VU 0364439
- Product Name
- VU 0364439
- CAS No.
- 1246086-78-1
- Chemical Name
- VU 0364439
- Synonyms
- CS-629;VU 0364439;VU 0364439 10MG;VU 0364439, >=98%;VU 0364439 USP/EP/BP;VU0364439/VU-0364439;VU 0364439;VU0364439; VU-0364439;N-(3-Chloro-4-(N-(2-chlorophenyl)sulfamoyl)phenyl)picolinamide;N-[3-Chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-2-pyridinecarboxamide;2-PyridinecarboxaMide, N-[3-chloro-4-[[(2-chlorophenyl)aMino]sulfonyl]phenyl]-
- CBNumber
- CB12596591
- Molecular Formula
- C18H13Cl2N3O3S
- Formula Weight
- 422.29
- MOL File
- 1246086-78-1.mol
VU 0364439 Property
- Density
- 1.538±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- ≥21.11 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
- form
- solid
- pka
- 7.71±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 16296
- Product name
- VU0364439
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 16296
- Product name
- VU0364439
- Packaging
- 5mg
- Price
- $109
- Updated
- 2024/03/01
- Product number
- 16296
- Product name
- VU0364439
- Packaging
- 10mg
- Price
- $169
- Updated
- 2024/03/01
- Product number
- 16296
- Product name
- VU0364439
- Packaging
- 50mg
- Price
- $533
- Updated
- 2024/03/01
- Product number
- 4371
- Product name
- VU0364439
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $707
- Updated
- 2021/12/16
VU 0364439 Chemical Properties,Usage,Production
Uses
VU 0364439 is a mGlu4 positive allosteric modulator (PAM) (1,2).
References
[1]. lucyna pomierny-chamioło, kinga rup, bartosz pomierny, et al. metabotropic glutamatergic receptors and their ligands in drug addiction. pharmacology & therapeutics, 2014, 142:281-305.
[2]. albert j. robichaud, darren w. engers, craig w. lindsley, et al. recent progress on the identification of metabotropic glutamate 4 receptor ligands and their potential utility as cns therapeutics. acs chemical neuroscience, 2011, 2:433-449.
[3]. colleen m. niswender, kari a. johnson, c. david weaver, et al. discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4. mol. pharmacol., 2008, 74(5):1345-1358.
[4]. darren w. engers, patrick r. gentry, richard williams, et al. synthesis and sar of novel, 4-(phenylsulfamoyl)phenylacetamide mglu4 positive allosteric modulators (pams) identified by functional high-throughput screening (hts). bioorg. med. chem. lett., 2010, 20:5175-5178.
VU 0364439 Preparation Products And Raw materials
Raw materials
Preparation Products
VU 0364439 Suppliers
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