06/20
Cayman Chemical
Product number
10010301
Product name
CAY10554
Purity
≥95%
Packaging
5mg
Price
$64
Updated
2024/03/01
Cayman Chemical
Product number
10010301
Product name
CAY10554
Purity
≥95%
Packaging
10mg
Price
$119
Updated
2024/03/01
Cayman Chemical
Product number
10010301
Product name
CAY10554
Purity
≥95%
Packaging
25mg
Price
$280
Updated
2024/03/01
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BML-259 Chemical Properties,Usage,Production

Description

BML-259 (267654-00-2) is a potent inhibitor of Cdk5/p25 (IC50 = 64 nM) and Cdk2 (IC50 = 98nM).1

Definition

ChEBI: 2-phenyl-N-(5-propan-2-yl-2-thiazolyl)acetamide is a member of acetamides.

References

1) Helal et al. (2004) Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer’s disease; Bioorg. Med. Chem. Lett. 14 5521

BML-259 Preparation Products And Raw materials

Raw materials

Preparation Products

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BML-259 Suppliers

China 37 United States 5 Global 42
Shanghai EFE Biological Technology Co., Ltd.
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267654-00-2, BML-259Related Search:

JX401 Imatinib mesylate 1,9-Pyrazoloanthrone LFM-A13 BUTYROLACTONE I PROSTAGLANDIN A2 Flavopiridol Cdk Inhibitor, p35 Palbociclib H-ALA-ASP-ALA-GLN-HIS-ALA-THR-PRO-PRO-LYS-LYS-LYS-ARG-LYS-VAL-GLU-ASP-PRO-LYS-ASP-PHE-OH NU 2058 Roscovitine PD0332991 Isethionate BML-259

  • BML-259
  • CAY10554
  • 2-phenyl-N-(5-propan-2-yl-1,3-thiazol-2-yl)acetamide
  • Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]-
  • BML-259,protein,p53,CDK,death,disease,neurotoxicity,cell,Inhibitor,inhibit,Cyclin dependent kinase,Alzheimer's
  • N-(5-Isopropylthiazol-2-yl)-2-phenylacetamide
  • 267654-00-2