N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide

Product Name: N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide
CAS No.: 1139453-98-7
Chemical Name: N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide
Synonyms: Nintedanib-003;Intedanib Impurity 12;Intedanib Impurity 27;Nintedanib Intermediate 1;N,4-Dimethyl-N-(4-nitrophenyl)-1-piperazineacetamide;1-Piperazineacetamide, N,4-dimethyl-N-(4-nitrophenyl)-;N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acet...;N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide;N-Methyl-2-(4-methyl-1-piperazinyl)-N-(4-nitrophenyl)acetamide;N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetami...
CBNumber: CB12520770
Molecular Formula: C14H20N4O3
Formula Weight: 292.33
MOL File: 1139453-98-7.mol

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N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide Property

Melting point:: 94 - 96°C
Boiling point:: 446.9±40.0 °C(Predicted)
Density: 1.230
storage temp.: 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 7.43±0.10(Predicted)
form: Solid
color: Pale Yellow to Light Yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: M327435
Product name: N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide
Packaging: 500mg
Price: $460
Updated: 2021/12/16

Matrix Scientific

Product number: 143764
Product name: N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide
Purity: 95%
Packaging: 1g
Price: $778
Updated: 2021/12/16

Matrix Scientific

Product number: 143764
Product name: N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide
Purity: 95%
Packaging: 5g
Price: $1828
Updated: 2021/12/16

Crysdot

Product number: CD11347829
Product name: N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide
Purity: 95+%
Packaging: 100mg
Price: $70
Updated: 2021/12/16

Crysdot

Product number: CD11347829
Product name: N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide
Purity: 95+%
Packaging: 250mg
Price: $113
Updated: 2021/12/16

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N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide Chemical Properties,Usage,Production

Uses

N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide is used as a reactant in the synthetic preparation of 6-methoxycarbonyl-substituted indolinones, such as Intedanib (I666650), which is a triple angiokinase inhibitor and antitumor agent.

N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide Suppliers

China 99 India 5 United Kingdom 1 United States 6 Global 111

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
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Jinan Trio PharmaTech Co., Ltd.

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Fax: +86 (531) 55696010 QQ 1762738062
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Country: China
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SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD.

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Chengdu D-innovation Pharmaceutical Co.，LTD

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Syncozymes (Shanghai) Co.,Ltd.

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Jinan XuanDe Chemical Co., Ltd.

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ChemStrong Scientific Co.,Ltd

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Lihe Wuhan New Chemical Materials Co., Ltd.

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Shanghai KunRaise Chemical Technology Co., Ltd

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Shanghai Send Pharmaceutical Technology Co., Ltd.

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View Lastest Price from N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide manufacturers

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide 1139453-98-7
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2021-09-24

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: N,4-Dimethyl-N-(4-nitrophenyl)-1-piperazineacetamide 1139453-98-7
Price: US $3.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10kg
Release date: 2021-11-26

Career Henan Chemical Co

Product: N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide 1139453-98-7
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: 100kg
Release date: 2018-12-20

1139453-98-7, N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamideRelated Search:

2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide Methyl oxindole-5-carboxylate Nintedanib N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide Methyl 1-acetyl-2-oxoindoline-6-carboxylate N-(4-aMinophenyl)-2-chloro-N-MethylacetaMide 1-Chloro-4-(trimethoxymethyl)benzene 1-(2-chloroacetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester BIBF 1202 Nintedanib Ethanesulfonate Salt 1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide 2-broMo-N-Methyl-N-(4-nitrophenyl)acetaMide 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE BIBF-1120 (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Nidanib Impurity 12: N-methyl-2- (4-methylpiperazin-1-yl) -N- (4-nitrophenyl) -acetamide

N-Methyl-2-(4-methyl-1-piperazinyl)-N-(4-nitrophenyl)acetamide

N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide

N,4-Dimethyl-N-(4-nitrophenyl)-1-piperazineacetamide

Nintedanib impurity 2/N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide

Nintedanib Intermediate 1

Intedanib Impurity 12

Nintedanib-003

1-Piperazineacetamide, N,4-dimethyl-N-(4-nitrophenyl)-

N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acet...

N,4-Dimethyl-N-(4-Nitrophenyl)-1-Piperazineacetamide(Under Development)

N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetami...

Intedanib Impurity 27

1139453-98-7

Intermediate of BIBF-1120 and PKI587