Boc-N-Me-Val-OH

Product Name: Boc-N-Me-Val-OH
CAS No.: 45170-31-8
Chemical Name: Boc-N-Me-Val-OH
Synonyms: Boc-N-me-Val;BOC-N-ME-VAL-OH;Boc-L-N-Me-Val-OH;BOC-MEVAL-OH;BOC-L-MEVAL-OH;BOC-N-ME-VALINE;)amino)-3-methyL;Boc-N-Me-L-Val-OH;N-Boc-N-methylvaline;BOC-N-METHYL-L-VALINE
CBNumber: CB1401257
Molecular Formula: C11H21NO4
Formula Weight: 231.29
MOL File: 45170-31-8.mol

More

Less

Boc-N-Me-Val-OH Property

Melting point:: 45-60°C
Boiling point:: 322.4±21.0 °C(Predicted)
alpha: -94 º (c=0.5% in ethanol)
Density: 1.069±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form: Solid
pka: 4.03±0.10(Predicted)
color: Off-White
optical activity: [α]20/D 94±3°, c = 0.5% in ethanol
BRN: 2646180
InChI: InChI=1S/C11H21NO4/c1-7(2)8(9(13)14)12(6)10(15)16-11(3,4)5/h7-8H,1-6H3,(H,13,14)/t8-/m0/s1
InChIKey: XPUAXAVJMJDPDH-QMMMGPOBSA-N
SMILES: C(O)(=O)[C@H](C(C)C)N(C(OC(C)(C)C)=O)C
CAS DataBase Reference: 45170-31-8(CAS DataBase Reference)

More

Less

Safety

WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29225090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.53085
Product name: Boc-N-Me-Val-OH
Purity: Novabiochem?
Packaging: 5G
Price: $135
Updated: 2024/03/01

Sigma-Aldrich

Product number: 15538
Product name: Boc-N-Me-Val-OH
Purity: ≥99.0% (TLC)
Packaging: 1g
Price: $39.44
Updated: 2024/03/01

Alfa Aesar

Product number: H62771
Product name: N-Boc-N-methyl-L-valine, 95%
Packaging: 1g
Price: $68.65
Updated: 2024/03/01

Alfa Aesar

Product number: H62771
Product name: N-Boc-N-methyl-L-valine, 95%
Packaging: 5g
Price: $292.65
Updated: 2024/03/01

Usbiological

Product number: 264718
Product name: Boc-N-methyl-L-valine
Packaging: 500mg
Price: $333
Updated: 2021/12/16

More

Less

Boc-N-Me-Val-OH Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

N-Boc-N-methyl-L-valine (Boc-N-Me-Val-OH) is an amino acid derived compound that functions as a useful pharmaceutical intermediate and also employed as a reagent used in organic synthesis. It is used in the synthesis of lactam analog of actinomycin D, a potential antitumor chemotherapeutic agent. It is also used to N-tert-Butoxycarbonyl-N-methyl-L-valine 4-ethynylanilide with 4-ethynylaniline[1].

Synthesis

To a solution of N-BOC-valine 1 (217 mg, 1 mmol) and iodomethane(1.42 g, 10 mmol) in anhydrous tetrahydrofuran (THF,20 mL) was added neat sodium hydride (240 mg, 10 mmol). The reaction mixture was stirred at room temperature for 24 hours. The mixture was then quenched with water (30 mL). The reaction mixture was extracted with ethyl acetate (EtOAc, 2 15 mL) and the aqueous solution was acidified to pH 3, after which it was extracted with EtOAc (3 20 mL). The combined organic phase was dried over anhydrous Na2SO4 and evaporated to afford the corresponding Boc-N-Me-Val-OH (thick colorless oil), 99% yield.

References

[1] Masashi Shiotsuki. “Molecular weight dependence of helical conformation of amino acid-based polyphenylacetylenes.” Journal of Polymer Science Part A: Polymer Chemistry 49 22 (2011): 4921–4925.

Boc-N-Me-Val-OH Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Boc-N-Me-Val-OH Suppliers

China 213 Europe 1 France 1 Germany 6 India 8 Japan 4 Switzerland 4 United Kingdom 9 United States 37 Global 283

ChemPep, Inc.

Tel: +1 (888) 615-9178 / (561) 791-8787
Fax: +1 (561) 791-8728
Email: service@chempep.com
Country: United States
ProdList: 2138
Advantage: 57

HBCChem, Inc.

Tel: +1-510-219-6317
Fax: +1-650-486-1361
Email: sales@hbcchem.com
Country: United States
ProdList: 10648
Advantage: 60

Alabiotech Inc.

Tel: 001-619-354-5251
Fax: 001-855-855-6087
Email: sales@alabiotech-e.com
Country: United States
ProdList: 972
Advantage: 60

AbaChemScene

Tel: 732-484-9848
Fax: 888-484-5008
Email: sales@chemscene.com
Country: United States
ProdList: 3982
Advantage: 60

BOC Sciences

Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Country: United States
ProdList: 19741
Advantage: 58

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

United States Biological

Tel: --
Fax: --
Email: sales@advtechind.com
Country: United States
ProdList: 6075
Advantage: 58

ApexBio Technology

Tel: --
Fax: --
Email: sales@apexbt.com
Country: United States
ProdList: 6251
Advantage: 58

Peptides International, Inc.

Tel: --
Fax: --
Email: peptides@pepnet.com
Country: United States
ProdList: 555
Advantage: 72

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6962
Advantage: 56

AlliChem, LLC

Tel: --
Fax: --
Email: sales@allichemllc.com
Country: United States
ProdList: 6516
Advantage: 60

Alichem Inc.

Tel: --
Fax: --
Email: sales@alichem.com
Country: United States
ProdList: 6167
Advantage: 58

OChem Incorporation

Tel: --
Fax: --
Email: sales@ocheminc.com
Country: United States
ProdList: 6501
Advantage: 60

AAPPTEC

Tel: --
Fax: --
Email: info@aapptec.com
Country: United States
ProdList: 533
Advantage: 0

Chiral Management

Tel: --
Fax: --
Email: sales@chiralmanagement.com
Country: United States
ProdList: 1332
Advantage: 30

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

Combi-Blocks Inc.

Tel: --
Fax: --
Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

Chem-Impex International, Inc.

Tel: --
Fax: --
Country: United States
ProdList: 6730
Advantage: 64

Oakwood Products, Inc.

Tel: --
Fax: --
Email: sales@oakwoodchemical.com
Country: United States
ProdList: 6193
Advantage: 74

Ivy Fine Chemicals

Tel: --
Fax: --
Email: sales@ivychem.com
Country: United States
ProdList: 6493
Advantage: 58

Leonid Chemicals Private Limited

Tel: --
Fax: --
Email: careers@leonidchemicals.com
Country: United States
ProdList: 1700
Advantage: 43

INDOFINE Chemical Company, Inc.

Tel: --
Fax: --
Email: chemical@indofinechemical.com
Country: United States
ProdList: 6176
Advantage: 69

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

AK Scientific, Inc.

Tel: --
Fax: --
Email: sales@aksci.com
Country: United States
ProdList: 6347
Advantage: 65

APAC Pharmaceutical, LLC

Tel: --
Fax: --
Email: sales@apacpharma.com
Country: United States
ProdList: 6322
Advantage: 38

EMD Biosciences, Inc.

Tel: --
Fax: --
Email: technical@calbiochem.com
Country: United States
ProdList: 6529
Advantage: 66

Synthetech, Inc.

Tel: --
Fax: --
Email: customer@synthetech.com
Country: United States
ProdList: 628
Advantage: 68

Advanced Quality Scitech Inc.

Tel: --
Fax: --
Email: sales@advnacetechusa.com
Country: United States
ProdList: 238
Advantage: 30

BOSCHE SCIENTIFIC, LLC

Tel: --
Fax: --
Email: Sales@BoscheSci.com
Country: United States
ProdList: 6477
Advantage: 55

AnaSpec, Inc.

Tel: --
Fax: --
Email: service@anaspec.com
Country: United States
ProdList: 4871
Advantage: 77

ChemPacific Corporation

Tel: --
Fax: --
Email: sales@chempacific.com
Country: United States
ProdList: 6891
Advantage: 51

Advanced ChemTech

Tel: --
Fax: --
Country: United States
ProdList: 1606
Advantage: 69

Frontage Laboratories, Inc.

Tel: --
Fax: --
Email: rconnolly@frontagelab.com
Country: United States
ProdList: 199
Advantage: 67

More

Less

View Lastest Price from Boc-N-Me-Val-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Boc-N-Me-Val-OH 45170-31-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2023-09-27

Zibo Hangyu Biotechnology Development Co., Ltd

Product: Boc-N-Me-Val-OH 45170-31-8
Price: US $65.00-650.00/KG
Min. Order: 1KG
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-10-25

Shanghai Getian Industrial Co., LTD

Product: Boc-N-Me-Val-OH 45170-31-8
Price: US $28.00/box
Min. Order: 1box
Purity: 99%
Supply Ability: 20000box
Release date: 2024-06-03

45170-31-8, Boc-N-Me-Val-OHRelated Search:

Thiophanate-methyl Methylparaben Bensulfuron methyl N-Carbobenzyloxyglycine Kresoxim-methyl Boc-Aib-OH Sodium carboxymethyl cellulose N-Methyl-2-pyrrolidone 1-Methylimidazole 1-Methylpyrrolidine L-Valine Methyl acrylate N,N-Dimethylformamide PYRAZOPHOS N-Boc-L-valine Valine CARBONYL SULFIDE Methyl

BOC-N-METHYL-L-VAL-OH

Boc-N-me-Val

N-ALPHA-TERT-BUTYLOXYCABONYL-N-ALPHA-METHYL-L-VALINE

NALPHA-tert-Butoxycarbonyl-N-methyl-L-valine

N-[(tert-Butoxy)carbonyl]-N-methyl-L-valine

Boc-L-N-Me-Val-OH

(S)-2-((tert-Butoxycarbonyl)(Methyl)aMino)-3-Methylbutanoic acid

Boc-N-Me-Val-OH >=99.0% (TLC)

Boc-N-Me-L-Val-OH

(2S)-2-[[(tert-Butoxy)carbonyl](methyl)amino]-3-methylbutanoic acid

BOC-N-METHYL-L-VALINE

BOC-N-ME-VALINE

BOC-N-ME-VAL-OH

BOC-MEVAL-OH

BOC-N-ALPHA-METHYL-L-VALINE

BOC-L-MEVAL-OH

N-ALPHA-T-BOC-N-ALPHA-METHYL-L-VALINE

N-ALPHA-T-BUTOXYCARBONYL-N-ALPHA-METHYL-L-VALINE

N-ALPHA-T-BUTYLOXYCARBONYL-N-ALPHA-METHYL-L-VALINE

N-ALPHA-TERT-BUTYLOXYCARBONYL-N-ALPHA-METHYL-L-VALINE

N-BOC-N-METHYL-(L)-VALINE

Boc-N-methyl-L-valine≥ 99% (TLC)

(Tert-Butoxy)Carbonyl N-Me-Val-OH (Syrup)

N-(tert-Butoxycarbonyl)-N-methyl-L-valine&gt

(S)-2-((tert-ButoxycarbonyL

)amino)-3-methyL

L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl-

(2S)-3-methyl-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]butanoicaci

Boc-N-methyl-L-valine USP/EP/BP

N-Boc-N-methylvaline

Boc-N-α-Methyl-L-valine

Entecavir Impurity 133

45170-31-8

N-Methyl Amino Acids

Peptide Synthesis

Unnatural Amino Acid Derivatives

Specialty Synthesis

amino acids

Valine [Val, V]

N-Methyl Amino Acids

Boc-Amino acid series