ChemicalBook > CAS DataBase List > N-Boc-cis-4-Hydroxy-L-proline methyl ester

N-Boc-cis-4-Hydroxy-L-proline methyl ester

Product Name: N-Boc-cis-4-Hydroxy-L-proline methyl ester
CAS No.: 102195-79-9
Chemical Name: N-Boc-cis-4-Hydroxy-L-proline methyl ester
Synonyms: (2S,4S)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate;1-tert-butyl 2-methyl (2S,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate;BOC-CIS-HYP-OME;cis-Boc-Hyp-OMe;Boc-cis-L-Hyp-OMe;Boc-L-cis-Hyp-OMe;N-Boc-cis-Hyp-Ome;Boc-cis-hyp-ome ,97%;N-Boc-cis-4-Hydroxy-L;BOC-CIS-HYDROXYPROLINE-OME
CBNumber: CB1248508
Molecular Formula: C11H19NO5
Formula Weight: 245.27
MOL File: 102195-79-9.mol

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N-Boc-cis-4-Hydroxy-L-proline methyl ester Property

Melting point:: 82-86 °C (lit.)
Boiling point:: 335.2±42.0 °C(Predicted)
Density: 1.216±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
pka: 14.27±0.40(Predicted)
form: powder to crystal
color: White to Almost white
optical activity: -63.6200°(C=1.011g/100ml ETOH)
Water Solubility: Insoluble in water.
InChI: InChI=1S/C11H19NO5/c1-11(2,3)17-10(15)12-6-7(13)5-8(12)9(14)16-4/h7-8,13H,5-6H2,1-4H3/t7-,8-/m0/s1
InChIKey: SVSSZFBZFUSINI-SFYZADRCSA-N
SMILES: N1(C(OC(C)(C)C)=O)C[C@@H](O)C[C@H]1C(OC)=O
CAS DataBase Reference: 102195-79-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38-43
Safety Statements: 26-36
WGK Germany: 2
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 654000
Product name: N-Boc-cis-4-hydroxy-L-proline methyl ester
Purity: 97%
Packaging: 1g
Price: $55.1
Updated: 2025/07/31

Sigma-Aldrich

Product number: 654000
Product name: N-Boc-cis-4-hydroxy-L-proline methyl ester
Purity: 97%
Packaging: 5g
Price: $175
Updated: 2025/07/31

TCI Chemical

Product number: B3987
Product name: N-(tert-Butoxycarbonyl)-cis-4-hydroxy-L-proline Methyl Ester
Purity: >97.0%(GC)
Packaging: 1g
Price: $34
Updated: 2025/07/31

TCI Chemical

Product number: B3987
Product name: N-(tert-Butoxycarbonyl)-cis-4-hydroxy-L-proline Methyl Ester
Purity: >97.0%(GC)
Packaging: 5g
Price: $103
Updated: 2025/07/31

TRC

Product number: H656565
Product name: (2S,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylicAcid1-tert-ButylEster2-MethylEster
Packaging: 1g
Price: $140
Updated: 2021/12/16

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N-Boc-cis-4-Hydroxy-L-proline methyl ester Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

Used as a local anaesthetic. Used as therapeutic agents. Employed as important intermediates in various areas such as peptide synthesis, polymer chemistry..

Uses

2S,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester oline scaffold.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

IC 50

Non-cleavable Linker

N-Boc-cis-4-Hydroxy-L-proline methyl ester Preparation Products And Raw materials

Raw materials

Sodium benzoate Hexane Acetone Sodium chloride Di-tert-butyl dicarbonate Potassium carbonate Triethylamine Chloroform Methanesulfonyl chloride Ethyl acetate Hydrochloric acid Sodium bicarbonate Dichloromethane Methanol Dimethyl sulfoxide L-Hydroxyproline Magnesium sulfate Thionyl chloride PETROLEUM ETHER

Preparation Products

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View Lastest Price from N-Boc-cis-4-Hydroxy-L-proline methyl ester manufacturers

Henan Fengda Chemical Co., Ltd

Product: (2S,4S)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate 102195-79-9
Price: US $200.00-1.00/KG
Min. Order: 1KG
Purity: 99%, 99.5% Sublimated
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-01-02

Baoji Guokang Healthchem co.,ltd

Product: N-Boc-cis-4-Hydroxy-L-proline methyl ester 102195-79-9
Price: US $1269.80/KG
Min. Order: 50g
Purity: 99%
Supply Ability: 100kg
Release date: 2021-06-17

Zhuozhou Wenxi import and Export Co., Ltd

Product: N-Boc-cis-4-Hydroxy-L-proline methyl ester 102195-79-9
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

102195-79-9, N-Boc-cis-4-Hydroxy-L-proline methyl esterRelated Search:

Tribenuron methyl BOC-L-Proline CHLOROPHOSPHONAZO III Methylparaben Kresoxim-methyl L-PROLINE-(4-3H(N)) Methyl salicylate D-Proline L-Hydroxyproline cis-4-Hydroxy-L-proline Methyl acrylate N-Boc-cis-4-Hydroxy-L-proline Thiophanate-methyl Methyl Methyl bromide N-Boc-trans-4-tosyloxy-L-proline methyl ester (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate N-Boc-trans-4-Hydroxy-L-proline methyl ester

(2S,4S)-N-Boc-cis-4-hydroxy-L-proline methyl ester

N-Boc-cis-4-hydroxy-L-proline methyl ester, >97.0%(GC)

(2S,4S)-N-Boc-4-hydroxyproline methyl ester

1-tert-butyl 2-methyl cis-4-hydroxypyrrolidine-1,2-dicarboxylate

cis-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate

N-T-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER

N-ALPHA-T-BUTOXYCARBONYL-CIS-4-HYDROXY-L-PROLINE METHYL ESTER

N-Boc-cis-4-hydroxy-L-proline Methyl ester, 97%, 97%

Boc-L-cis-4-Hydroxyproline methyl ester

1-tert-butyl 2-methyl (2S,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate

N-t-BOC-cis-4-HYDROXYL-L-PROLINE METHYL ESTER

cis-N-Boc-4-hydroxy-L-proline Methyl Ester

Methyl (4S)-N-Boc-4-hydroxy-L-prolinate

O1-tert-Butyl O2-methyl (2S,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate

Boc-cis-L-Hyp-OMe

cis-N-Boc-4-hydroxy-L-proline Methyl Ester,99%e.e.

N-ALPHA-T-BUTOXYCARBONYL-CIS-L-4-HYDROXYPROLINE METHYL ESTER

N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ESTER

N-BOC-CIS-4-HYDROXY-L-PROLINE METHYL ES&

METHYL CIS-1-BOC-4-HYDROXY-L-PROLINATE

Boc-cis-hydroxyproline methyl ester

(2S,4S)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate

BOC-CIS-HYDROXYPROLINE-OME

BOC-CIS-HYP-OME

BOC-CIS-L-4-HYDROXYPROLINE METHYL ESTER

Boc-cis-4-Hydroxy-L-proline methyl ester

Boc-cis-hyp-ome ,97%

1-tert-butyl 2-Methyl (2S)-4-hydroxypyrrolidine-1,2-dicarboxylate

N-Boc-cis-4-Hydro×y-L-proline Methyl ester

(2S,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester

N-Boc-cis-4-hydroxy-L-proline Methyl ester

N-Boc-cis-4-hydroxy-L-proline Methyl ester

cis-Boc-Hyp-OMe

N-(tert-Butoxycarbonyl)-cis-4-hydroxy-L-proline Methyl Ester

1,2-Pyrrolidinedicarboxylicacid, 4-hydroxy-, 1-(1,1-diMethylethyl) 2-Methyl ester, (2S,4S)-

N-Boc-cis-4-hydroxy-L-proline methyl, 97%

Boc-L-cis-Hyp-OMe

N-Boc-cis-Hyp-Ome

1-o-tert-butyl 2-o-methyl (2s,4s)-4-hydroxypyrrolidine-1,2-dicarboxylate

N-(tert-Butoxycarbonyl)-cis-4-hydroxy-L-prolineMethylEster&gt

N-Boc-cis-4-Hydroxy-L

(2S,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl 2-Methyl Ester

N-Boc-cis-4-Hydroxy-L-proline methyl ester USP/EP/BP

(2S,4S)-1-tert-Butoxycarbonyl-4-hydroxypyrrolidine-2-carboxylic acid methyl ester

2-Methyl 1-(2-methyl-2-propanyl) (2S,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate

(2S,4S)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate/N-Boc-cis-4-Hydroxy-L-proline methyl ester

N-Boc-cis-4-hydroxy-<sc>L</sc>-proline methyl ester

(2S,4S)-1-BOC-4-Hydroxy-pyrrolidine-2-carboxylic acid methyl ester

102195-79-9

Unnatural Amino Acid Derivatives

Specialty Synthesis

Peptide Synthesis

Proline Derivatives

Heterocycles

Peptide Synthesis

Proline Derivatives

Unnatural Amino Acid Derivatives