ALPHA-BUNGAROTOXIN
- Product Name
- ALPHA-BUNGAROTOXIN
- CAS No.
- 11032-79-4
- Chemical Name
- ALPHA-BUNGAROTOXIN
- Synonyms
- α-BuTX;ALPHA-BGT;ALPHA-BUTX;α-Bungotoxin;A-BUNGAROTOXIN;α-Bungarotoxin;ALPHA-BUNGAROTOXIN;TIANFU-CHEM - ALPHA-BUNGAROTOXIN;M.W. 7984.14 C338H529N97O105S11;BUNGARUS MULTICINCTUS TOXIN, ALPHA
- CBNumber
- CB1331318
- Molecular Formula
- C50H70O14
- Formula Weight
- 895.0824
- MOL File
- 11032-79-4.mol
ALPHA-BUNGAROTOXIN Property
- storage temp.
- −20°C
- solubility
- Soluble in sterile water
- form
- solid
- color
- white
- Water Solubility
- Soluble in water
- Sequence
- Ile-Val-Cys-His-Thr-Thr-Ala-Thr-Ser-Pro-Ile-Ser-Ala-Val-Thr-Cys-Pro-Pro-Gly-Glu-Asn-Leu-Cys-Tyr-Arg-Lys-Met-Trp-Cys-Asp-Ala-Phe-Cys-Ser-Ser-Arg-Gly-Lys-Val-Val-Glu-Leu-Gly-Cys-Ala-Ala-Thr-Cys-Pro-Ser-Lys-Lys-Pro-Tyr-Glu-Glu-Val-Thr-Cys-Cys-Ser-Thr-Asp-Lys-Cys-Asn-Pro-His-Pro-Lys-Gln-Arg-Pro-Gly (Disulfide bridge: Cys3-Cys23;Cys16-Cys44;Cys29-Cys33;Cys48-Cys59;Cys60-Cys65)
- InChIKey
- LYTCVQQGCSNFJU-UHFFFAOYSA-N
- CAS DataBase Reference
- 11032-79-4
Safety
- WGK Germany
- 3
- RTECS
- QQ4495249
- Toxicity
- chicken,LD50,intramuscular,74ug/kg (0.074mg/kg),Toxicon. Vol. 7, Pg. 89, 1969.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P322Specific measures (see …on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 203980
- Product name
- α-Bungarotoxin,
- Packaging
- 1mg
- Price
- $214
- Updated
- 2025/07/31
- Product number
- 16385
- Product name
- α-Bungarotoxin
- Purity
- ≥99%
- Packaging
- 1mg
- Price
- $149
- Updated
- 2021/12/16
- Product number
- 2133
- Product name
- alpha-Bungarotoxin
- Packaging
- 1
- Price
- $187
- Updated
- 2021/12/16
- Product number
- B6950
- Product name
- α-Bungarotoxin
- Packaging
- 1mg
- Price
- $207
- Updated
- 2021/12/16
- Product number
- TOX0000441
- Product name
- ALPHA-BUNGAROTOXIN
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.36
- Updated
- 2021/12/16
ALPHA-BUNGAROTOXIN Chemical Properties,Usage,Production
Chemical Properties
Single polypeptide weight; molecular weight of 8000.
Definition
A protein that binds specifically to acetylcholine receptors.
General Description
Blocks neuromuscular transmission by irreversible binding to motor end-plate acetylcholine receptor (Kd = 1 pM to 1 nM) but does not depress acetylcholine release from motor nerve endings. Blocks nicotine-induced increase of intracellular Ca2+ in PC12 cells (IC50 = 310 nM), and prevents opening of nicotinic receptor-associated ion channels. Reconstitution experiments in Xenopus oocytes have shown the effects of α-bungarotoxin on neuronal nAChR to be highly specific for the α7-subtype (IC50 = 1.6 nM), but not for the α3β4-subtype (IC50 >3 μM).
Hazard
Nuerotoxic.
Biochem/physiol Actions
Product does not compete with ATP.
storage
-20°C (desiccate)
ALPHA-BUNGAROTOXIN Preparation Products And Raw materials
Raw materials
Preparation Products
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