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5-Methyluridine

Product Name
5-Methyluridine
CAS No.
1463-10-1
Chemical Name
5-Methyluridine
Synonyms
RIBOTHYMIDINE;1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-5-MethylpyriMidine-2,4(1H,3H)-dione;1-(BETA-D-RIBOFURANOSYL)THYMINE;5-Me-U;5-Me-Ur;Methyluridine;5-methyuridine;ribosylthymine;5-methyl-uridin;THYMINERIBOSIDE
CBNumber
CB1322473
Molecular Formula
C10H14N2O6
Formula Weight
258.23
MOL File
1463-10-1.mol
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5-Methyluridine Property

Melting point:
183-184 °C(lit.)
Density 
1.576±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Methanol (Slightly, Heated, Sonicated), Water (Sparingly, Sonicated)
pka
9.55±0.10(Predicted)
form 
powder
color 
white
PH
9.7
λmax
267 (pH 1)；268 (pH 13)
InChI
InChI=1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1
InChIKey
DWRXFEITVBNRMK-JXOAFFINSA-N
SMILES
OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=O)[C@H](O)[C@@H]1O
CAS DataBase Reference
1463-10-1(CAS DataBase Reference)
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Safety

Hazard Codes 
T+
Risk Statements 
26/27/28
Safety Statements 
24/25
WGK Germany 
3
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R752002
Product name
5-METHYLURIDINE
Purity
AldrichCPR
Packaging
25MG
Price
$29.8
Updated
2024/03/01
Sigma-Aldrich
Product number
535893
Product name
5-Methyluridine
Purity
97%
Packaging
25g
Price
$89.3
Updated
2023/06/20
Sigma-Aldrich
Product number
535893
Product name
5-Methyluridine
Purity
97%
Packaging
100g
Price
$235
Updated
2023/06/20
TCI Chemical
Product number
M1405
Product name
5-Methyluridine
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$21
Updated
2024/03/01
TCI Chemical
Product number
M1405
Product name
5-Methyluridine
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$29
Updated
2024/03/01
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5-Methyluridine Chemical Properties,Usage,Production

Description

5-Methyluridine is a pyrimidine nucleoside and methylated form of uridine. It is the ribonucleoside counterpart to the deoxyribonucleoside thymidine, which lacks a hydroxyl group at the 2' position. 5-Methyluridine contains a thymine base joined to a ribose pentose sugar. It is an endogenous methylated nucleoside found in human fluids. In cells, 5-methyluridine is present in tRNA, formed during its post-transcriptional modification by the methylation of uridine.

Chemical Properties

White Powder

Uses

A primary degradation product of tRNA, an urinary nucleoside as biological marker for patients with colorectal cancer.
It enhances the antitumor activity of 5-fluorouracil in a mouse Erlich solid carcinoma model and a P388 murine leukemia model. It has been used to characterize the activity of a variety of enzymes, including uridine nucleosidase.

Definition

ChEBI: Ribothymidine is a methyluridine having a single methyl substituent at the 5-position on the uracil ring. It has a role as a human metabolite, an Escherichia coli metabolite and an antigen.

5-Methyluridine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Methyluridine Suppliers

Americas 1 Belgium 1 Canada 4 China 344 Europe 3 Germany 8 India 19 Italy 1 Japan 2 Russia 1 Slovakia 1 South Korea 1 Switzerland 3 The Netherlands 1 United Kingdom 16 United States 52 Global 458
PMC Chemicals
Tel
--
Fax
--
Email
phil_conway24@hotmail.com
Country
The Netherlands
ProdList
265
Advantage
43
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View Lastest Price from 5-Methyluridine manufacturers

Xinxiang Aurora Biotechnology Co.,Ltd.
Product
5-Methyluridine 1463-10-1
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
98%
Supply Ability
20Ton
Release date
2024-10-31
WUHAN FORTUNA CHEMICAL CO., LTD
Product
5-Methyluridine 1463-10-1
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
1000KGS
Release date
2021-07-02
Hebei Weibang Biotechnology Co., Ltd
Product
5-Methyluridine 1463-10-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-05

1463-10-1, 5-MethyluridineRelated Search:

5-Methyluridine 2,2'β-Oxy-2-deoxo-2,3-didehydro-2'-deoxy-5-methyluridine,2,2'-ANHYDRO-5-METHYLURIDINE,O2,2'-Anhydro-5-methyluridine 2'-DEOXY-2'-FLUORO-5-METHYLURIDINE DMT-2'O-Methyl-rU Phosphoramidite 2'-C-Methyluridine 2'-O-METHYL-5-METHYLURIDINE,5-METHY-5-METHYLURIDINE 2'-O-METHYLURIDINE,2''-O-METHYLURIDINE CRYSTALLINE 3-METHYLURIDINE Uridine THYMIDINE 5'-MONOPHOSPHATE, [2-14C] DISODIUM SALT (AA-UTP) SODIUM SALT 5-METHYL-[1'-13C]URIDINE HT MEDIA SUPPLEMENT AMINOALLYL UTP 5'-O-(DIMETHOXYTRITYL)-2'-O-METHYL-5-METHYLURIDINE FLUORESCEIN-12-UTP 5-formyloxymethyluridine THYMIDINE-3',5'-DIPHOSPHATE, DISODIUM SALT

  • 5-methyl-uridin
  • 5-methyuridine
  • 5-Methyluridine (Patent )
  • THYMINERIBOSIDE
  • URIDINE, 5-METHYL-
  • 5-METHYLURIDINE(5-Methyl-1-ˉ-ribofuranosyl uracil
  • 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
  • 5-methyluridine/ribothymidine
  • ribosylthymine/5-methyluridine
  • 5-methyluridine (produced by synthesis)
  • Methyluridine
  • 5-Me-U
  • 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)oxolan-2-yl]-5-Methyl-1,2,3,4-tetrahydropyriMidine-2,4-dione
  • RibosylthyMine(5-Methyluridine,RibothyMidine)
  • 1-β-D-Ribofuranosylthymine
  • 5-Methyl-1-β-D-ribofuranosyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
  • 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-quinone
  • 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-5-MethylpyriMidine-2,4(1H,3H)-dione
  • 5-Methyluridine, >=99%
  • 5-Methyluridine≥ 99% (HPLC)
  • 5-METHYLURIDINE
  • 5-METHYL-D-URIDINE
  • 5-METHYL-1-BETA-D-RIBOFURANOSYL URACIL
  • 1-(BETA-D-RIBOFURANOSYL)THYMIDINE
  • 1-(BETA-D-RIBOFURANOSYL)THYMINE
  • BETA-D-THYMINE RIBOSIDE
  • BETA-RIBOFURANOSIDE
  • ribosylthymine
  • RIBOTHYMIDINE
  • 5-Me-Ur
  • 5-Methyluridine&gt
  • 5-Methyluridine USP/EP/BP
  • 5-Methyluridine extrapure, 98%
  • 5-Methyluridine, RNA modified ribo-nucleoside m5U
  • 5-Methyfuridine
  • 1463-10-1
  • 1436-10-1
  • 1463-10-3
  • C10H14N2O6
  • Specialty Synthesis
  • Nucleosides
  • Oligonucleotide Synthesis
  • Nucleosides, Nucleotides, Oligonucleotides
  • Nucleoside Analogs
  • BioChemical
  • Biochemicals and Reagents
  • Carbohydrates & Derivatives
  • Heterocycles
  • Biochemistry
  • Nucleosides and their analogs
  • Nucleosides, Nucleotides & Related Reagents
  • Bases & Related Reagents
  • Nucleotides
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Miscellaneous Biochemicals
  • Nucleotides and Nucleosides
  • bc0001