GSK2838232

Product Name: GSK2838232
CAS No.: 1443461-21-9
Chemical Name: GSK2838232
Synonyms: CS-947;EX-A202;GSK2838232;HIV Inhibitor GS2838232;GSK2838232(GSK2838232A);HIV Inhibitor GSK2838232;GSK-2838232A; GSK 2838232A;(3beta)-3-(3-Carboxy-3-methyl-1-oxobutoxy)-17-[(1R)-2-[[(3-chlorophenyl)methyl][2-(dimethylamino)ethyl]amino]-1-hydroxyethyl]-28-norlup-18-en-21-one;28-Norlup-18-en-21-one, 3-(3-carboxy-3-methyl-1-oxobutoxy)-17-[(1R)-2-[[(3-chlorophenyl)methyl][2-(dimethylamino)ethyl]amino]-1-hydroxyethyl]-, (3β)-
CBNumber: CB12664173
Molecular Formula: C48H73ClN2O6
Formula Weight: 809.56
MOL File: 1443461-21-9.mol

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GSK2838232 Property

Boiling point:: 817.1±65.0 °C(Predicted)
Density: 1.17±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Powder
pka: 4.48±0.28(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology

Product number: B5818
Product name: GSK2838232
Packaging: 5mg
Price: $551
Updated: 2021/12/16

ApexBio Technology

Product number: B5818
Product name: GSK2838232
Packaging: 10mg
Price: $788
Updated: 2021/12/16

ApexBio Technology

Product number: B5818
Product name: GSK2838232
Packaging: 50mg
Price: $2363
Updated: 2021/12/16

ApexBio Technology

Product number: B5818
Product name: GSK2838232
Packaging: 100mg
Price: $3308
Updated: 2021/12/16

DC Chemicals

Product number: DC7847
Product name: HIVInhibitorGSK2838232
Purity: >98%
Packaging: 1g
Price: $2500
Updated: 2021/12/16

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GSK2838232 Chemical Properties,Usage,Production

Biological Activity

gsk2838232 is an hiv-1 maturation inhibitor [1] [2].hiv-1 maturation inhibitors disrupt the cleavage of the hiv-1 gag protein immediate precursor by the enzyme hiv-1 protease. maturation inhibitors bind the gag protein, which leads to the formation of immature, noninfectious virus particles incapable of infecting other cells. also, maturation inhibitors inhibit hiv infections with resistance.gsk2838232 is a hiv-1 maturation inhibitor and is active against a broad range of isolates, including those resistant to bevirimat [1]. gsk2838232 was developed for the treatment of chronic hiv infection. a phase i study in hiv-negative individuals had been completed. single doses of 5, 10 or 20 mg gsk2838232 were used to evaluate the initial safety, tolerability, pharmacokinetics profile, and the effects of food and ritonavir on gsk2838232’s bioavailability and pharmacokinetics [2].

References

[1]. olender sa, taylor bs, wong m, et al. croi 2015: advances in antiretroviral therapy. croi 2015 highlights: antiretroviral therapy volume 23 issue 1 march/april 2015.
[2]. horn t, collins s. the antiretroviral pipeline. antiretrovirals, 2014 pipeline report.

GSK2838232 Preparation Products And Raw materials

Raw materials

Preparation Products

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GSK2838232 Suppliers

China 44 India 1 United States 4 Global 49

Shanghai Boyle Chemical Co., Ltd.

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HangZhou YuHao Chemical Technology Co., Ltd.

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AdooQ Bioscience CHINA

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Shanghai Lollane Biological Technology Co.,Ltd.

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SPIRO PHARMA

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ShangHai Biochempartner Co.,Ltd

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Amadis Chemical Company Limited

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Medi-tech Bioscientific Co., Ltd.

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Chuzhou KeMail Chemical Technology Co., Ltd

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Shanghai BetterBioChem Co., Ltd.

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Email: sales@betterbiochem.com
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View Lastest Price from GSK2838232 manufacturers

Career Henan Chemical Co

Product: (3beta)-3-(3-Carboxy-3-methyl-1-oxobutoxy)-17-[(1R)-2-[[(3-chlorophenyl)methyl][2-(dimethylamino)ethyl]amino]-1-hydroxyethyl]-28-norlup-18-en-21-one 1443461-21-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2019-12-23

Career Henan Chemical Co

Product: (3beta)-3-(3-Carboxy-3-methyl-1-oxobutoxy)-17-[(1R)-2-[[(3-chlorophenyl)methyl][2-(dimethylamino)ethyl]amino]-1-hydroxyethyl]-28-norlup-18-en-21-one 1443461-21-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2019-12-20

1443461-21-9, GSK2838232Related Search:

GSK2814338 GSK-2256098 GSK-25 S)-1-(sec-butyl)-N-((4,6-diMethyl-2-oxo-1,2-dihydropyridin-3-yl)Methyl)-3-Methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxaMide 7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMine GSK 2801 GSK2636771 GSK2879552 GSK2795039 GSK 2330672

GSK2838232

(3beta)-3-(3-Carboxy-3-methyl-1-oxobutoxy)-17-[(1R)-2-[[(3-chlorophenyl)methyl][2-(dimethylamino)ethyl]amino]-1-hydroxyethyl]-28-norlup-18-en-21-one

GSK-2838232A; GSK 2838232A

CS-947

GSK2838232(GSK2838232A)

HIV Inhibitor GS2838232

28-Norlup-18-en-21-one, 3-(3-carboxy-3-methyl-1-oxobutoxy)-17-[(1R)-2-[[(3-chlorophenyl)methyl][2-(dimethylamino)ethyl]amino]-1-hydroxyethyl]-, (3β)-

EX-A202

HIV Inhibitor GSK2838232

1443461-21-9

C48H73ClN2O6