ChemicalBook > CAS DataBase List > (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid

(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid

Product Name
(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid
CAS No.
1639970-62-9
Chemical Name
(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid
Synonyms
LCZ703;LCZ696-14;LCZ-696 Impurity 16;LCZ696 impurities116;Sacubitril Impurity 32;LCZ696 impurities518-12;Sabatrol calcium impurity O;LCZ696(valsartan + sacubitril) impurity 14;1-Pyrrolidinebutanoic acid, γ-([1,1'-biphenyl]-4-ylmethyl)-α-methyl-2,5-dioxo-, (αR,γS)-;(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid
CBNumber
CB12995772
Molecular Formula
C22H23NO4
Formula Weight
365.42
MOL File
1639970-62-9.mol
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(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid Property

Boiling point:
624.1±55.0 °C(Predicted)
Density 
1.237±0.06 g/cm3(Predicted)
pka
4.52±0.23(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B592276
Product name
(2R,4S)-5-([1,1''-biphenyl]-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoicacid
Packaging
100mg
Price
$1320
Updated
2021/12/16
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(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid Chemical Properties,Usage,Production

Uses

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoic acid is an impurity compound of Valsartan (V095750). Valsartan is a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.

(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid Suppliers

China 35 India 2 United States 2 Global 39

1639970-62-9, (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acidRelated Search:

(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-4-(4-ethoxy-4-oxobutanamido)-2-methylbutanoic acid (R,E)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate sacubitril (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoate AHU-377 AHU-377 (heMicalciuM salt) (2R,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid LCZ696 interMediate Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate LCZ696 InteMediate (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid (2S,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid LCZ696 LCZ Impurity Sacubitril Impurity 72 (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoic acid hydrochloride 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- (S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one

  • (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid
  • LCZ703
  • LCZ-696 Impurity 16
  • Sacubitril Impurity 32
  • LCZ696-14
  • LCZ696(valsartan + sacubitril) impurity 14
  • 1-Pyrrolidinebutanoic acid, γ-([1,1'-biphenyl]-4-ylmethyl)-α-methyl-2,5-dioxo-, (αR,γS)-
  • LCZ696 impurities116
  • LCZ696 impurities518-12
  • Sabatrol calcium impurity O
  • 1639970-62-9
  • LCZ696