ChemicalBook > CAS DataBase List > N-Benzyloxycarbonyl-L-asparagine

N-Benzyloxycarbonyl-L-asparagine

Product Name
N-Benzyloxycarbonyl-L-asparagine
CAS No.
2304-96-3
Chemical Name
N-Benzyloxycarbonyl-L-asparagine
Synonyms
CBZ-L-ASPARAGINE;Z-ASN-OH;CBZ-L-ASN;CBZ-ASN-OH;CBZ-L-ASN-OH;Z-ASN;Z-L-ASN-OH;Z-Asn-OH 99%;Z-ASPARAGINE;CBZ asparagine
CBNumber
CB1677773
Molecular Formula
C12H14N2O5
Formula Weight
266.25
MOL File
2304-96-3.mol
More
Less

N-Benzyloxycarbonyl-L-asparagine Property

Melting point:
163-165 °C(lit.)
alpha 
6.5 º (c=2, CH3COOH)
Boiling point:
409.45°C (rough estimate)
Density 
1.2846 (rough estimate)
refractive index 
6.3 ° (C=1.6, AcOH)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
almost transparency in hot Methanol
form 
powder to crystal
pka
3.77±0.10(Predicted)
color 
White to Almost white
optical activity
[α]20/D +6°, c = 1.6 in acetic acid
BRN 
3085452
InChIKey
FUCKRCGERFLLHP-VIFPVBQESA-N
CAS DataBase Reference
2304-96-3(CAS DataBase Reference)
EPA Substance Registry System
L-Asparagine, N2-[(phenylmethoxy)carbonyl]- (2304-96-3)
More
Less

Safety

Hazard Codes 
Xi,Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
3
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
29242990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C6404
Product name
Z-Asn-OH
Purity
99%
Packaging
10g
Price
$108
Updated
2023/06/20
TCI Chemical
Product number
C0573
Product name
Nalpha-Carbobenzoxy-L-asparagine
Purity
>99.0%(T)
Packaging
1g
Price
$32
Updated
2025/07/31
TCI Chemical
Product number
C0573
Product name
Nalpha-Carbobenzoxy-L-asparagine
Purity
>99.0%(T)
Packaging
10g
Price
$77
Updated
2025/07/31
Usbiological
Product number
461082
Product name
Nα-Cbz-L-asparagine
Packaging
25g
Price
$403
Updated
2021/12/16
TRC
Product number
C227305
Product name
Nα-Cbz-L-asparagine
Packaging
250g
Price
$725
Updated
2021/12/16
More
Less

N-Benzyloxycarbonyl-L-asparagine Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

Nα-Cbz-L-asparagine is an N-Cbz-protected form of L-Asparagine (A790005). L-Asparagine was first isolated by Robiquet and Vauquelin from asparagus juice (a high source of L-asparagine). L-Asparagine is often incorporated into proteins, and is a basis for some cancer therapies as certain cancerous cells require L-asparagine for growth.

Synthesis

70-47-3

501-53-1

2304-96-3

At 0 °C, 6.05 g (45 mmol) of L-asparagine was dissolved in 100 mL of 10% Na2CO3 aqueous solution, followed by the addition of 56 mL of 1,4-dioxane and 6.9 mL (40 mmol) of benzyl chloroformate. The reaction mixture was stirred overnight at room temperature and poured into 300 mL of water. The aqueous phase was extracted three times with ether. The aqueous phase was acidified with 2N HCl aqueous solution until a white precipitate precipitated. The precipitate was collected by filtration and washed well with ether to give Cbz-L-asparagine (Compound 14) as an off-white solid (9 g, 84% yield); Mass Spectra (ESI): m/z = 267 [M + H]+, 289 [M + Na]+.

References

[1] Tetrahedron Asymmetry, 2015, vol. 26, # 21-22, p. 1273 - 1280
[2] Tetrahedron, 2000, vol. 56, # 16, p. 2513 - 2522
[3] Tetrahedron Letters, 2015, vol. 56, # 26, p. 3999 - 4001
[4] European Journal of Organic Chemistry, 2014, vol. 2014, # 31, p. 7015 - 7022
[5] Chemical Communications, 2016, vol. 52, # 60, p. 9438 - 9441

N-Benzyloxycarbonyl-L-asparagine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

N-Benzyloxycarbonyl-L-asparagine Suppliers

Americas 1 Belgium 2 China 318 Europe 3 France 2 Germany 6 Hungary 1 India 26 Japan 6 South Korea 1 Switzerland 6 United Kingdom 13 United States 59 Global 444
Shanghai Kaipu New Biotechnology Co. , Ltd.
Tel
17821452002; 17821452002
Email
info@shanghaikaipuxin.com
Country
China
ProdList
35
Advantage
58
Qufu Delu Biotechnology Co., Ltd
Tel
13562421518
Email
deluxe11@163.com
Country
China
ProdList
61
Advantage
58
Tianjin Chempharmatech Co.,Ltd.
Tel
022-66211079 13212288319
Fax
qq1405432731
Email
sales@chempharmatech.com
Country
China
ProdList
918
Advantage
55
AF Biochem Co., Ltd.
Tel
+86-028-60911900 13540204019
Email
sales@afbiochem.com
Country
China
ProdList
479
Advantage
57
SICHUAN TONGSHENG BIOPHARMACEUTICAL CO., LTD
Tel
0838-2809458 13350585791
Email
pharm@biots.cn
Country
China
ProdList
589
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9883
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11705
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 17550508557
Fax
QQ：3470079902
Email
675141927@qq.com
Country
China
ProdList
3199
Advantage
55
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
4000
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Nanjing Norris-Pharm Technology Co., Ltd
Tel
18652989687
Fax
+86-25-52131256
Email
sales@norris-pharm.com
Country
China
ProdList
8878
Advantage
55
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
150-2103-5486 18017383231
Fax
qq：2817624287
Email
983544897@qq.com
Country
China
ProdList
9342
Advantage
55
SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD.
Tel
21-33585366 13311639313
Fax
+86-21-34979012
Email
sales@shyrchem.com
Country
China
ProdList
806
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9546
Advantage
55
Bsisun HK Imoprt And Export Company Limited
Tel
+86-18068513926
Fax
0086-519-85153711
Country
China
ProdList
1277
Advantage
55
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Fax
86-0755-22642228
Email
cantotech@126.com
Country
China
ProdList
4566
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
15928766785 15928766785
Fax
QQ961458712
Email
wupengcheng@astatech.cn
Country
China
ProdList
1987
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7782
Advantage
58
Shanghai BeiZhuo Biotech Co., Ltd.
Tel
021-61119791,13386096464
Fax
021-50190009
Email
bzswkf@foxmail.com
Country
China
ProdList
3921
Advantage
50
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9874
Advantage
55
Ningbo Taikang Chemical Co., Ltd.
Tel
0574-87365517 18074210286
Fax
87367735
Email
sales@taikangchem.com
Country
China
ProdList
294
Advantage
58
Shanghai Meishui Chemical Technology Co., Ltd
Tel
021-60549325 18616193163
Fax
021-33250306
Country
China
ProdList
4526
Advantage
56
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9979
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7778
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9637
Advantage
58
More
Less

View Lastest Price from N-Benzyloxycarbonyl-L-asparagine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
N-Benzyloxycarbonyl-L-asparagine 2304-96-3
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
500kgs
Release date
2021-09-26
Hebei Chuanghai Biotechnology Co., Ltd
Product
N-Benzyloxycarbonyl-L-asparagine 2304-96-3
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-14
Henan Aochuang Chemical Co.,Ltd.
Product
N-Benzyloxycarbonyl-L-asparagine 2304-96-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-12

2304-96-3, N-Benzyloxycarbonyl-L-asparagineRelated Search:

Diethylstilbestrol Glycine CARBONYL SULFIDE Trimethoprim PYRAZOPHOS 1,1'-Carbonyldiimidazole D-(-)-Asparagine monohydrate L-Asparagine ASPARAGINASE tert-Butyl carbazate N-Carbobenzyloxyglycine 6-Aminocaproic acid FMOC-ASN(TRT)-OPFP Z-ASN-ONP Z-ASP-OME N-Cbz-L-Aspartic acid 4-tert-butyl ester Z-ASN(TRT)-OH Z-ARG(NO2)-OH

  • n2-[(phenylmethoxy)carbonyl]-l-asparagin
  • L-Asparagine, N-CBZ protected
  • N-α-Z-L-asparagine
  • N(a)-Benzyloxycarbonyl-L-asparagine
  • N-A-CBZ-L-ASPARAGINE CRYSTALLINE
  • N2-[(PHENYLMEHTOXY)CARBONYL]-L-ASPARAGINE
  • CBZ-L-Asparagine-OH
  • N(alpha)-Benzyloxycarbonyl-L-asparagine~Z-Asn-OH
  • N-Carbobenzyloxy-L-asparagine
  • N-CBZ-L-Asparagine N-Carbobenzyloxy-L-asparagine
  • n(à)-benzyloxycarbonyl-l-asparagine
  • n(à)-cbz-l-asparagine
  • Z-ASN
  • (S)-N-(BENZYLOXYCARBONYL)ASPARAGINE
  • 4-Amino-2-{[(benzyloxy)carbonyl]amino}-4-oxobutanoic acid
  • L-N-Cbz-Asparagine
  • N<sup>α</sup>-Carbobenzyloxy-L-asparagine
  • Z-L-AspaD23-RAgine
  • Nalpha-Carbobenzoxy-L-asparagine , 99.0%(T)
  • Z-Asn-OH 99%
  • 4-amino-4-oxo-2-[[oxo-(phenylmethoxy)methyl]amino]butanoic acid
  • Asparagine, N(2)-carboxy-, N(2)-benzyl ester, L-
  • Asparagine, N-(benzyloxy)carbonyl-
  • Carbobenzoxy-L-asparagin
  • Carbobenzoxy-L-asparagine
  • CBZ asparagine
  • Nα-Z-L-asparagine≥ 99% (HPLC)
  • N-CBZ-L-ASN-OH
  • Z-ASPARAGINE
  • Z-ASN-OH
  • Z-L-ASPARAGINE
  • Z-L-ASN-OH
  • N-CBZ-L-ASPARAGINE
  • N-CBZ-L-ASPARAGINE-OH
  • CBZ-ASN-OH
  • CBZ-L-ASN-OH
  • N(ɑ)-Benzyloxycarbonyl-L-asparagine, 98+%
  • N2-[(PHENYLMETHOXY)CARBONYL]-L-ASPARAGINE
  • N-ALPHA-BENZYLOXYCARBONYL-L-ASPARAGINE
  • N-BENZYLOXYCARBONYL-L-ASPARAGINE
  • N-CARBOBENZOXY-L-ASPARAGINE
  • N(ALPHA)-CBZ-L-ASPARAGINE
  • N-ALPHA-CARBOBENZYLOXY-L-ASPARAGINE
  • NALPHA-CARBOBENZOXY-L-ASPARAGINE
  • (S)-2-BENZYLOXYCARBONYLAMINO-SUCCINAMIC ACID
  • CBZ-L-ASN
  • CBZ-L-ASPARAGINE
  • CARBOBENZYLOXY-L-ASPARAGINE
  • BENZYLOXYCARBONYL-L-ASPARAGINE
  • N2-(Benzyloxycarbonyl)-L-asparagine
  • N2-[(Benzyloxy)carbonyl]-L-asparagine
  • N2-Benzyloxycarbonyl-L-asparagine
  • N(^a)-Benzyloxycarbonyl-L-asparagine, 98+%
  • Nalpha-Carbobenzyloxy-L-asparagine,98%
  • N(alpha)-Benzyloxycarbonyl-L-asparagine, 98+%
  • Z-L-ASPARGINE extrapure
  • (2S)-4-Amino-4-oxo-2-(phenylmethoxycarbonylamino)butanoic acid
  • L-Asparagine, N(2)-[(phenylmethoxy)carbonyl]-