ChemicalBook > CAS DataBase List > TIQ-A

TIQ-A

Product Name
TIQ-A
CAS No.
420849-22-5
Chemical Name
TIQ-A
Synonyms
Thieno[2,3-c]isoquinolin-5(4H)-one;TIQ-A,poly ADP ribose polymerase,ADP-ribosyltransferase,TIQA,Inhibitor,PARP,TIQ A,inhibit,tankyrases,ADP-ribosylation,poly-ART
CBNumber
CB1504888
Molecular Formula
C11H7NOS
Formula Weight
201.24
MOL File
420849-22-5.mol
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TIQ-A Property

Melting point:
256-258°C
Boiling point:
282.2±9.0 °C(Predicted)
Density 
1.358±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: 16 mg/mL, soluble
form 
solid
pka
13.04±0.20(Predicted)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T2825
Product name
TIQ-A
Purity
≥98% (HPLC), solid
Packaging
1mg
Price
$109
Updated
2022/05/15
Sigma-Aldrich
Product number
T2825
Product name
TIQ-A
Purity
≥98% (HPLC), solid
Packaging
5mg
Price
$365
Updated
2022/05/15
Cayman Chemical
Product number
16112
Product name
TIQ-A
Purity
≥98%
Packaging
500μg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
16112
Product name
TIQ-A
Purity
≥98%
Packaging
1mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
16112
Product name
TIQ-A
Purity
≥98%
Packaging
5mg
Price
$230
Updated
2024/03/01
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TIQ-A Chemical Properties,Usage,Production

Chemical Properties

Dark Brown Solid

Uses

A cell permeable, potent PARP inhibitor with an IC50 of 450nM. Shown to be neuroprotective against oxygen-glucose deprivation injury in vitro in cultured murine cortical cells ( IC50 of 150nM) and in vivi in rat transient focal ischemia model (3 mg/kg ip).

TIQ-A Preparation Products And Raw materials

Raw materials

Preparation Products