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Ald-Ph-PEG3-Azide

Product Name
Ald-Ph-PEG3-Azide
CAS No.
1807540-88-0
Chemical Name
Ald-Ph-PEG3-Azide
Synonyms
DF-PEG3-N3;ALD-PH-PEG3-N3;Ald-Ph-PEG3-Azide;CHO-Ph-PEG3-azide;CHO-Ph-CONH-PEG3-azide;Ald-Ph-amido-C2-PEG3-azide
CBNumber
CB13062307
Molecular Formula
C16H22N4O5
Formula Weight
350.38
MOL File
1807540-88-0.mol
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Ald-Ph-PEG3-Azide Property

solubility 
Soluble in DMSO, DCM, DMF
form 
Oil
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-22380
Product name
Ald-Ph-PEG3-azide
Purity
95%
Packaging
100mg
Price
$280
Updated
2021/12/16
BroadPharm
Product number
BP-22380
Product name
Ald-Ph-PEG3-azide
Purity
95%
Packaging
250mg
Price
$460
Updated
2021/12/16
BroadPharm
Product number
BP-22380
Product name
Ald-Ph-PEG3-azide
Purity
95%
Packaging
500mg
Price
$650
Updated
2021/12/16
BroadPharm
Product number
BP-22380
Product name
Ald-Ph-PEG3-azide
Purity
95%
Packaging
1g
Price
$990
Updated
2021/12/16
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Ald-Ph-PEG3-Azide Chemical Properties,Usage,Production

Description

Ald-Ph-PEG3-azide is a PEG reagent containing a benzaldehyde group and a terminal azide group. The benzaldehyde can react with primary amines. The azide can react with alkynes, DBCO and BCN moieties via Click Chemistry reactions.

Uses

Ald-Ph-amido-C2-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Ald-Ph-amido-C2-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

Ald-Ph-PEG3-Azide Preparation Products And Raw materials

Raw materials

Preparation Products

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Ald-Ph-PEG3-Azide Suppliers

Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
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View Lastest Price from Ald-Ph-PEG3-Azide manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
CHO-Ph-CONH-PEG3-azide 1807540-88-0
Price
US $0.00/mg
Min. Order
250mg
Purity
>95.00%
Supply Ability
250mg
Release date
2024-03-23