ATP disodium salt

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ATP disodium salt

Product Name: ATP disodium salt
CAS No.: 987-65-5
Chemical Name: ATP disodium salt
Synonyms: ADENOSINE TRIPHOSPHATE DISODIUM;ATP-NA2;ATP DISODIUM SALT;ADENOSINE TRIPHOSPHATE, DISODIUM SALT;ATP 2NA;ATP DISODIUM;Adenosine 5'-triphosphate disodium salt;Adetide;551.145;adetphos
CBNumber: CB1360204
Molecular Formula: C10H17N5NaO13P3
Formula Weight: 531.18
MOL File: 987-65-5.mol

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ATP disodium salt Property

Melting point:: 188～190℃
Density: 1.85 at 20℃
vapor pressure: 0.1Pa at 20-50℃
storage temp.: -20°C
solubility: H₂O: 50 mg/mL
form: crystalline
color: White powder
PH Range: 2.5 - 3.5
Water Solubility: Soluble in water
Merck: 155
InChIKey: TTWYZDPBDWHJOR-IDIVVRGQSA-L
LogP: -2.66 at 24℃ and pH7
Surface tension: 67.86mN/m at 1.019g/L and 20℃
CAS DataBase Reference: 987-65-5(CAS DataBase Reference)
EPA Substance Registry System: Adenosine 5'-(tetrahydrogen triphosphate), disodium salt (987-65-5)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-24/25-36-26
WGK Germany: 3
RTECS: AU7417000
F: 10-21
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A6559
Product name: Adenosine 5′-triphosphate disodium salt solution
Purity: Crystalline ATP, HPLC purified, aqueous solution for RNA transcription
Packaging: 25μmol
Price: $123
Updated: 2024/03/01

Sigma-Aldrich

Product number: 119125
Product name: Adenosine 5?-Triphosphate, Disodium, Trihydrate, Low Metals Grade - CAS 987-65-5 - Calbiochem
Purity: Lowmetalsgrade.Speciallyprocessedtoreducelevelsofcontaminatingmetals.
Packaging: 1g
Price: $149
Updated: 2024/03/01

Cayman Chemical

Product number: 14498
Product name: Adenosine 5'-triphosphate (sodium salt)
Purity: ≥95%
Packaging: 5g
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 14498
Product name: Adenosine 5'-triphosphate (sodium salt)
Purity: ≥95%
Packaging: 10g
Price: $100
Updated: 2024/03/01

Cayman Chemical

Product number: 14498
Product name: Adenosine 5'-triphosphate (sodium salt)
Purity: ≥95%
Packaging: 25g
Price: $233
Updated: 2024/03/01

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ATP disodium salt Chemical Properties,Usage,Production

Description

ATP disodium salt (Adenosine 5'-triphosphate disodium salt) is an organic sodium salt. It consists of an ATP and a ({(2R,3S,4R,5R)-3,4-dihydroxy-5-(9h -purin-9-yl)oxolan-2-yl)methylphosphonatooxy)phosphonate. It has the role of providing a source of energy for cells and is a central component of energy storage and metabolism in the body. ATP disodium salt is an important endogenous signalling molecule in immunity and inflammation. It is an important component in the study of various physiological and biochemical processes. It is involved in a variety of cellular functions such as muscle contraction, nerve impulse transmission and membrane transport, making it a fundamental molecule for understanding biological mechanisms. It can also be used to photometrically determine Luc activity in cell extracts.

Chemical Properties

White powder

Uses

A metabolite of Adenosine (A280400), a multifunctional nucleoside triphosphate used in cells as a coenzyme of intracellular energy transfer. It transports chemical energy within cells for metabolism. ATP Disodium Salt is used in the synthetic preparation of ribose-modified deoxyadenosine bisphosphate analogues as P2Y1 receptor ligands.

Uses

In biochemical research. To inhibit enzymatic browning of raw edible plant materials, such as sliced apples, potatoes, etc.

Uses

Adenosine 5'-triphosphate disodium salt is a disodium salt form of adenosine-triphosphate which is a multifunctional nucleoside triphosphate.ATP (Adenosine-Triphosphate) transports chemical energy within cells for metabolism. ATP (Adenosine-Triphosphate) is produced by photophosphoryla.

Biological Activity

P2 purinoceptor agonist.

Biochem/physiol Actions

Adenosine 5′-triphosphate (ATP) is an important energy currency in all living organisms. It possesses high phosphate transfer potential. ATP is involved in several biological processes such as membrane transport, muscle contraction and synthesis, and degradation of biological molecules. It plays a role as an intracellular and extracellular signaling molecule in certain cellular processes such as cell motility, organ development, neurotransmission, and insulin secretion.

in vitro

ATP disodium salt (5mM; 1 hour) co-treatment with LPS (1 μg/ml) has a synergistic effect on activating the NLRP3 inflammasome in HGFs.
ATP disodium salt (2 mM; 0.5-24 hours) induces the secretion of interleukin 1β, KC, and MIP-2 from bone marrow-derived macrophages (BMDMs) in vitro in a caspase-1 activation-dependent manner.
ATP disodium salt stimulates cytokine and chemokine secretion, and inflammasome activation, directly and indirectly, induces in vitro neutrophil chemotaxis.

in vivo

ATP disodium salt (50 mg/kg; i.p.) protects mice against bacterial infection in vivo.
ATP disodium salt induces the secretion of IL1β, KC and MIP-2 and neutrophils recruitment in vivo.

storage

Store at -20°C

Toxicity evaluation

ATP disodium salt was administered by gavage to rats for 90 consecutive days at doses of 0 (control), 500, 1000, and 2000 mg kg BW?1·d?1 (n = 10 per sex/group). Subchronic administration of ATP was well tolerated at all dose levels. Body weights and feed consumption body weight gains were similar between ATP-treated and control rats. Minor differences were seen in hematology and blood chemistry; however, these changes were not dose-related and, therefore, not of biological or toxicological significance. Only one difference was observed in absolute organ weights; females of the high dose had increased kidney and increased relative kidney and liver weights; however, these differences were not seen in males nor appeared to be dose-related[1].

References

[1] Ralf Jger, John C. Fuller Jr., Martin Purpura . “Subchronic (90-Day) repeated dose toxicity study of disodium adenosine-5′-triphosphate in rats.” Regulatory Toxicology and Pharmacology 116 (2020): Article 104760.

ATP disodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from ATP disodium salt manufacturers

HangZhou RunYan Pharma Technology Co.,LTD.

Product: Adenosine 5'-triphosphate disodium salt,ATP-Na2; 5'-ATP-Na2 987-65-5
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 99.0%min. HPLC
Supply Ability: 10000
Release date: 2024-09-20

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Adenosine 5-Triphosphate Disodium Salt 987-65-5
Price: US $79.00-38.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-11-19

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Adenosine Disodium Triphosphate 987-65-5
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-11-28

987-65-5, ATP disodium saltRelated Search:

Ethylenediaminetetraacetic acid disodium salt Cyclic AMP Adenosine5'-(tetrahydrogen triphosphate), disodiuM salt, trihydrate (9CI) Sodium chloride Clodronate disodium Pamidronate disodium salt Dibutyryl adenosine cyclophosphate calcium Adenosine triphosphate Sodium Phosphate, Dibasic ADENOSINE 5'-TRIPHOSPHATE DISODIUM SAL& Cytidine 5'-triphosphate disodium salt Cytidine-5'-triphosphate disodium salt dihydrate ADENOSINE 5'-DIPHOSPHATE DI(MONOCYCLOHEXYLAMMONIUM) SALT Sodium Monofluorophosphate Adenosine-5'-diphosphate trilithium salt NADP sodium salt Guanosine-5'-triphosphate disodium salt Uridine-5'-triphosphoric acid trisodium salt Atp Disodium Salt

ADENOSINE TRIPHOSPHATE DISODIUM

ADENOSINE TRIPHOSPHATE, DISODIUM SALT

ADENYLPYROPHOSPHORIC ACID DISODIUM SALT

ADENOSINE-5'-TRIPHOSPHATE HYDRATE DISODIUM SALT

ADENOSINE-5'-TRIPHOSPHATE NA2-SALT

ADENOSINE-5'-TRIPHOSPHORIC ACID, DISODIUM

ADENOSINE-5'-TRIPHOSPHORIC ACID DISODIUM DIHYDROGEN SALT

ADENOSINE 5'-TRIPHOSPHORIC ACID DISODIUM SALT

ADENOSINE-5'-TRIPHOSPHATE TRIHYDRATE DISODIUM SALT

Adenosine -5'- Triphosphate Disodium Salt（ATP-Na2）

disodiumatp

disodiumdihydrogenatp

adenoshine-5'-triphosphate di-sodium salt

ADENOSINE 5'-TRIPHOSPHATE DISODIUMGRADE II FROM

ADENOSINE 5'-TRIPHOSPHATE DISODIUMGRADE I FROM

ADENOSINE 5'-TRIPHOSPHATE DISODIUMSIGMAU LTRA FROM

ADENOSINE 5'-TRIPHOSPHATE DISODIUM CELL CULTURE TES

ADENOSINE-5'-TRIPHOSPHORIC ACID DISODIUM SALT BIOSYNTH

Adenosine5-TriphosphoricAcidDisodiumSalt(Atp)

Atp,Disodium,Trihydrate

ADENOSINE-5-DIPHOSPHORIC ACID DI SODIUIM SALT (A.T.P.)

Adenosintriphosphat

Adenosintriphosphate

Adenosine 5'-triphosphate disodiuM salt SynonyMs ATP disodiuM salt

ADENOSINE TRIPHOSPHATE DISODIUM SALT (ATP NA)

5'ADENOSINETRIPHOSPHORIC ACID DISODIUM SALT HYDRATE

Adenosine-5'-triphosphoric

adenosine 5'-triphosphate disodium salt solution

Adenosine Disodium Triphosphate Tablets

Adenosine 5'-(tetrahydrogen triphosphate), sodium salt (1:2)

HEPES FREE ACID HIGH PURITY GRADE

ATPNa2 ( Adenosine-5'-triphosphate,disodium salt,trihydrate)

Adenosine 5?-Triphosphate, Disodium, Trihydrate, Low Metals Grade

5'-ATP,Na3

Adenosine Triphosphate Disdium Salt

ADENOSINE-5'-PHOSPHORIC ACID, DISODIUM SALT

ADENOSINE 5'-(TETRAHYDROGEN TRIPHOSPHATE) DISODIUM

ADENOSINE 5'-(TETRAHYDROGEN TRIPHOSPHATE) DISODIUM SALT

ADENOSINE 5'-TRIPHOSPHATE (ATP) STANDARD DISODIUM SALT

ADENOSINE 5'-TRIPHOSPHATE, DISODIUM

ADENOSINE 5'-TRIPHOSPHATE DISODIUM SALT TRIHYDRATE

ADENOSINE 5'-TRIPHOSPHATE, DISODIUM, TRIHYDRATE

5'-ADENOSINETRIPHOSPHORIC ACID DISODIUM SALT

5'-ATP 2NA 3H2O

ATP 2NA

ATP, 2NA, TRIHYDRATE

ATP DISODIUM

ATP DISODIUM SALT

ATP DISODIUM SALT TRIHYDRATE

ATP-NA2

ATP, NA2H2

ATP TRIHYDRATE

ATP TRIHYDRATE DISODIUM SALT

adetphos

disodiumadenosine5’-triphosphate

disodiumadenosinetriphosphate

Adenosine 5'-triphosphate disodium salt

ADENOSINE TRIPHOSPHATE DISODIUM (ATP DISODIUM SALT)