Sodium thiomethoxide

Product Name: Sodium thiomethoxide
CAS No.: 5188-07-8
Chemical Name: Sodium thiomethoxide
Synonyms: SODIUM METHANETHIOLATE;SODIUM METHYL MERCAPTIDE;METHYL MERCAPTAN SODIUM SALT;Sodium thiomethylate;Sodium methylthiolate;SODIUM METHYLMERCAPTAN;SODIUM THIOMETHOXIDE, 21 VOL. % SOLN IN WATER, A PRODUCT OF ELF ATOCHEM (SMM);Sodium me;thioformate;methanethiolate
CBNumber: CB1476576
Molecular Formula: CH3NaS
Formula Weight: 70.09
MOL File: 5188-07-8.mol

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Sodium thiomethoxide Property

Density: 1.12[at 20℃]
vapor pressure: 29hPa at 25℃
Flash point:: 27°C
storage temp.: Air and moisture sensitive. Store under inert gas. Sensitive to carbon dioxide Exposure to moisture.
solubility: soluble in Water
form: Powder
color: White to off-white
Water Solubility: soluble
Merck: 14,5956
BRN: 3592983
InChI: InChI=1S/CH4S.Na/c1-2;/h2H,1H3;/q;+1/p-1
InChIKey: RMBAVIFYHOYIFM-UHFFFAOYSA-M
SMILES: CS[Na]
LogP: -2.33 at 20℃
CAS DataBase Reference: 5188-07-8(CAS DataBase Reference)
EPA Substance Registry System: Methanethiol, sodium salt (5188-07-8)

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Safety

Hazard Codes: C,F
Risk Statements: 31-34-20/21/22-11-35-25-10
Safety Statements: 26-36/37/39-45-16
RIDADR: UN 3263 8/PG 3
WGK Germany: 3
F: 1-34-10-13
HazardClass: 4.3
PackingGroup: II
HS Code: 29309090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 281018
Product name: Sodium thiomethoxide
Purity: 95%
Packaging: 1g
Price: $46.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: 281018
Product name: Sodium thiomethoxide
Purity: 95%
Packaging: 5g
Price: $125
Updated: 2024/03/01

TCI Chemical

Product number: M0096
Product name: Methyl Mercaptan Sodium Salt (ca. 15% in Water)
Packaging: 25g
Price: $38
Updated: 2024/03/01

TCI Chemical

Product number: M0096
Product name: Methyl Mercaptan Sodium Salt (ca. 15% in Water)
Packaging: 500g
Price: $144
Updated: 2024/03/01

Sigma-Aldrich

Product number: 71742
Product name: Sodium methanethiolate
Purity: technical, ≥90% (RT)
Packaging: 5g
Price: $122
Updated: 2024/03/01

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Sodium thiomethoxide Chemical Properties,Usage,Production

Description

Sodium methanethiolate or sodium thiomethoxide (CH3SNa, MeSNa) is the sodium conjugate base of methanethiol. This compound is commercially available as a white solid. Sodium Methanethiolate is used as a nucleophile in organic synthesis. This compound is also being used as a reagent to synthesize thiol-based suberoylanilide hydroxamic acid (SAHA) analogues, compounds that act as potent histone deacetylase inhibitors. It reacts with trifluoroacetic acid and water to produce the active form of sodium trifluoroacetate. The reaction mechanism is likely due to the formation of a bicyclic heterocycle that has been shown to be effective against a number of bacteria.

Chemical Properties

Very faint yellowish red clear liquid

Uses

Used to prepare a C-21 thioether of methyl 16-prednisolonecarboxylate by mesylate displacement.

Uses

Sodium thiomethoxide is a strong nucleophile used for the synthesis of methyl aryl sulfides from halo-arenes. Alkanethiolates are efficient reagents for SN2 dealkylation of esters and aryl ethers.

Reactivity Profile

Sodium thiomethoxide is a powerful nucleophile that can be used to prepare methylthioether and other organic compounds like ethyl bromide. Its hydrolysis in moist air produces methanethiol, which has a low odor threshold and a noxious fecal smell.

Purification Methods

Dissolve the salt (10g) in EtOH (10mL) and add Et2O (100mL). Cool and collect the precipitate, wash it with Et2O and dry it in a vacuum. It is a white powder which is very soluble in EtOH and H2O. [Billmann & Jensen Bull Soc Chim Fr 3 2318 1936, Beilstein 1 III 1212.]

Sodium thiomethoxide Preparation Products And Raw materials

Raw materials

Carbon disulfide Methanol Sodium hydroxide

Preparation Products

2-Aminoethylmethylsulfone hydrochloride Simetryne Prometryn 2-(METHYLTHIO)ETHANOL 2-(Methylthio)pyrazine 4,6-DICHLORO-2-(TRIFLUOROMETHYL)QUINOLINE 2-(METHYLTHIO)THIOPHENE Ametryn Methylthio acetaldoxime 5-(METHYLSULFONYL)THIOPHENE-2-CARBOXYLIC ACID ETHYL METHANESULFONYLACETATE 4-Methylthio-2-butanone Dimethyl sulfide METHYL MERCAPTAN Prairie Net Wettable Powder ALDICARB-OXIME 2-Methyl-3-(methylthio)pyrazine 5-(METHYLTHIO)THIOPHENE-2-CARBOXYLIC ACID ALDICARB 6-(METHYLTHIO)PYRIDINE-3-CARBOXYLIC ACID Methylthioethane

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Sodium thiomethoxide Suppliers

Americas 1 Australia 1 Belgium 1 Canada 1 China 293 Europe 1 Germany 2 India 12 Japan 1 Slovakia 1 Switzerland 1 United Kingdom 4 United States 18 Global 337

HBCChem, Inc.

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View Lastest Price from Sodium thiomethoxide manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: Sodium thiomethoxide 5188-07-8
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99.5%
Supply Ability: 100
Release date: 2024-11-06

Hebei Mojin Biotechnology Co., Ltd

Product: Sodium thiomethoxide 5188-07-8
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-09-22

Henan Aochuang Chemical Co.,Ltd.

Product: Sodium thiomethoxide 5188-07-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-17

5188-07-8, Sodium thiomethoxideRelated Search:

Sodium thiomethoxide solution

METHANETHIOL SODIUM SALT

METHYL MERCAPTAN SODIUM SALT

SODIUM METHANETHIOLATE

SODIUM METHYL MERCAPTIDE

SODIUM METHYL SULFIDE

SODIUM THIOMETHOXIDE

Sodium thiomethoxyde

SODIUM THIOMETHOXIDE, 21 VOL. % SOLN IN WATER, A PRODUCT OF ELF ATOCHEM (SMM)

1-Methanethiolsodiumsalt

Sodium methanethiol

Sodium methylthiolate

Sodium thiomethylate

Sodium thiomethoxide, pure, 95%

Sodium thiomethoxide, Methanethiol sodium salt

SODIUM METHYLMERCAPTAN

METHYL MERCAPTAN SODIUM SALT: 15% IN WATER

Methyl Mercaptan Sodium Salt (ca. 15% in Water)

Methanethiol sodium salt, Sodium methanethiolate, Sodium thiomethoxide

Sodium thiomethoxide, 95%, pure

Sodiothiomethane

Sodium Methanethiolate Solution

Sodium methanethiolate, 21% aq. soln.

Sodium methanethiolate ,95%

thioformate

Methanethiol, sodiuMsalt (1:1)

SodiuM Methanethiolate technical, >=90% (RT)

SodiuM thioMethoxide 95%

SodiuM thioMethoxide solution 21% in H2O

SodiuM thioMethoxide, 20% in water

Sodium Methanethiolate (~20% in Water)

sodiuM Methylsulfanide

SodiuM Methanethiolate, 15 wt.% solution in H2O

Sodium methanethiolate, 21% aqueous solution

Sodium me

Sodium methionine

Sodium thiomethoxide, 15% in water

methanethiolate

High purity Sodium thiomethoxide

5188-07-8

5188-7-8

1201108

1201-10-8

CH3NaS

CH3SNa

Building Blocks

Na (Sodium) Compounds (excluding simple sodium salts)

Typical Metal Compounds

Classes of Metal Compounds

Sulfur Compounds

Thiol/Mercaptan Salts

Organic Building Blocks

Classes of Metal Compounds

Na (Sodium) Compounds (excluding simple sodium salts)

Typical Metal Compounds

API

Aliphatics

Sulfur & Selenium Compounds