ChemicalBook > CAS DataBase List > GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN

GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN

Product Name
GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN
CAS No.
107444-51-9
Chemical Name
GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN
Synonyms
MKC253;GLP-17-3;Glp-I (7-36);GLP-1 [7-36];GLP-1(7-36), >98%;GLP-1-(7-36) amide;GLP-1(7-36) acetate;Human GLP-1 (7-36)-NH2;GLP-1 (7-36) or (7-37);GLP-1(7-37), IRP peptide
CBNumber
CB1335109
Molecular Formula
C149H226N40O45
Formula Weight
3297.68
MOL File
107444-51-9.mol
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GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN Property

Density 
1.47
RTECS 
LZ3980060
storage temp. 
−20°C
solubility 
Soluble in DMSO
form 
powder
Water Solubility 
Soluble in water (1 mg/ml).
InChIKey
DTHNMHAUYICORS-KTKZVXAJSA-N
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
G8147
Product name
Glucagon-Like Peptide I Amide Fragment 7-36 human
Purity
≥97% (HPLC), powder
Packaging
0.1mg
Price
$232
Updated
2024/03/01
Sigma-Aldrich
Product number
G8147
Product name
Glucagon-Like Peptide I Amide Fragment 7-36 human
Purity
≥97% (HPLC), powder
Packaging
1mg
Price
$1150
Updated
2024/03/01
Alfa Aesar
Product number
J66197
Product name
Glucagon-Like Peptide-1 (7-36) amide, human
Packaging
0.5mg
Price
$180
Updated
2023/06/20
Alfa Aesar
Product number
J66197
Product name
Glucagon-Like Peptide-1 (7-36) amide, human
Packaging
1mg
Price
$262
Updated
2023/06/20
Cayman Chemical
Product number
15069
Product name
GLP-1 (7-36) amide
Packaging
1mg
Price
$276
Updated
2021/12/16
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GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN Chemical Properties,Usage,Production

Uses

Diabetes?II?-?not?yet?an?approved?application

Uses

Glucagon-Like Peptide-1 is used as a Effector in the hormonal control of insulin secretion. The peptide fragment is secreted from the lower small intestine. Its action is mediated by receptors expressed by the endocrine pancreatic B-cells.

Uses

Glucagon-Like Peptide (GLP) I Amide Fragment 7-36 human has been used as a GLP-1 receptor agonist:

  • in lysate transfer cyclic adenosine monophosphate (cAMP) assay to test its effect on adenylyl cyclase activity
  • to pre-treat the human umbilical vein endothelial cells (HUVECs) to monitor its effect on hyperpermeability in endothelial cell (EC) monolayers and changes with the actin cytoskeleton
  • to test its inhibitory effect on vascular endothelial growth factor-A (VEGFA) based vasodilation in rat mesenteric arteries

General Description

Glucagon-like peptide 1 (GLP-1) peptide is obtained from proglucagon and is metabolically inactive. However, it is processed to two smaller amide forms, namely GLP-1 (7-37) amide and GLP-1 (7-36) amide. It is a natural gastrointestinal peptide.

Biochem/physiol Actions

GLP-1 (glucagon-like peptide 1) (7-36) amide is a potent insulinotropic peptide, which initiates the glucose-induced insulin release after meals or oral glucose intake. It has an anti-diabetogenic effect and thus, might have use in the treatment of non-insulin dependent diabetes mellitus.

storage

Store at -20°C

GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN Preparation Products And Raw materials

Raw materials

Preparation Products

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GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN Suppliers

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View Lastest Price from GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN 107444-51-9
Price
US $70.00-700.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-02
Hebei Mujin Biotechnology Co.,Ltd
Product
GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN 107444-51-9
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-06-01
Zhuozhou Wenxi import and Export Co., Ltd
Product
GLP-1 (7-36) amide 107444-51-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11

107444-51-9, GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMANRelated Search:

GLUCAGON-37 (HUMAN, MOUSE, RAT) GLP-1 (7-37) Growth hormone releasing peptide Pralmorelin Glucagon GLP-1 (MET(O)27)-GLUCAGON (1-29) (HUMAN, BOVINE, PORCINE) GLUCAGON-LIKE PEPTIDE I FRAGMENT 1-36 AMIDE HUMAN Bivalirudin Aviptadil Argipressine Calcitonin salmon Taspoglutide H-TYR-GLY-GLY-PHE-MET-OH Vapreotide Acetate GLP-1（Glucagon-like peptide-1）(7-36) glucagon-like peptide 1 L-Threonine, L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-α-aspartyl-2-methylalanyl-L-alanyl-L-arginyl-L-alanyl-L-α-glutamyl-L-α-glutamyl-L-phenylalanyl-L-valyl-L-lysyl-L-tryptophyl-L-leucyl-L-α-glutamy...

  • GLP-1(7-36), >98%
  • GLP-1(7-36),Human GLP-1-(7-36)-amide,Insulinotropin,MKC253,Glucagon-like Peptide 1 (7-36) amide, >98%
  • GLP-17-3
  • Human GLP-1-(7-36)-amide
  • HUMAN GLP-1-(7-36)-AMIDE; INSULINOTROPIN; MKC253; GLUCAGON-LIKE PEPTIDE 1 (7-36) AMIDE; GLP-1 (7-36) AMIDE
  • MKC253
  • GLP-1(7-36)/Glucagon-like peptide 1 (7-36) aMide (huMan, rat)
  • glucagon-likepeptidei(7-36
  • H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2 acetate salt
  • Human GLP-1 (7-36)-NH2
  • GLP-1(7-37), IRP peptide
  • Glucagon-Like Peptide (GLP) I (7-36), amide, human
  • GLP-1 (7-36) amide Acetate
  • GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat)|GLP-1 (7-36) amide(P1269)
  • PREPROGLUCAGON (98-127) AMIDE (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT) TRIFLUOROACETATE SALT
  • PREPROGLUCAGON 78-107 AMIDE
  • PREPROGLUCAGON (78-107) AMIDE (HUMAN)
  • PROGLUCAGON (78-107) AMIDE (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT) TRIFLUOROACETATE SALT
  • GLP-1(7-36)，Glucagon-Like Peptide I Amide Fragment 7-36 human
  • Glucagon-Like Peptide 1 (7-36) aMide (huMan, bovine, guinea pig, Mouse, rat), Preproglucagon (98-127) aMide (huMan, bovine, guinea pig, Mouse, rat), Proglucagon (78-107) aMide (huMan, bovine, guinea pig, Mouse, rat)
  • GLP-1 (7-36) or (7-37)
  • Glucagon-like peptide 1 (7-36) amide (human, rat)
  • GLP-1 (7-36) aMide (huMan, bovine, guinea pig, Mouse, rat) Glucagon-Like Peptide 1 (7-36) aMide (huMan, bovine, guinea pig, Mouse, rat), Preproglucagon (98-127) aMide (huMan, bovine, guinea pig, Mouse, rat), Proglucagon (78-107) aMide (huMan, bovine, guin
  • Glucagon-like peptide 1 (7-36) (huMan, rat, Mouse)
  • M.W. 3297.67 C149H226N40O45
  • GLP-1-(7-36) amide
  • Glp-I (7-36)
  • Glucagon-related peptide 1 (rana catesbeiana), 3-L-glutamic acid-10-L-valine-16-glycine-17-L-glutamine-23-L-isoleucine-24-L-alanine-27-L-valine-30-L-argininamide-31-de-L-proline-32-de-L-lysine-
  • HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-NH2
  • H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-NH2
  • HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2
  • GLP-1 [7-36]
  • GLP-1 (7-36) AMIDE (HUMAN)
  • GLP-1 (7-36) AMIDE (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT) TRIFLUOROACETATE SALT
  • GLP-1 (HUMAN, 7-36 AMIDE) (BOVINE, CANINE, RAT, GUINEA PIG)
  • GLUCAGON-LIKE PEPTIDE-1 [7-36]
  • GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN
  • GLUCAGON-LIKE PEPTIDE 1 (7-36) AMIDE (HUMAN)
  • GLUCAGON-LIKE PEPTIDE 1 (7-36) AMIDE (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT) TRIFLUOROACETATE SALT
  • GLUCAGON-LIKE PEPTIDE 1 (7-36) AMIDE (HUMAN, RAT, MOUSE)
  • GLUCAGON LIKE PEPTIDE-I (7-36) AMIDE, HUMAN
  • GLUCAGON-LIKE PEPTIDE 1 (HUMAN, 7-36 AMIDE) (BOVINE, CANINE, RAT, GUINEA PIG)
  • glucagon-like peptide i amide fragment 7-36 human
  • GLP-1(7-36) acetate
  • GLP-1 (7-36) AMIDE (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
  • GLP-1 (7-36) amide (human, bovine, gp, mouse, rat)
  • L-Argininamide, L-histidyl-L-alanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysyl...
  • GLP-1(7-36)?amide impurity
  • GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN USP/EP/BP
  • TIANFU CHEM GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN
  • Glucagon-Like Peptide I (7-36), amide, hum
  • MKC 253|||Human GLP-1-(7-36)-amide|||Glucagon-like Peptide 1 (7-36) amide|||Glucagon-Like Peptide (GLP) I (7-36), amide, human|||GLP-1(7-36)|||GLP-1-(7-36)-amide
  • 107444-51-9
  • C149H226N40O45
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • Cytokines, Growth Factors and Hormones