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LYN PEPTIDE INHIBITOR

Product Name
LYN PEPTIDE INHIBITOR
CAS No.
222018-18-0
Chemical Name
LYN PEPTIDE INHIBITOR
Synonyms
LYN PEPTIDE INHIBITOR;M.W. 2370.91 C115H184N30O24;L-Prolinamide, N-(1-oxooctadecyl)-L-tyrosylglycyl-L-tyrosyl-L-arginyl-L-leucyl-L-arginyl-L-arginyl-L-lysyl-L-tryptophyl-L-α-glutamyl-L-α-glutamyl-L-lysyl-L-isoleucyl-L-prolyl-L-asparaginyl-
CBNumber
CB1355822
Molecular Formula
C115H184N30O24
Formula Weight
2370.92
MOL File
222018-18-0.mol
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LYN PEPTIDE INHIBITOR Property

Density 
1.39±0.1 g/cm3(Predicted)
Sequence
Stearoyl-Tyr-Gly-Tyr-Arg-Leu-Arg-Arg-Lys-Trp-Glu-Glu-Lys-Ile-Pro-Asn-Pro-NH2
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
2265
Product name
Lynpeptideinhibitor
Packaging
1
Price
$371
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0004504
Product name
LYN PEPTIDE INHIBITOR
Purity
95.00%
Packaging
5MG
Price
$495.72
Updated
2021/12/16
ApexBio Technology
Product number
B5285
Product name
Lynpeptideinhibitor
Packaging
1mg
Price
$549
Updated
2021/12/16
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LYN PEPTIDE INHIBITOR Chemical Properties,Usage,Production

Uses

Lyn peptide inhibitor is a potent and cell-permeable inhibitor of Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. Lyn peptide inhibitor blocks Lyn activation and inhibits the binding of Lyn tyrosine kinase to?βc subunit of IL-3/GM-CSF/IL-5 receptors. Lyn peptide inhibitor can be used for study of ?asthma, allergic, and other eosinophilic disorders[1].

IC 50

IL-5; IL-3

References

[1] T Adachi, et al. The mapping of the Lyn kinase binding site of the common beta subunit of IL-3/granulocyte-macrophage colony-stimulating factor/IL-5 receptor. J Immunol. 1999 Feb 1;162(3):1496-501. PMID:9973406
[2] T Adachi, et al. A novel Lyn-binding peptide inhibitor blocks eosinophil differentiation, survival, and airway eosinophilic inflammation. J Immunol. 1999 Jul 15;163(2):939-46. PMID:10395690

LYN PEPTIDE INHIBITOR Preparation Products And Raw materials

Raw materials

Preparation Products

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LYN PEPTIDE INHIBITOR Suppliers

China 18 Europe 1 Germany 2 United Kingdom 1 United States 7 Global 29
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
BIOTREND Chemicals AG
Tel
--
Fax
--
Email
info@biotrend.ch
Country
Germany
ProdList
1250
Advantage
62

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  • LYN PEPTIDE INHIBITOR
  • M.W. 2370.91 C115H184N30O24
  • L-Prolinamide, N-(1-oxooctadecyl)-L-tyrosylglycyl-L-tyrosyl-L-arginyl-L-leucyl-L-arginyl-L-arginyl-L-lysyl-L-tryptophyl-L-α-glutamyl-L-α-glutamyl-L-lysyl-L-isoleucyl-L-prolyl-L-asparaginyl-
  • 222018-18-0
  • C115H184N30O24
  • Protein Kinase