6-ACETYL-7-DEACETYLFORSKOLIN

Product Name: 6-ACETYL-7-DEACETYLFORSKOLIN
CAS No.: 64657-21-2
Chemical Name: 6-ACETYL-7-DEACETYLFORSKOLIN
Synonyms: Coleol B;Coleonol B;Isoforsklin;Isoforskoli;ISOFORSKOLIN;Isoforskolin-RM;6-ACETYL-7-DEACETYLFORSKOLIN;FORSKOLIN, 6-ACETYL-7-DEACETYL-;Isoforskolin（ Coleonol B,Excolabdone C）;6-ACETYL-7-DEACETYLFORSKOLIN FROMCOLEUS FORSKOHLII
CBNumber: CB1431241
Molecular Formula: C22H34O7
Formula Weight: 410.5
MOL File: 64657-21-2.mol

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6-ACETYL-7-DEACETYLFORSKOLIN Property

Melting point:: 220-222 °C(Solv: chloroform (67-66-3); methanol (67-56-1))
Boiling point:: 524.5±50.0 °C(Predicted)
Density: 1.23±0.1 g/cm3(Predicted)
storage temp.: −20°C
solubility: Chloroform: Soluble; DMSO: Soluble
form: A solid
pka: 11.03±0.70(Predicted)
color: White to off-white
optical activity: [α]/D -8 to -5°, c =0.5 in chloroform-d

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Safety

Hazard Codes: Xn
Risk Statements: 21
Safety Statements: 36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H312Harmful in contact with skin

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2801
Product name: Isoforskolin
Purity: ≥95% (HPLC)
Packaging: 5MG
Price: $94.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML2801
Product name: Isoforskolin
Purity: ≥95% (HPLC)
Packaging: 25MG
Price: $314
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHL82566
Product name: Isoforskolin
Purity: phyproof? Reference Substance
Packaging: 10mg
Price: $873
Updated: 2024/03/01

Cayman Chemical

Product number: 11716
Product name: Isoforskolin
Purity: ≥98%
Packaging: 1mg
Price: $81
Updated: 2024/03/01

TRC

Product number: A172183
Product name: 6-Acetyl-7-deacetylforskolin
Packaging: 2.5mg
Price: $85
Updated: 2021/12/16

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6-ACETYL-7-DEACETYLFORSKOLIN Chemical Properties,Usage,Production

Uses

Iso-Forskolin is a byproduct in the synthesis of 9-Deoxyforskolin (D239935) from Coleus forskohlii, which is an adenylyl cyclase isoform activator; Antihypertensive.

Uses

6-Acetyl-7-deacetylforskolin is a bioactive constituents from the medical plant, Coleus forskohlii. Also, it has anticancer and glucosidase inhibition activities.

General Description

This substance is supplied with certified chromatographic purity. The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biological Activity

Isoforskolin is a naturally occurring diterpene with anti-inflammatory activity. It has been shown to downregulate the expression of proinflammatory compounds. In an experimental mouse model of Lyme Disease induced arthritis isoforskolin downregulated the transcription and expression of TNF-α and IL-6 induced by recombinant Borrelia burgdorferi basic membrane protein A (rBmpA). In a r at asthmatic model isoforskolin down-regulated production of transforming growth factor β1 (TGF-β1) and interleukin-1β (IL-1β) which was accompanied by inhibition of inflammation and airway remodeling.

6-ACETYL-7-DEACETYLFORSKOLIN Preparation Products And Raw materials

Raw materials

Preparation Products

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6-ACETYL-7-DEACETYLFORSKOLIN Suppliers

China 93 India 1 Switzerland 1 United Kingdom 1 United States 14 Global 110

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64657-21-2, 6-ACETYL-7-DEACETYLFORSKOLINRelated Search:

ISOMUCRONULATOL Isocurcumenol 2-TERTIARY PENTYL CYCLOHEXANYL ACETATE 4-TERT-AMYLCYCLOHEXANOL 4-METHOXY-4-METHYL-2-PENTANONE 4-tert-Butylcyclohexanol 1-(2,2,6-Trimethylcyclohexyl)- hexan-3-ol LIMETOL 2,2-DIMETHYLTETRAHYDROPYRAN-4-ONE Diacetone Alcohol 2,5-Dimethyl-2,5-hexanediol Pinacol O-TERT-BUTYLCYCLOHEXYL ACETATE KOHINOOL Isononyl acetate 2,2,4-Trimethyl-1,3-pentanediol Forskolin ACETIC ACID CIS-3,3,5-TRIMETHYLCYCLOHEXYL ESTER

6-ACETYL-7-DEACETYLFORSKOLIN

6BETA-ACETOXY-1ALPHA,7BETA,9ALPHA-TRIHYDROXY-8,13-EPOXY-LABD-14-EN-11-ONE

6BETA-ACETOXY-8,13-EPOXY-1ALPHA,7BETA,9ALPHA-TRIHYDROXY-LABD-14-EN-11-ONE

FORSKOLIN, 6-ACETYL-7-DEACETYL-

ISOFORSKOLIN

6-ACETYL-7-DEACETYLFORSKOLIN FROMCOLEUS FORSKOHLII

6β-acetoxy-1α,7β,9α-trihydroxy-8,13-epoxy-labd-14-en-11-one

Isoforskolin, 6β-Acetoxy-1α,7β,9α-trihydroxy-8,13-epoxy-labd-14-en-11-one

Coleol B

Coleonol B

(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-(Acetyloxy)-3-ethenyldodecahydro-5,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one

Isoforsklin

1H-Naphtho[2,1-b]pyran-1-one,6-(acetyloxy)-3-ethenyldodecahydro-5,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-,(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-

Isoforskolin（ Coleonol B,Excolabdone C）

Isoforskoli

(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5,10,10b-Trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyldodecahydro-1H-benzo[f]chromen-6-yl acetate

Isoforskolin-RM

64657-21-2

C22H34O7

AA to AL

Analytical Standards

Alphabetic

Analytical Chromatography Product Catalog

Diterpenoids

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract