(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid

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(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid

Product Name: (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid
CAS No.: 1639970-62-9
Chemical Name: (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid
Synonyms: LCZ703;LCZ696-14;LCZ-696 Impurity 16;LCZ696 impurities116;Sacubitril Impurity 32;LCZ696 impurities518-12;Sabatrol calcium impurity O;LCZ696(valsartan + sacubitril) impurity 14;(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoic acid;1-Pyrrolidinebutanoic acid, γ-([1,1'-biphenyl]-4-ylmethyl)-α-methyl-2,5-dioxo-, (αR,γS)-
CBNumber: CB12995772
Molecular Formula: C22H23NO4
Formula Weight: 365.42
MOL File: 1639970-62-9.mol

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(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid Property

Boiling point:: 624.1±55.0 °C(Predicted)
Density: 1.237±0.06 g/cm3(Predicted)
pka: 4.52±0.23(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: B592276
Product name: (2R,4S)-5-([1,1''-biphenyl]-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoicacid
Packaging: 100mg
Price: $1320
Updated: 2021/12/16

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(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid Chemical Properties,Usage,Production

Uses

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoic acid is an impurity compound of Valsartan (V095750). Valsartan is a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.

(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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1639970-62-9, (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acidRelated Search:

(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-4-(4-ethoxy-4-oxobutanamido)-2-methylbutanoic acid (R,E)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate sacubitril (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoate AHU-377 AHU-377 (heMicalciuM salt) (2R,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid LCZ696 interMediate Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate LCZ696 InteMediate (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid (2S,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid LCZ696 LCZ Impurity Sacubitril Impurity 72 (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoic acid hydrochloride 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- (S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one

(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid

LCZ703

LCZ-696 Impurity 16

Sacubitril Impurity 32

LCZ696-14

LCZ696(valsartan + sacubitril) impurity 14

1-Pyrrolidinebutanoic acid, γ-([1,1'-biphenyl]-4-ylmethyl)-α-methyl-2,5-dioxo-, (αR,γS)-

LCZ696 impurities116

LCZ696 impurities518-12

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoic acid

(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid

Sabatrol calcium impurity O

1639970-62-9

LCZ696