ChemicalBook > CAS DataBase List > 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE

5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE

Product Name
5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE
CAS No.
63810-78-6
Chemical Name
5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE
Synonyms
5-Bromo-4-chloro-2-(methylthio)pyrimidine;5-Bromo-4-chloro-2-(methy...;Pyrimidine, 5-bromo-4-chloro-2-(methylthio)-;5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE;5-Bromo-4-chloro-2-(methylthio)pyrimidine >5-Bromo-4-chloro-2-(methylthio)pyrimidine ,97%;5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE ISO 9001：2015 REACH
CBNumber
CB1663121
Molecular Formula
C5H4BrClN2S
Formula Weight
239.52
MOL File
63810-78-6.mol
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5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE Property

Melting point:
45.0 to 49.0 °C
Boiling point:
309.5±22.0 °C(Predicted)
Density 
1.83±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
-1.97±0.29(Predicted)
color 
White to Almost white
InChI
InChI=1S/C5H4BrClN2S/c1-10-5-8-2-3(6)4(7)9-5/h2H,1H3
InChIKey
XVRYJQACDDVZEI-UHFFFAOYSA-N
SMILES
C1(SC)=NC=C(Br)C(Cl)=N1
CAS DataBase Reference
63810-78-6
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Safety

Risk Statements 
34-22
Safety Statements 
26-36/37/39-45
RIDADR 
2923
HazardClass 
8
PackingGroup 
Ⅲ
HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S445827
Product name
5-BROMO-4-CHLORO-2-METHYLTHIOPYRIMIDINE
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$30.7
Updated
2025/07/31
Sigma-Aldrich
Product number
S445827
Product name
5-BROMO-4-CHLORO-2-METHYLTHIOPYRIMIDINE
Purity
Aldrich
Packaging
50mg
Price
$29.8
Updated
2024/03/01
TCI Chemical
Product number
B4406
Product name
5-Bromo-4-chloro-2-(methylthio)pyrimidine
Purity
>98.0%(GC)
Packaging
1g
Price
$54
Updated
2025/07/31
TCI Chemical
Product number
B4406
Product name
5-Bromo-4-chloro-2-(methylthio)pyrimidine
Purity
min. 98.0 %
Packaging
5G
Price
$162
Updated
2025/07/31
TCI Chemical
Product number
B4406
Product name
5-Bromo-4-chloro-2-(methylthio)pyrimidine
Purity
min. 98.0 %
Packaging
5G
Price
$162
Updated
2025/07/31
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5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE Chemical Properties,Usage,Production

Chemical Properties

White solid

Synthesis

81560-03-4

63810-78-6

Step 3, Preparation of 5-bromo-4-chloro-2-methylthiopyrimidine: 5-bromo-2-(methylthio)pyrimidin-4(3H)-one (110 g) was dissolved in pyridine (400 g) and heated to 80°C. Phosphorus trichloride (100 g) was added dropwise with stirring. After the dropwise addition, the reaction temperature was maintained and stirring was continued for 5 hours. After completion of the reaction, the reaction mixture was cooled to room temperature and subsequently placed in an ice bath. The pH was adjusted to 8-9 with saturated sodium bicarbonate solution and then extracted with ethyl acetate (500 mL). The organic phase was dried with anhydrous magnesium sulfate, filtered and the filtrate was concentrated under reduced pressure to remove the solvent. The residue was recrystallized by a solvent mixture of petroleum ether and ethyl acetate (1:3, v/v) to give a pale yellow solid powder (98 g) in 83% yield.

References

[1] Patent: CN107488175, 2017, A. Location in patent: Paragraph 0008; 0010
[2] Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1982, vol. 36, # 1 B, p. 15 - 18

5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE Preparation Products And Raw materials

Raw materials

Phosphorus oxitrichloride 2-Thiouracil Bromine Acetic acid Iodomethane

Preparation Products

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5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE Suppliers

Americas 1 China 153 Europe 1 Germany 1 India 7 Japan 1 United Kingdom 4 United States 23 Global 191
TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23653
Advantage
75
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View Lastest Price from 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE 63810-78-6
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-11-13
Dideu Industries Group Limited
Product
5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE 63810-78-6
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-01
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE 63810-78-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11

63810-78-6, 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINERelated Search:

2,4-Diamino-6-hydroxypyrimidine 5-BROMO-4-CHLORO-2-METHANESULFONYL-PYRIMIDINE 5-BROMO-2-(METHYLTHIO)PYRIMIDINE 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE 4-Chloro-2-methylthiopyrimidine 5-Bromopyrimidine

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  • 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE ISO 9001：2015 REACH
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  • Heterocycle-Pyrimidine series