ChemicalBook > CAS DataBase List > 1,5-DIAMINO-3-OXAPENTANE

1,5-DIAMINO-3-OXAPENTANE

Product Name
1,5-DIAMINO-3-OXAPENTANE
CAS No.
2752-17-2
Chemical Name
1,5-DIAMINO-3-OXAPENTANE
Synonyms
2,2'-Oxydiethanamine;2-(2-aminoethoxy)ethanamine;EDR 104;Oxyamine Ether;Amino-PEG1-Amine;2,2'-Oxybis(ethyL;Jeffamine EDR 104;2,2'-OXYDIETHYLAMINE;2,2’-oxybis-ethanamin;Di(2-aminoethyl) ether
CBNumber
CB1285190
Molecular Formula
C4H12N2O
Formula Weight
104.15
MOL File
2752-17-2.mol
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1,5-DIAMINO-3-OXAPENTANE Property

Boiling point:
69-71 °C (15 mmHg)
Density 
0,98 g/cm3
vapor pressure 
2.39hPa at 20℃
refractive index 
1.455-1.458
storage temp. 
2-8°C(protect from light)
form 
Liquid
pka
pK1: 8.62(+2);pK2: 9.59(+1) (30°C)
color 
Clear colorless
Water Solubility 
100g/L at 20℃
InChI
InChI=1S/C4H12N2O/c5-1-3-7-4-2-6/h1-6H2
InChIKey
GXVUZYLYWKWJIM-UHFFFAOYSA-N
SMILES
O(CCN)CCN
LogP
-2.12 at 22℃
CAS DataBase Reference
2752-17-2
EPA Substance Registry System
Ethanamine, 2,2'-oxybis- (2752-17-2)
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Safety

Hazard Codes 
C
Risk Statements 
34-41
Safety Statements 
45-36/37/39-26-39
RIDADR 
UN 2735 8/PG III
HazardClass 
8
PackingGroup 
III
HS Code 
29221990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TCI Chemical
Product number
O0278
Product name
2,2'-Oxybis(ethylamine)
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$261
Updated
2025/07/31
TCI Chemical
Product number
O0278
Product name
2,2'-Oxybis(ethylamine)
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$745
Updated
2025/07/31
TCI Chemical
Product number
O0278
Product name
2,2'-Oxybis(ethylamine)
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$2037
Updated
2025/07/31
TRC
Product number
E588923
Product name
2,2''-Oxydiethanamine
Packaging
100mg
Price
$75
Updated
2021/12/16
BroadPharm
Product number
BP-23107
Product name
Amino-PEG1-amine
Purity
98%
Packaging
1g
Price
$65
Updated
2021/12/16
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1,5-DIAMINO-3-OXAPENTANE Chemical Properties,Usage,Production

Description

Amino-PEG1-Amine is a water soluble PEG linker containing two amino groups. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

Chemical Properties

clear colorless liquid

Uses

2,2''-Oxydiethanamine is a coating resin modifier.

Definition

ChEBI: Diamino-poly(ethylene glycol) is a poly(ethylene glycol) terminated with -NH2 groups. It is a poly(ethylene glycol) derivative and a primary amino compound.

Flammability and Explosibility

Not classified

Synthesis

43113-25-3

2752-17-2

General procedure for the synthesis of 2,2'-oxydiethylamine from 2,2'-(oxybis(ethane-2,1-diyl))bis(isoindoline-1,3-dione): the raw material (575 mg, 0.83 mmol) was mixed with 80% hydrazine hydrate (8.3 mmol) in chloroform (10 mL) with reflux stirring for 4 hours. After completion of the reaction, the reaction mixture was treated with water and extracted with chloroform. The organic layer was dried with magnesium sulfate followed by evaporation of the solvent. Purification by distillation afforded the target product 2,2'-oxy diethylamine (9a) in 93% yield; boiling point 75-79°C/5 mmHg (literature value 31: 55-60°C/2 mmHg). The structure of the product was confirmed by 1H NMR (500 MHz, DMSO-d6) δ 8.31 (4H, br s), 3.32 (4H, t, J = 5.5 Hz), 2.63 (4H, t, J = 5.5 Hz); 13C NMR (500 MHz, DMSO-d6) δ 72.7, 41.3; and mass spectrum (FAB) m/z: 105 [ M + H] for confirmation.

References

[1] Tetrahedron, 2016, vol. 72, # 29, p. 4258 - 4272
[2] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1982, vol. 18, # 2, p. 193 - 196
[3] Khimiya Geterotsiklicheskikh Soedinenii, 1982, # 2, p. 246 - 249
[4] Journal of Organic Chemistry USSR (English Translation), 1980, vol. 16, p. 1124 - 1129
[5] Zhurnal Organicheskoi Khimii, 1980, vol. 16, # 6, p. 1301 - 1307

1,5-DIAMINO-3-OXAPENTANE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,5-DIAMINO-3-OXAPENTANE Suppliers

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2752-17-2, 1,5-DIAMINO-3-OXAPENTANERelated Search:

GLYCYL-DL-THREONINE Actinomycin D ALPHA-ERGOCRYPTINE BEAUVERICIN Neomycin sulfate VALINOMYCIN RIBOSTAMYCIN SULFATE SALT (1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL KRYPTOFIX(R) 221 1,4,10-TRIOXA-7,13-DIAZACYCLOPENTADECANE DIHYDROERGOTAMINE TARTRATE 2,2'-OXYBIS(ETHYLAMINE) DIHYDROCHLORIDE Sisomicin DL-2-AMINOPROPIONIC ANHYDRIDE 1,8-Diamino-3,6-dioxaoctane KRYPTOFIX(R) 211 CALCIUM IONOPHORE II BUTIROSIN DISULFATE

  • 2,2’-oxybis-ethanamin
  • 2,2'-OXYDIETHYLAMINE
  • 2,2'-DIAMINODIETHYL ETHER
  • 10-chloro-5H-phenanthridin-6-one
  • 2,2'-Oxybis(ethyL
  • 1,5-DIAMINO-3-OXAPENTANE
  • BIS(2-AMINOETHYL) ETHER
  • 1,5-DIAMINO-3-OXAPENTANE 98%
  • 2,2'-Oxybis(ethanamine)
  • 2,2'-Oxydiethanamine
  • 3-Oxapentane-1,5-diamine
  • Di(2-aminoethyl) ether
  • 2,2'-Oxybis(ethylamine),98%
  • Bis(2-aminoethyl) Ether 2,2'-Diaminodiethyl Ether 2,2'-Oxydiethylamine
  • 2-(2-Aminoethoxy)ethylamine
  • Amino-PEG1-Amine
  • 2-(2-aminoethoxy)ethanamine
  • 2-(2-aminoethoxy)ethan-1-amine
  • EDR 104
  • Jeffamine EDR 104
  • 3-Oxa-1,5-pentanediamine
  • Ethanamine, 2,2'-oxybis-
  • 2,2'-Oxybis(ethylamine)&gt
  • ,2'-Oxybis(ethylamine)
  • Oxyamine Ether
  • 2,2'-oxybis(ethan-1-amine)
  • 2,2'-Oxybis(ethylamine)
  • 2,2'-oxydi(ethylamine)
  • 2,2'-Oxydiethanamine , 2,2-Oxybis(ethylamine)
  • 2,2′-Oxybis(ethylamine), CAS 2752-17-2
  • 2,2'-Oxybis(ethylamine)
  • 2752-17-2
  • 1