(R)-N-Boc-3-Amino-3-phenylpropanoic acid
Uses- Product Name
- (R)-N-Boc-3-Amino-3-phenylpropanoic acid
- CAS No.
- 161024-80-2
- Chemical Name
- (R)-N-Boc-3-Amino-3-phenylpropanoic acid
- Synonyms
- Boc-R-PHA;Boc-b-Phe-OH;Boc-β-Phe-OH;Boc-R-(γ)-Phe;BOC-BETA-PHE-OH;(R)-Boc-β-Phe-OH;BOC-PHG-(C*CH2)OH;DL-N-Boc-β-Phe-OH;(R)-Boc-beta-Phe-OH;RARECHEM AK PT B077
- CBNumber
- CB1368088
- Molecular Formula
- C14H19NO4
- Formula Weight
- 265.31
- MOL File
- 161024-80-2.mol
(R)-N-Boc-3-Amino-3-phenylpropanoic acid Property
- Melting point:
- 123.4 °C
- Boiling point:
- 408.52°C (rough estimate)
- Density
- 1.1356 (rough estimate)
- refractive index
- 1.5110 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 4.32±0.10(Predicted)
- form
- Powder
- color
- White
- BRN
- 5404389
- InChI
- InChI=1/C14H19NO4/c1-14(2,3)19-13(18)15-11(9-12(16)17)10-7-5-4-6-8-10/h4-8,11H,9H2,1-3H3,(H,15,18)(H,16,17)/t11-/s3
- InChIKey
- JTNQFJPZRTURSI-LBPXTSNRNA-N
- SMILES
- [C@H](C1C=CC=CC=1)(CC(=O)O)NC(=O)OC(C)(C)C |&1:0,r|
- CAS DataBase Reference
- 161024-80-2(CAS DataBase Reference)
Safety
- Safety Statements
- 24/25
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29242990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
N-Bromosuccinimide Price
- Product number
- 09794
- Product name
- Boc-β-Phe-OH
- Purity
- ≥96.0% (HPLC)
- Packaging
- 1g
- Price
- $762
- Updated
- 2023/06/20
- Product number
- 265317
- Product name
- Boc-L-beta-phenylalanine
- Packaging
- 500mg
- Price
- $347
- Updated
- 2021/12/16
- Product number
- B621123
- Product name
- (R)-N-Boc-3-amino-3-phenylpropanoicAcid
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FB49766
- Product name
- Boc-L-beta-phenylalanine
- Packaging
- 500mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- B099
- Product name
- Boc-L-β-phenylalanine
- Packaging
- 5g
- Price
- $110
- Updated
- 2021/12/16
(R)-N-Boc-3-Amino-3-phenylpropanoic acid Chemical Properties,Usage,Production
Uses
(R)-Boc-beta-phenylalanine is an amino acid derivative that can be used as an organic intermediate.
Chemical Properties
white powder
Synthesis
(R)-3-Amino-3-phenylpropionic acid (2.1 g, 12.7 mmol, 1.0 equiv.) and NaHCO3 (1.6 g, 19 ) were dissolved in water (30 mL). mmol, 1.5 equiv.) were dissolved in water (30 mL). Dioxane (30 mL) and [(CH3)3CO2C]2O (4.1 g, ) were dissolved in water (30 mL). 19 mmol, 1.5 equiv.) were added to the reaction mixture. The solution was stirred at room temperature for 8 hours. The solution was analyzed by TLC (SiO2, 50/25/25 The complete conversion of (R)-3-amino-3-phenylpropionic acid was confirmed by TLC (SiO2, 50/25/25 n-BuOH/HOAc/H2O). The solvent was removed by rotary evaporation. Distribute the crude mixture between HCl (1%) and EtOAc . the crude mixture was partitioned between HCl (1%) and EtOAc . The aqueous layer was extracted with EtOAc. The combined organic extracts were dried with Na2SO4. The solvent was filtered and concentrated. The crude was purified by column chromatography, eluting with 10% , CH3OH/DCM, and then with 10% . CH3OH/DCM to give (R)-Boc-beta-phenylalanine.
(R)-N-Boc-3-Amino-3-phenylpropanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (R)-N-Boc-3-Amino-3-phenylpropanoic acid manufacturers
- Product
- (R)-N-Boc-3-Amino-3-phenylpropanoic acid 161024-80-2
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- JD 348
- Release date
- 2019-09-01