ChemicalBook > CAS DataBase List > 1(2H)-Phthalazinone

1(2H)-Phthalazinone

Product Name
1(2H)-Phthalazinone
CAS No.
119-39-1
Chemical Name
1(2H)-Phthalazinone
Synonyms
phthalazinone;Phthalazin-1(2H)-one;PHTHALAZONE;1-Phthalazinone;PTLZ;Pthalazone;1-phthalazinol;Phthalazone>1,2H-PHTHALAZONE;phthalazin-1-one
CBNumber
CB1282098
Molecular Formula
C8H6N2O
Formula Weight
146.15
MOL File
119-39-1.mol
More
Less

1(2H)-Phthalazinone Property

Melting point:
183-185 °C(lit.)
Boiling point:
337°C(lit.)
Density 
1.2312 (rough estimate)
refractive index 
1.4900 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Crystalline Powder
pka
12.29±0.20(Predicted)
color 
Off-white to pale yellow
BRN 
3654
InChIKey
IJAPPYDYQCXOEF-UHFFFAOYSA-N
CAS DataBase Reference
119-39-1(CAS DataBase Reference)
EPA Substance Registry System
1(2H)-Phthalazinone (119-39-1)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-68-36/37/38
Safety Statements 
22-24/25-36/37/39-26
WGK Germany 
3
RTECS 
TH9185000
HazardClass 
IRRITANT
HS Code 
29339990
Hazardous Substances Data
119-39-1(Hazardous Substances Data)
Toxicity
mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00139,
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P39001
Product name
Phthalazone
Purity
99%
Packaging
5g
Price
$53.1
Updated
2024/03/01
Sigma-Aldrich
Product number
P39001
Product name
Phthalazone
Purity
99%
Packaging
100g
Price
$362
Updated
2023/06/20
TCI Chemical
Product number
P1179
Product name
Phthalazone
Purity
>98.0%(GC)
Packaging
25g
Price
$36
Updated
2024/03/01
TCI Chemical
Product number
P1179
Product name
Phthalazone
Purity
>98.0%(GC)
Packaging
500g
Price
$255
Updated
2024/03/01
TRC
Product number
P382600
Product name
Phthalazone
Packaging
1g
Price
$65
Updated
2021/12/16
More
Less

1(2H)-Phthalazinone Chemical Properties,Usage,Production

Chemical Properties

Off-white to pale yellow crystalline powder

Uses

Phthalazone is a remarkable scaffold in drug discovery. Also, functions as an oxidative metabolic pathway of lenvatinib mediated by aldehyde oxidase.

Definition

ChEBI: Phthalazin-1(2H)-one is a member of phthalazines.

General Description

Pale yellow crystals. Insoluble in water.

Air & Water Reactions

Insoluble in water.

Fire Hazard

Flash point data for 1(2H)-Phthalazinone are not available. 1(2H)-Phthalazinone is probably combustible.

Purification Methods

Phthalazone crystallises from H2O or EtOH and sublimes in vacuo. [Beilstein 24 H 142, 24 24 III/IV 400.]

1(2H)-Phthalazinone Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1(2H)-Phthalazinone Suppliers

NingBo Sialon Chem Co., Ltd.
Tel
0574-28809768 18658497215
Fax
+86-574-56708448 / 28809708
Email
sales@newsialon.com
Country
China
ProdList
40
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9413
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
More
Less

View Lastest Price from 1(2H)-Phthalazinone manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
1(2H)-Phthalazinone 119-39-1
Price
US $50.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10000
Release date
2023-10-30
airuikechemical co., ltd.
Product
1(2H)-Phthalazinone 119-39-1
Price
US $0.00-0.00/g
Min. Order
1g
Purity
99.99%
Supply Ability
20 tons
Release date
2024-04-09
Weijer International Trade (Hebei) Co., Ltd
Product
phthalazin-1(2H)-one 119-39-1
Price
US $150.00/KG
Min. Order
1KG
Purity
>99%
Supply Ability
50000kg/Month
Release date
2023-03-13

119-39-1, 1(2H)-PhthalazinoneRelated Search:


  • BENZO[D]PYRIDAZIN-1(2H)ONE
  • 2H-Phthalazin-1-one
  • 1(2H)-Phthalazinone, 98+%
  • 1,2-Dihydrophthalazine-1-one
  • Pthalazone
  • 1,2-Dihydro-1-oxophthalazine, Benzo[d]pyridazin-1(2H)-one, Phthalazone
  • 1(2H)-Phthalazinone, 98+% 5GR
  • Benzo[d]pyridazin-1(2H)one 1(2H)-Phthalazinone
  • Hydralazine IMpurity 01
  • Hydralazine Hydroxy IMpurity
  • phthalazin-1(4H)-one
  • 1-Phthalazinone
  • DIHYDROOXOPHTHALAZINE
  • 1,3-DIHYDRO-4-KETO-2 3-BENZODIAZINE
  • 1(2H)-PHTHALAZINONE
  • 1,2H-PHTHALAZONE
  • 1,2-DIHYDROPHTHALAZIN-1-ONE
  • phthalazin-1-one
  • phthalazinone
  • Phthalazin-1(2H)-one
  • 2,3-Phthalazinone
  • PTLZ
  • PHTHALAZONE
  • 1-phthalazinol
  • Phthalazone&gt
  • Phthalazin-1(2H)-one (Azelastine Impurity)
  • 119-39-1
  • 119-39-5
  • Heterocyclic Building Blocks
  • Pyridazines
  • Building Blocks
  • Aldehyde
  • Miscellaneous