ChemicalBook > CAS DataBase List > tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate

tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate

Product Name
tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate
CAS No.
1210348-34-7
Chemical Name
tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate
Synonyms
Tert-Butyl(1R,2S,5S)-2-azido-5-[(diMethylaMino)carbonyl]cyclohexylcarbaMate oxalic acid;N-[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]-Carbamic acid, 1,1-dimethylethyl ester, ethanedioate (1:1);Edoxaban-1;EBD3313800;Yidu Saban Impurity A;Edoxaban Intermediate II;Idosaiban intermediate 2;2EthanediaMide iMpurity A;EthanediaMide iMpurity A;(1S,2R,4S)-2-[(tert-Butoxyc
CBNumber
CB12670860
Molecular Formula
C16H29N3O7
Formula Weight
375.42
MOL File
1210348-34-7.mol
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tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate Property

storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White
InChI
InChI=1/C14H27N3O3.C2H2O4/c1-14(2,3)20-13(19)16-11-8-9(6-7-10(11)15)12(18)17(4)5;3-1(4)2(5)6/h9-11H,6-8,15H2,1-5H3,(H,16,19);(H,3,4)(H,5,6)/t9-,10-,11+;/s3
InChIKey
IERZZGXDUZIMSC-FPTARDKGNA-N
SMILES
C(=O)(O)C(=O)O.N([C@H]1[C@H](CC[C@H](C(=O)N(C)C)C1)N)C(=O)OC(C)(C)C |&1:7,8,11,r|
CAS DataBase Reference
1210348-34-7
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B809515
Product name
tert-Butyl[(1R,2S,5S)-2-Amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamateOxalate
Packaging
1g
Price
$65
Updated
2021/12/16
ChemScene
Product number
CS-M3400
Product name
tert-Butyl[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamateoxalate
Packaging
5g
Price
$78
Updated
2021/12/16
ChemScene
Product number
CS-M3400
Product name
tert-Butyl[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamateoxalate
Packaging
10g
Price
$132
Updated
2021/12/16
AK Scientific
Product number
9769AF
Product name
tert-Butyl[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamateoxalate
Packaging
5g
Price
$238
Updated
2021/12/16
ChemScene
Product number
CS-M3400
Product name
tert-Butyl[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamateoxalate
Packaging
25g
Price
$263
Updated
2021/12/16
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tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate Chemical Properties,Usage,Production

Uses

tert-Butyl [(1R,2S,5S)-2-Amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate Oxalate is a starting material and useful building block of various pharmaceuticals.

Uses

Tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate is also called EthanediaMide iMpurity A. It is a starting material and useful component of various pharmaceuticals. As an organic synthesis intermediate and pharmaceutical intermediate. It could be used in the synthesis and research of the EthanediaMide.

Synthesis

Tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate is prepared by the reaction of benzyl N-[(1S,2R,4S)-2-{[(tert-butoxy)carbonyl]amino}-4-(dimethylcarbamoyl)cyclohexyl]carbamate and Oxalic Acid. The steps are as follows:
Pd-C (230 mg) was added to a solution (35 mL) of benzyl t-butyl{(1S,2R,4S)-4-[(dimethylamino)carbonyl]cyclohexan-1,2-diyl}biscarbamate (2.3 g) in ethanol, and the mixture was stirred in a hydrogen atmosphere for 16 hours. Pd-C was removed by filtration, and the filtrate was concentrated under reduced pressure. Ethyl acetate (20 mL) and anhydrous oxalic acid (493.6 mg) were added to the residue, followed by stirring at room temperature for 17 hours. The formed crystals were recovered by filtration, to thereby yield 1.93 g of the Tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate.

tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate Suppliers

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View Lastest Price from tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate manufacturers

Anhuyan (Hainan) Biotechnology Co., LTD
Product
tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate 1210348-34-7
Price
US $0.00-0.00/KG
Min. Order
0.0001KG
Purity
99.99%
Supply Ability
20000T
Release date
2025-06-16
Wuhan Biocar Pharmacy CO.,Ltd.
Product
tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate 1210348-34-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
0.99
Supply Ability
800KG
Release date
2025-03-11
Shanghai Joiny Pharmaceutical Co.,LTD
Product
tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl] cyclohexyl]carbamate oxalate 1210348-34-7
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2024-01-12

1210348-34-7, tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalateRelated Search:

2-BroMo-5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine (1R,3R,4R)-3-AMino-4-hydroxy-cyclohexanecarboxylic acid ethyl ester 2-Amino-5-chloropyridine EthanediaMide, N1-(5-chlo... EthanediaMide, N1-(5-chlo... (1R,2R,4S)-2-[(tert-butoxycarbonyl)aMino]-4-[(diMethylaMino)carbonyl]cyclohexyl Methanesulfonate Thiazolo[5,4-c]pyridine, 4,5,6,7-tetrahydro-5-methyl- 2-(((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)amino)-2-oxoacetic acid EthanediaMide iMpurity F EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4R)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride Tert-Butyl(1R,2S,5S)-2-azido-5-[(dimethylamino)carbonyl]cyclohexylcarbamate oxalic acid Ethyl 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate hydrochloride tert-butyl (1R,2S,5S)-2-aMino-5-(diMethylcarbaMoyl)cyclohexylcarbaMate Argatroban Flurbiprofen VILAZODONE (1R,3S,4R)-3-Amino-4-hydroxy-cyclohexanecarboxylic acid ethyl ester hydrochloride

  • Tert-Butyl(1R,2S,5S)-2-azido-5-[(diMethylaMino)carbonyl]cyclohexylcarbaMate oxalic acid
  • oxalic acid tert-butyl N-[(1R,2S,5S)-2-aMino-5-(diMethylcarbaMoyl)cyclohexyl]carbaMate
  • (2-Azido-5-diMethylcarbaMoyl-cyclohexyl)-carbaMic acid tert-butyl esteroxalic acid
  • EthanediaMide iMpurity A/Edoxaban Intermediate II
  • tert-butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate oxalic acid
  • Edoxaban-1
  • N-[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]-Carbamic acid, 1,1-dimethylethyl ester, ethanedioate (1:1)
  • 2EthanediaMide iMpurity A
  • tert-Butyl [(1R,2S,5S)-2-aMino-5-[(diMethylaMino)carbonyl]cyclohexyl]carbaMate oxalate
  • tert-Butyl [(1R,2S,5S)-2-aMino-5-[(diMethylaMino)carbonyl]cyclohexyl]carbaMate oxalate(for Edoxaban)
  • tert-butyl N-[(1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl]carbamate
  • (1S,2R,4S)-2-[(tert-Butoxycarbonyl)Amino ]-4-[( dimethylamino)carbonyl]- cyclohexyl ammonia oxalate
  • tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate oxalate
  • Edoxaban Intermediate II
  • tert-butyl N-[(1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl]carbamate oxalate
  • Edoxaban Impurity 15 Oxalate
  • Tert-Butyl(1R,2S,5S)-2-azido-5-[(diMethylaMino)carbonyl]cyclohexylcarbaMate oxalate
  • (1S,2R,4S)-2-[(tert-Butoxyc
  • tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate(For export only)
  • Tert-butyl(1R, 2S, 5S)-2-amino-5-((dimethylamino)carbonyl)cyclohexylcarbamate oxalic acid
  • (1S,2R,4S)-2-[(tert-Butoxycarbonyl]- cyclohexyl ammonia oxalate
  • (1s, 2R, 4S) - 1-amino-4 - (dimethylaminocarbonyl) - cyclohexyl-2-carbamate tert butyl oxalic acid
  • Idosaiban intermediate 2
  • ert-Butyl[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamateoxalate
  • EBD3313800
  • Tertiary Butyl [1R,2S, 5S]-2-Amino-5-Dimethylcarboyl) Cyclohexylcarbamate Oxalate
  • tert-butyl (1R,2S,5S)-5-(dimethylcarbamoyl)-2-aminocyclohexylcarbamate oxalate
  • Yidu Saban Impurity A
  • Edoxaban Impurity A（Oxalate）
  • [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate
  • tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate carbamic acid
  • Tert-Butyl((1R,2S,5S)-2-amino-5-(dimethyl- carbamoyl)cyclohexyl)carbarmate oxalate
  • EthanediaMide iMpurity A
  • Edoxaban Impurity 9 Oxalate
  • N-[(1R,2S,5S)-2-azido-5-(dimethylcarbamoyl)cyclohexyl]-N-tert-butylcarbamate
  • (1S,2R,4S)-1-Amino-4-(dimethylaminocarbonyl)-cyclohexyl-2-carbamicacidtert-butylesteroxalate
  • teri-Butyl [(1R,2S,5S)-2-amino-5-(dimethvlcarbamovl'cvclohexvllcarbamate oxalate
  • tert-Butyl[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyllcyclohexyllcarbamate oxalate
  • tert-Butyl [(1R,2S,5S)-2-amino -5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate (Intermediate of Edoxaban mesylate)
  • 2-(4-Cyanophenylamino)acetic acid (Intermediate of Dabigatran etexilate mesylate)
  • 1210348-34-7
  • 365998-36-8
  • C14H27N3O3C2H2O4