ChemicalBook > CAS DataBase List > N-Boc-cis-4-Hydroxy-L-proline methyl ester

N-Boc-cis-4-Hydroxy-L-proline methyl ester

Product Name
N-Boc-cis-4-Hydroxy-L-proline methyl ester
CAS No.
102195-79-9
Chemical Name
N-Boc-cis-4-Hydroxy-L-proline methyl ester
Synonyms
(2S,4S)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate;1-tert-butyl 2-methyl (2S,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate;BOC-CIS-HYP-OME;cis-Boc-Hyp-OMe;Boc-cis-L-Hyp-OMe;Boc-L-cis-Hyp-OMe;N-Boc-cis-Hyp-Ome;Boc-cis-hyp-ome ,97%;N-Boc-cis-4-Hydroxy-L;BOC-CIS-HYDROXYPROLINE-OME
CBNumber
CB1248508
Molecular Formula
C11H19NO5
Formula Weight
245.27
MOL File
102195-79-9.mol
More
Less

N-Boc-cis-4-Hydroxy-L-proline methyl ester Property

Melting point:
82-86 °C (lit.)
Boiling point:
335.2±42.0 °C(Predicted)
Density 
1.216±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
pka
14.27±0.40(Predicted)
form 
powder to crystal
color 
White to Almost white
Water Solubility 
Insoluble in water.
InChIKey
SVSSZFBZFUSINI-SFYZADRCSA-N
CAS DataBase Reference
102195-79-9(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38-43
Safety Statements 
26-36
WGK Germany 
2
HS Code 
29339900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
654000
Product name
N-Boc-cis-4-hydroxy-L-proline methyl ester
Purity
97%
Packaging
1g
Price
$53.5
Updated
2024/03/01
Sigma-Aldrich
Product number
654000
Product name
N-Boc-cis-4-hydroxy-L-proline methyl ester
Purity
97%
Packaging
5g
Price
$170
Updated
2024/03/01
TCI Chemical
Product number
B3987
Product name
N-(tert-Butoxycarbonyl)-cis-4-hydroxy-L-proline Methyl Ester
Purity
>97.0%(GC)
Packaging
1g
Price
$38
Updated
2024/03/01
TCI Chemical
Product number
B3987
Product name
N-(tert-Butoxycarbonyl)-cis-4-hydroxy-L-proline Methyl Ester
Purity
>97.0%(GC)
Packaging
5g
Price
$114
Updated
2024/03/01
Alfa Aesar
Product number
H27018
Product name
N-Boc-cis-4-hydroxy-L-proline methyl ester, 97%
Packaging
5g
Price
$452
Updated
2023/06/20
More
Less

N-Boc-cis-4-Hydroxy-L-proline methyl ester Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

Used as a local anaesthetic. Used as therapeutic agents. Employed as important intermediates in various areas such as peptide synthesis, polymer chemistry..

Uses

2S,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester oline scaffold.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

N-Boc-cis-4-Hydroxy-L-proline methyl ester Preparation Products And Raw materials

Raw materials

Sodium benzoate Hexane Acetone Sodium chloride Di-tert-butyl dicarbonate Potassium carbonate Triethylamine Chloroform Methanesulfonyl chloride Ethyl acetate Hydrochloric acid Sodium bicarbonate Dichloromethane Methanol Dimethyl sulfoxide L-Hydroxyproline Magnesium sulfate Thionyl chloride PETROLEUM ETHER

Preparation Products

More
Less

N-Boc-cis-4-Hydroxy-L-proline methyl ester Suppliers

Americas 1 Canada 2 China 242 Europe 1 Germany 2 India 8 Japan 3 Switzerland 3 United Kingdom 5 United States 31 Global 298
Shanghai Xinxin Pharmaceutical Technology Co., Ltd.
Tel
13671725141
Email
hickle@yeah.net
Country
China
ProdList
366
Advantage
58
PharmaBlock Sciences (Nanjing), Inc.
Tel
4000255188 4000255188
Fax
025 86918232
Email
sales_china@pharmablock.com
Country
China
ProdList
9786
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12387
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9510
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Shanghai Boc Chemical Co.,Ltd
Tel
021-34975603-808 18721111801
Fax
+86-21-34975602-805
Email
sales@bocpharma.com
Country
China
ProdList
998
Advantage
64
Shanghai Chiral Chemicals Inc.
Tel
021-37285021 13472570865
Fax
86-021-51714507
Email
tym7xi@aliyun.com
Country
China
ProdList
307
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
19951945301
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19185
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Chembon Pharmaceutical Co., Ltd.
Tel
028-84252981
Fax
+86-28-84252965
Email
sales@chembon.com.cn
Country
China
ProdList
814
Advantage
64
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
6791
Advantage
65
SpringPharma Tech Co.,Ltd
Tel
+86-25-68710855, +86-25-68710897
Fax
025-68710856
Email
sales@springpharma.net
Country
China
ProdList
1261
Advantage
62
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
021-51613915-820 13611835272
Fax
021 51613951
Email
mmwang@sunwaypharm.cn
Country
China
ProdList
9734
Advantage
57
Chengdu Pukang Biotechnology Co., Ltd
Tel
028-82550498 19102685862
Fax
086-28-82550468
Email
sales@pu-kang.com
Country
China
ProdList
485
Advantage
58
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Shijiazhuang suchen Chemical Technology Co. LTD
Tel
186-33933494 18032288352
Fax
0311-85310887
Email
1130239@qq.com
Country
China
ProdList
180
Advantage
60
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9478
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 18021050169
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Acesys Pharmatech
Tel
18860950986
Email
tangmanman@zenjipharma.com
Country
China
ProdList
1733
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
EnliPharma Technology Co., Ltd
Tel
0551-66399836 18955197623
Email
sales@enlipharma.com
Country
China
ProdList
1874
Advantage
55
Wuxi Zhangkun Biochemical Technology Co., Ltd.
Tel
+86 0510-85629785
Fax
+86 0510-85625359
Country
China
ProdList
2327
Advantage
58
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Beijing Universal Century Technology Co., Ltd.
Tel
400-8706899
Fax
400-8706899
Email
hysj_bj.com
Country
China
ProdList
3583
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Porse Fine Chemical Co.,LTD
Tel
20-66003216 18666003216
Fax
+86-20-28069063
Email
info@porsefinechemical.com
Country
China
ProdList
2353
Advantage
62
Shanghai GaoLang Chemical Technology Co., Ltd.
Tel
021-57340939 18017297327
Fax
021-37210791
Email
sales@gaolangchemical.com
Country
China
ProdList
892
Advantage
55
Chengdu Firster Pharmaceutical Co., Ltd.
Tel
028-87078428 028-87074958
Fax
8772-8116
Email
chengzhenyong@cdfirster.com
Country
China
ProdList
2677
Advantage
60
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Beijing FYF Chemicals Co., Ltd
Tel
010-57903446 15869909019
Fax
010-57903446
Email
168931144@qq.com
Country
China
ProdList
2994
Advantage
58
Sichuan Ampebiochem Co., Ltd.
Tel
028-65294243
Fax
028-85275169
Email
sales@ampebiochem.com
Country
China
ProdList
1008
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Fax
0731-82251112
Email
viola@huatengsci.com
Country
China
ProdList
5873
Advantage
58
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
Cool Pharm, Ltd
Tel
021-58581007 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9958
Advantage
58
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9484
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Tongling HengYou Biotechnology Co., Ltd.
Tel
021-50426030 13856289449
Fax
021-50426030
Email
2630597085@qq.com
Country
China
ProdList
1889
Advantage
55
Chengdu Chuangkecheng Biological Technology Co., Ltd.
Tel
028-028-0000000 13008177686
Fax
15928581901
Email
sales@ckcbiotech.com
Country
China
ProdList
791
Advantage
55
Quzhou Rundong Chemical (Technology) Co.
Tel
0570-8789886 18892685668
Fax
0570-8789985
Email
info@rundongchemical.com
Country
China
ProdList
3967
Advantage
60
More
Less

View Lastest Price from N-Boc-cis-4-Hydroxy-L-proline methyl ester manufacturers

Henan Fengda Chemical Co., Ltd
Product
(2S,4S)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate 102195-79-9
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-02
Baoji Guokang Healthchem co.,ltd
Product
N-Boc-cis-4-Hydroxy-L-proline methyl ester 102195-79-9
Price
US $1269.80/KG
Min. Order
50g
Purity
99%
Supply Ability
100kg
Release date
2021-06-17
Zhuozhou Wenxi import and Export Co., Ltd
Product
N-Boc-cis-4-Hydroxy-L-proline methyl ester 102195-79-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

102195-79-9, N-Boc-cis-4-Hydroxy-L-proline methyl esterRelated Search:

Tribenuron methyl BOC-L-Proline CHLOROPHOSPHONAZO III Methylparaben Thiophanate-methyl Kresoxim-methyl L-PROLINE-(4-3H(N)) Methyl salicylate D-Proline L-Hydroxyproline cis-4-Hydroxy-L-proline Methyl acrylate N-Boc-cis-4-Hydroxy-L-proline Methyl Methyl bromide N-Boc-trans-4-tosyloxy-L-proline methyl ester (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate N-Boc-trans-4-Hydroxy-L-proline methyl ester

  • (2S,4S)-N-Boc-cis-4-hydroxy-L-proline methyl ester
  • N-Boc-cis-4-hydroxy-L-proline methyl ester, >97.0%(GC)
  • (2S,4S)-N-Boc-4-hydroxyproline methyl ester
  • 1-tert-butyl 2-methyl cis-4-hydroxypyrrolidine-1,2-dicarboxylate
  • cis-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
  • N-T-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER
  • N-ALPHA-T-BUTOXYCARBONYL-CIS-4-HYDROXY-L-PROLINE METHYL ESTER
  • N-Boc-cis-4-hydroxy-L-proline Methyl ester, 97%, 97%
  • Boc-L-cis-4-Hydroxyproline methyl ester
  • 1-tert-butyl 2-methyl (2S,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate
  • N-t-BOC-cis-4-HYDROXYL-L-PROLINE METHYL ESTER
  • cis-N-Boc-4-hydroxy-L-proline Methyl Ester
  • Methyl (4S)-N-Boc-4-hydroxy-L-prolinate
  • O1-tert-Butyl O2-methyl (2S,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate
  • Boc-cis-L-Hyp-OMe
  • cis-N-Boc-4-hydroxy-L-proline Methyl Ester,99%e.e.
  • N-ALPHA-T-BUTOXYCARBONYL-CIS-L-4-HYDROXYPROLINE METHYL ESTER
  • N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER
  • N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ES&
  • METHYL CIS-1-BOC-4-HYDROXY-L-PROLINATE
  • Boc-cis-hydroxyproline methyl ester
  • (2S,4S)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
  • BOC-CIS-HYDROXYPROLINE-OME
  • BOC-CIS-HYP-OME
  • BOC-CIS-L-4-HYDROXYPROLINE METHYL ESTER
  • Boc-cis-4-Hydroxy-L-proline methyl ester
  • Boc-cis-hyp-ome ,97%
  • 1-tert-butyl 2-Methyl (2S)-4-hydroxypyrrolidine-1,2-dicarboxylate
  • N-Boc-cis-4-Hydro×y-L-proline Methyl ester
  • (2S,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester
  • <i>N</i>-Boc-<i>cis</i>-4-hydroxy-L-proline Methyl ester
  • N-Boc-<i>cis</i>-4-hydroxy-L-proline Methyl ester
  • cis-Boc-Hyp-OMe
  • N-(tert-Butoxycarbonyl)-cis-4-hydroxy-L-proline Methyl Ester
  • 1,2-Pyrrolidinedicarboxylicacid, 4-hydroxy-, 1-(1,1-diMethylethyl) 2-Methyl ester, (2S,4S)-
  • N-Boc-cis-4-hydroxy-L-proline methyl, 97%
  • Boc-L-cis-Hyp-OMe
  • N-Boc-cis-Hyp-Ome
  • 1-o-tert-butyl 2-o-methyl (2s,4s)-4-hydroxypyrrolidine-1,2-dicarboxylate
  • N-(tert-Butoxycarbonyl)-cis-4-hydroxy-L-prolineMethylEster&gt
  • N-Boc-cis-4-Hydroxy-L
  • (2S,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl 2-Methyl Ester
  • N-Boc-cis-4-Hydroxy-L-proline methyl ester USP/EP/BP
  • (2S,4S)-1-tert-Butoxycarbonyl-4-hydroxypyrrolidine-2-carboxylic acid methyl ester
  • 2-Methyl 1-(2-methyl-2-propanyl) (2S,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate
  • 102195-79-9
  • Unnatural Amino Acid Derivatives
  • Specialty Synthesis
  • Peptide Synthesis
  • Proline Derivatives
  • Heterocycles
  • Peptide Synthesis
  • Proline Derivatives
  • Unnatural Amino Acid Derivatives