Boc-N-Me-Val-OH

Product Name: Boc-N-Me-Val-OH
CAS No.: 45170-31-8
Chemical Name: Boc-N-Me-Val-OH
Synonyms: Boc-N-me-Val;BOC-N-ME-VAL-OH;Boc-L-N-Me-Val-OH;BOC-MEVAL-OH;BOC-L-MEVAL-OH;BOC-N-ME-VALINE;)amino)-3-methyL;Boc-N-Me-L-Val-OH;N-Boc-N-methylvaline;BOC-N-METHYL-L-VALINE
CBNumber: CB1401257
Molecular Formula: C11H21NO4
Formula Weight: 231.29
MOL File: 45170-31-8.mol

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Boc-N-Me-Val-OH Property

Melting point:: 45-60°C
Boiling point:: 322.4±21.0 °C(Predicted)
alpha: -94 º (c=0.5% in ethanol)
Density: 1.069±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form: Solid
pka: 4.03±0.10(Predicted)
color: Off-White
optical activity: [α]20/D 94±3°, c = 0.5% in ethanol
BRN: 2646180
InChI: InChI=1S/C11H21NO4/c1-7(2)8(9(13)14)12(6)10(15)16-11(3,4)5/h7-8H,1-6H3,(H,13,14)/t8-/m0/s1
InChIKey: XPUAXAVJMJDPDH-QMMMGPOBSA-N
SMILES: C(O)(=O)[C@H](C(C)C)N(C(OC(C)(C)C)=O)C
CAS DataBase Reference: 45170-31-8(CAS DataBase Reference)

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Safety

WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29225090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.53085
Product name: Boc-N-Me-Val-OH
Purity: Novabiochem?
Packaging: 5G
Price: $135
Updated: 2024/03/01

Sigma-Aldrich

Product number: 15538
Product name: Boc-N-Me-Val-OH
Purity: ≥99.0% (TLC)
Packaging: 1g
Price: $39.44
Updated: 2024/03/01

Alfa Aesar

Product number: H62771
Product name: N-Boc-N-methyl-L-valine, 95%
Packaging: 1g
Price: $68.65
Updated: 2024/03/01

Alfa Aesar

Product number: H62771
Product name: N-Boc-N-methyl-L-valine, 95%
Packaging: 5g
Price: $292.65
Updated: 2024/03/01

Usbiological

Product number: 264718
Product name: Boc-N-methyl-L-valine
Packaging: 500mg
Price: $333
Updated: 2021/12/16

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Boc-N-Me-Val-OH Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

N-Boc-N-methyl-L-valine (Boc-N-Me-Val-OH) is an amino acid derived compound that functions as a useful pharmaceutical intermediate and also employed as a reagent used in organic synthesis. It is used in the synthesis of lactam analog of actinomycin D, a potential antitumor chemotherapeutic agent. It is also used to N-tert-Butoxycarbonyl-N-methyl-L-valine 4-ethynylanilide with 4-ethynylaniline[1].

Synthesis

To a solution of N-BOC-valine 1 (217 mg, 1 mmol) and iodomethane(1.42 g, 10 mmol) in anhydrous tetrahydrofuran (THF,20 mL) was added neat sodium hydride (240 mg, 10 mmol). The reaction mixture was stirred at room temperature for 24 hours. The mixture was then quenched with water (30 mL). The reaction mixture was extracted with ethyl acetate (EtOAc, 2 15 mL) and the aqueous solution was acidified to pH 3, after which it was extracted with EtOAc (3 20 mL). The combined organic phase was dried over anhydrous Na2SO4 and evaporated to afford the corresponding Boc-N-Me-Val-OH (thick colorless oil), 99% yield.

References

[1] Masashi Shiotsuki. “Molecular weight dependence of helical conformation of amino acid-based polyphenylacetylenes.” Journal of Polymer Science Part A: Polymer Chemistry 49 22 (2011): 4921–4925.

Boc-N-Me-Val-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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Boc-N-Me-Val-OH Suppliers

China 202 Europe 1 France 1 Germany 6 India 8 Japan 4 Switzerland 4 United Kingdom 9 United States 38 Global 273

Sichuan jiayinglai technology CO.,LTD

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Alabiochem Tech.Co., Ltd.

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Alfa Aesar

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Energy Chemical

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Capot Chemical Co., Ltd

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Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

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Jia Xing Isenchem Co.,Ltd

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View Lastest Price from Boc-N-Me-Val-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Boc-N-Me-Val-OH 45170-31-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2023-09-27

Shanghai Getian Industrial Co., LTD

Product: Boc-N-Me-Val-OH 45170-31-8
Price: US $28.00/box
Min. Order: 1box
Purity: 99%
Supply Ability: 20000
Release date: 2024-04-11

Zibo Hangyu Biotechnology Development Co., Ltd

Product: Boc-N-Me-Val-OH 45170-31-8
Price: US $65.00-650.00/KG
Min. Order: 1KG
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-10-25

45170-31-8, Boc-N-Me-Val-OHRelated Search:

Thiophanate-methyl Methylparaben Bensulfuron methyl N-Carbobenzyloxyglycine Kresoxim-methyl Boc-Aib-OH Sodium carboxymethyl cellulose N-Methyl-2-pyrrolidone 1-Methylimidazole 1-Methylpyrrolidine L-Valine Methyl acrylate N,N-Dimethylformamide PYRAZOPHOS N-Boc-L-valine Valine CARBONYL SULFIDE Methyl

BOC-N-METHYL-L-VAL-OH

Boc-N-me-Val

N-ALPHA-TERT-BUTYLOXYCABONYL-N-ALPHA-METHYL-L-VALINE

NALPHA-tert-Butoxycarbonyl-N-methyl-L-valine

N-[(tert-Butoxy)carbonyl]-N-methyl-L-valine

Boc-L-N-Me-Val-OH

(S)-2-((tert-Butoxycarbonyl)(Methyl)aMino)-3-Methylbutanoic acid

Boc-N-Me-Val-OH >=99.0% (TLC)

Boc-N-Me-L-Val-OH

(2S)-2-[[(tert-Butoxy)carbonyl](methyl)amino]-3-methylbutanoic acid

BOC-N-METHYL-L-VALINE

BOC-N-ME-VALINE

BOC-N-ME-VAL-OH

BOC-MEVAL-OH

BOC-N-ALPHA-METHYL-L-VALINE

BOC-L-MEVAL-OH

N-ALPHA-T-BOC-N-ALPHA-METHYL-L-VALINE

N-ALPHA-T-BUTOXYCARBONYL-N-ALPHA-METHYL-L-VALINE

N-ALPHA-T-BUTYLOXYCARBONYL-N-ALPHA-METHYL-L-VALINE

N-ALPHA-TERT-BUTYLOXYCARBONYL-N-ALPHA-METHYL-L-VALINE

N-BOC-N-METHYL-(L)-VALINE

Boc-N-methyl-L-valine≥ 99% (TLC)

(Tert-Butoxy)Carbonyl N-Me-Val-OH (Syrup)

N-(tert-Butoxycarbonyl)-N-methyl-L-valine&gt

(S)-2-((tert-ButoxycarbonyL

)amino)-3-methyL

L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl-

(2S)-3-methyl-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]butanoicaci

Boc-N-methyl-L-valine USP/EP/BP

N-Boc-N-methylvaline

Boc-N-α-Methyl-L-valine

Entecavir Impurity 133

45170-31-8

N-Methyl Amino Acids

Peptide Synthesis

Unnatural Amino Acid Derivatives

Specialty Synthesis

amino acids

Valine [Val, V]

N-Methyl Amino Acids

Boc-Amino acid series