4-(Trifluoromethyl)benzylamine
- Product Name
- 4-(Trifluoromethyl)benzylamine
- CAS No.
- 3300-51-4
- Chemical Name
- 4-(Trifluoromethyl)benzylamine
- Synonyms
- PTF-BYM;p-CF3-benzylamine;4-(Trifluoromethy;RARECHEM AL BW 0030;4-triMethylbenzylaMine;4-AMINOMETHYLBENZOTRIFLUORIDE;-(Trifluoromethyl)benzylamine;P-(TRIFLUOROMETHYL)BENZYLAMINE;4-(TRIFLUOROMETHYL)BENZYLAMINE;4-(three fluoroMethyl)benzyl aMine
- CBNumber
- CB1251340
- Molecular Formula
- C8H8F3N
- Formula Weight
- 175.15
- MOL File
- 3300-51-4.mol
4-(Trifluoromethyl)benzylamine Property
- Melting point:
- 43 °C
- Boiling point:
- 79-82 °C (15 mmHg)
- Density
- 1.229 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.464(lit.)
- Flash point:
- 167 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 8.60±0.10(Predicted)
- form
- Liquid
- Specific Gravity
- 1.229
- color
- Clear colorless to light yellow
- Sensitive
- Air Sensitive
- BRN
- 2640698
- InChI
- InChI=1S/C8H8F3N/c9-8(10,11)7-3-1-6(5-12)2-4-7/h1-4H,5,12H2
- InChIKey
- PRDBLLIPPDOICK-UHFFFAOYSA-N
- SMILES
- C1(CN)=CC=C(C(F)(F)F)C=C1
- CAS DataBase Reference
- 3300-51-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,C
- Risk Statements
- 36/37/38-34
- Safety Statements
- 26-36-45-36/37/39
- RIDADR
- 2735
- WGK Germany
- 3
- Hazard Note
- Corrosive
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 263508
- Product name
- 4-(Trifluoromethyl)benzylamine
- Purity
- 97%
- Packaging
- 1g
- Price
- $39.7
- Updated
- 2025/07/31
- Product number
- 263508
- Product name
- 4-(Trifluoromethyl)benzylamine
- Purity
- 97%
- Packaging
- 10g
- Price
- $195.7
- Updated
- 2025/07/31
- Product number
- T1508
- Product name
- 4-(Trifluoromethyl)benzylamine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $45
- Updated
- 2025/07/31
- Product number
- T1508
- Product name
- 4-(Trifluoromethyl)benzylamine
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $177
- Updated
- 2025/07/31
- Product number
- T899035
- Product name
- 4-(Trifluoromethyl)benzylamine
- Packaging
- 5g
- Price
- $65
- Updated
- 2021/12/16
4-(Trifluoromethyl)benzylamine Chemical Properties,Usage,Production
Chemical Properties
clear colorless to light yellow liquid
Uses
4-(Trifluoromethyl)benzylamine has been used in the synthesis of 3-[(2,4-dioxothiazolidin-5-yl)methyl]benzamide derivatives.
Synthesis
16939-49-4
3300-51-4
General procedure for the synthesis of 4-(trifluoromethyl)benzylamine from the compound (CAS:16939-49-4): 5.00 g (26.4 mmol) of 4-trifluoromethylbenzaldehyde oxime was dissolved in methanol, followed by the addition of 4.0 g (109.7 mmol) of hydrogen chloride gas and 252 mg of the same catalyst as in Example 1, and the reaction was carried out with continuous stirring for 3 hours. The reaction was carried out at 10 atm hydrogen pressure and room temperature (about 25°C). Upon completion of the reaction, the catalyst was removed and ether was added to the reaction mixture and neutralized with aqueous sodium hydroxide. Analysis of the separated ether layer by gas chromatography confirmed the formation of 4-trifluoromethylbenzylamine in 93.6% yield.
References
[1] Patent: US6331649, 2001, B1
[2] Patent: WO2009/62949, 2009, A1. Location in patent: Page/Page column 10-11
4-(Trifluoromethyl)benzylamine Preparation Products And Raw materials
Raw materials
Preparation Products
4-(Trifluoromethyl)benzylamine Suppliers
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- Country
- France
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View Lastest Price from 4-(Trifluoromethyl)benzylamine manufacturers
- Product
- 4-(Trifluoromethyl)benzylamine 3300-51-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-12-09
- Product
- 4-(Trifluoromethyl)benzylamine 3300-51-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-07-11
- Product
- 4-(Trifluoromethyl)benzylamine 3300-51-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11