CK-636

Description In vitro

Product Name: CK-636
CAS No.: 442632-72-6
Chemical Name: CK-636
Synonyms: CK-636;CS-1421;CK-0944636;CK-636, >=98%;CK-636 USP/EP/BP;CK-636(CK-0944636;CK-636;CK636; CK 636;CK-636,CK-0944636, >98%;CK636; CK 636; CK-0944636; CK0944636; CK 0944636;N-[2-(2-Methyl-1H-indol-3-yl)ethyl]-2-thiophenecarboxamide
CBNumber: CB12685323
Molecular Formula: C16H16N2OS
Formula Weight: 284.38
MOL File: 442632-72-6.mol

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CK-636 Property

storage temp.: Keep in dark place,Sealed in dry,2-8°C
solubility: DMSO: ≥20mg/mL
form: powder
color: peach to light tan
InChIKey: ACAKNPKRLPMONU-UHFFFAOYSA-N
CAS DataBase Reference: 442632-72-6

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C7374
Product name: CK-636
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $106
Updated: 2024/03/01

Sigma-Aldrich

Product number: C7374
Product name: CK-636
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $397
Updated: 2023/01/07

Cayman Chemical

Product number: 16243
Product name: CK-636
Purity: ≥98%
Packaging: 5mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 16243
Product name: CK-636
Purity: ≥98%
Packaging: 10mg
Price: $115
Updated: 2024/03/01

Cayman Chemical

Product number: 16243
Product name: CK-636
Purity: ≥98%
Packaging: 25mg
Price: $270
Updated: 2024/03/01

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CK-636 Chemical Properties,Usage,Production

Description

CK-636 is an Arp2/3 complex inhibitor with IC50 of 4 μM, 24 μM and 32 μM for inhibition of actin polymerization induced by human, fission yeast and bovine Arp2/3 complex, respectively.

In vitro

CK-636 inhibits actin polymerization mediated by Arp2/3 complex in live cells, and reduces the formation of actin filament comet tails by Listeria in infected SKOV3 cells. CK-636 inhibits lamellipodia formation at the leading edges of migrating T cells, and causes reduced velocity. In addition, a substantial fraction of CK-636-treated T cells on zigzag patterns with an acute turning angle are trapped near the interfaces formed by the turning points of zigzag patterns.

Uses

CK-636 is a small molecule that inhibits Actin-related protein 2/3 (Arp2/3) (1). Arp2/3 is a 7 subunits protein complex that regulates actin cytoskeleton (2). CK-636 interacts with Arp2/3 and prevents actin polymerization.

CK-636 Preparation Products And Raw materials

Raw materials

Preparation Products

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CK-636 Suppliers

China 81 India 2 United States 15 Global 98

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7815
Advantage: 57

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4654
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66099280 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19918
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4863
Advantage: 58

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2784
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AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2989
Advantage: 60

Shanghai JiYi Biotechnology Co. Ltd.

Tel: 13621943973
Fax: -
Email: sales@shjiyipharmatech.com
Country: China
ProdList: 1166
Advantage: 55

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4153
Advantage: 55

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View Lastest Price from CK-636 manufacturers

Career Henan Chemical Co

Product: CK-636 442632-72-6
Price: US $5.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2019-09-03

442632-72-6, CK-636Related Search:

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CK-636

N-(2-(2-METHYL-1H-INDOL-3-YL)ETHYL)THIOPHENE-2-CARBOXAMIDE

N-[2-(2-Methyl-1H-indol-3-yl)ethyl]-2-thiophenecarboxamide

CK-636, >=98%

CK-0944636

CK-636 N-[2-(2-Methyl-1H-indol-3-yl)ethyl]-2-thiophenecarboxamide

N-[2-(2-Methyl-1H-indol-3-yl)ethyl]-2-thiophenecarboxamide CK636

CK-636;CK636; CK 636

CK-636(CK-0944636

CS-1421

CK636; CK 636; CK-0944636; CK0944636; CK 0944636

CK-636,CK-0944636, >98%

2-Thiophenecarboxamide, N-[2-(2-methyl-1H-indol-3-yl)ethyl]-

CK-636 USP/EP/BP

CK 0944636,CK-636,Inhibitor,Actin-related protein 2/3 complex,CK0944636,CK636,Arp2/3 Complex,inhibit

442632-72-6

Inhibitors