Uses Biodegradation
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N-Methyl-4-nitroaniline

Uses Biodegradation
Product Name
N-Methyl-4-nitroaniline
CAS No.
100-15-2
Chemical Name
N-Methyl-4-nitroaniline
Synonyms
Nitronaniline;4-nitro-n-methylaniline;Methyl-4-nitroaniline;N-methy-4-nitroanline;Intedanib Impurity 10;N-Methyl-p-nitraniline;Miglinide intermediate;N-METHYL-P-NITROANILINE;N-METHYL-4-NITROANILINE;P-NITRO-N-METHYLANILINE
CBNumber
CB1387643
Molecular Formula
C7H8N2O2
Formula Weight
152.15
MOL File
100-15-2.mol
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N-Methyl-4-nitroaniline Property

Melting point:
149-151 °C(lit.)
Boiling point:
294.61°C (rough estimate)
Density 
1.2010
vapor density 
5.25 (vs air)
refractive index 
1.6276 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
0.56±0.12(Predicted)
color 
Yellow to Very Dark Yellow
Water Solubility 
<0.1 g/100 mL at 19 ºC
BRN 
637920
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey
XIFJZJPMHNUGRA-UHFFFAOYSA-N
CAS DataBase Reference
100-15-2(CAS DataBase Reference)
NIST Chemistry Reference
Benzenamine, N-methyl-4-nitro-(100-15-2)
EPA Substance Registry System
N-Methyl-p-nitroaniline (100-15-2)
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Safety

Hazard Codes 
T,Xi
Risk Statements 
23/24/25-33-36/37/38
Safety Statements 
28-36/37/39-45-26
RIDADR 
2811
WGK Germany 
3
Hazard Note 
Highly Toxic/Irritant
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29214200
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
269638
Product name
N-Methyl-4-nitroaniline
Purity
97%
Packaging
25g
Price
$51.5
Updated
2024/03/01
Sigma-Aldrich
Product number
269638
Product name
N-Methyl-4-nitroaniline
Purity
97%
Packaging
100g
Price
$161
Updated
2024/03/01
Alfa Aesar
Product number
A15548
Product name
N-Methyl-4-nitroaniline, 97%
Packaging
5g
Price
$37.3
Updated
2023/06/20
Alfa Aesar
Product number
A15548
Product name
N-Methyl-4-nitroaniline, 97%
Packaging
25g
Price
$133
Updated
2023/06/20
Alfa Aesar
Product number
A15548
Product name
N-Methyl-4-nitroaniline, 97%
Packaging
100g
Price
$439
Updated
2023/06/20
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N-Methyl-4-nitroaniline Chemical Properties,Usage,Production

Uses

N-methyl-4-nitroaniline is a stabilizer for gunpowder, a desensitizing agent for molten cast explosive TNAZ, a widely used organic intermediate, and N-methyl-4-nitroaniline can be used as a reference substance by its polarizing properties.
N-methyl-4-nitroaniline is an attractive candidate for its appealing capability to retain the nitrogen oxides, good thermal stability, and facile synthesis from abundant and inexpensive starting materials.

Biodegradation

N-Methyl-4-nitroaniline is used as an additive to lower the melting temperature of energetic materials in the synthesis of insensitive explosives. Although the biotransformation of N-Methyl-4-nitroaniline under anaerobic condition has been reported, its aerobic microbial degradation has not been documented yet. A soil microcosms study showed the efficient aerobic degradation of N-Methyl-4-nitroaniline by the inhabitant soil microorganisms.

Chemical Properties

brownish-yellow crystalline powder

Uses

N-Methyl-4-nitroaniline is a versatile reactant used in the synthesis of oxindoles using Pd-catalyzed cyclization of chloroacetanilides.

General Description

Brownish-yellow prisms with violet reflex (from ethanol) or yellow powder.

Air & Water Reactions

N-Methyl-4-nitroaniline may be sensitive to prolonged exposure to air. Insoluble in water.

Reactivity Profile

N-Methyl-4-nitroaniline has a vigorous exothermic reaction with carbaryl sulfate when heated above 167° F.

Fire Hazard

Flash point data for N-Methyl-4-nitroaniline are not available; however, N-Methyl-4-nitroaniline is probably combustible.

Purification Methods

Crystallise the aniline from aqueous EtOH. [Beilstein 12 H 714.]

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N-Methyl-4-nitroaniline Suppliers

P&S Chemicals
Tel
--
Fax
--
Email
info@pschemicals.com
Country
The Netherlands
ProdList
2724
Advantage
58
Specs
Tel
--
Fax
--
Email
info@specs.net
Country
The Netherlands
ProdList
6833
Advantage
70
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View Lastest Price from N-Methyl-4-nitroaniline manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
N-Methyl-4-nitroaniline 100-15-2
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-11-27
hebei hongtan Biotechnology Co., Ltd
Product
N-Methyl-4-nitroaniline 100-15-2
Price
US $30.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
3000kg
Release date
2024-05-14
Hebei Yanxi Chemical Co., Ltd.
Product
N-Methyl-4-nitroaniline 100-15-2
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-11-20

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