ChemicalBook > CAS DataBase List > 4-Nitrobenzyl hydrogen malonate

4-Nitrobenzyl hydrogen malonate

Product Name
4-Nitrobenzyl hydrogen malonate
CAS No.
77359-11-6
Chemical Name
4-Nitrobenzyl hydrogen malonate
Synonyms
4-NITROBENZYLMALONATE;P-NITROBENZYLMALONATE;Mononitrobenzyl malonate;2-(4-Nitrobenzyl)malonate;MONO-4-NITROBENZYL MALONATE;MONO P-NITRO BENZYL MALONATE;4-Nitrobenzyl hydrogen malote;Mono-4-nitrobenzylMalonate>Mono-4-nitrobenzylmalonicacides;4-nitrobenzyl hydrogen malonate
CBNumber
CB1714632
Molecular Formula
C10H9NO6
Formula Weight
239.18
MOL File
77359-11-6.mol
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4-Nitrobenzyl hydrogen malonate Property

Melting point:
109 °C
Boiling point:
455.8±30.0 °C(Predicted)
Density 
1.447±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
2.49±0.32(Predicted)
color 
White to Almost white
InChIKey
RIGFMUNSTCPGNP-UHFFFAOYSA-N
CAS DataBase Reference
77359-11-6(CAS DataBase Reference)
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Safety

HS Code 
2917399590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
M1177
Product name
Mono-4-nitrobenzyl Malonate
Purity
>98.0%(T)
Packaging
5g
Price
$108
Updated
2024/03/01
TCI Chemical
Product number
M1177
Product name
Mono-4-nitrobenzyl Malonate
Purity
>98.0%(T)
Packaging
25g
Price
$276
Updated
2024/03/01
TRC
Product number
N495570
Product name
3-[(4-Nitrobenzyl)oxy]-3-oxopropanoicAcid
Packaging
1g
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
075703
Product name
3-((4-Nitrobenzyl)oxy)-3-oxopropanoic acid
Purity
95+%
Packaging
5g
Price
$13
Updated
2021/12/16
Matrix Scientific
Product number
075703
Product name
3-((4-Nitrobenzyl)oxy)-3-oxopropanoic acid
Purity
95+%
Packaging
10g
Price
$19
Updated
2021/12/16
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4-Nitrobenzyl hydrogen malonate Chemical Properties,Usage,Production

Uses

4-Nitrobenzyl hydrogen malonate is a reagent used in the synthesis of (±)-thienamycin, a β-Lactam antibiotics. Also, it is useful for chiral key intermediate of carbapenem syntheses.

Preparation

Preparation of mono-4-nitrobenzyl malonate:
In a flame-dried 150 mL pressure tube under argon, add 5.00 g (34.7 mmol) of Meldrum's acid and 40 mL of anhydrous MeCN.
Add 5.58 g (36.4 mmol) of p-nitrobenzyl alcohol to the resulting solution.
Cap the tube tightly and reflux the reaction overnight.
Concentrate the reaction mixture under reduced pressure.
Purify the residue using column chromatography with a 55/45 hexane/EtOAc mixture.
The resulting product is mono-4-nitrobenzyl malonate with a yield of 87%.

4-Nitrobenzyl hydrogen malonate Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Nitrobenzyl hydrogen malonate Suppliers

Xinxiang JuYuan Biological Technology Co., Ltd.
Tel
373-5071400 13937360405
Fax
86-373-5022250
Email
sales@xxkfqchem.com
Country
China
ProdList
15
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60
TaiZhou ZhiCheng Chemicals & Technology Co., LTD.
Tel
0523-82837785 13914525028
Fax
0523-87913272
Email
info@jszchg.com
Country
China
ProdList
249
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Shouguang Jiasheng Chemical Co., Ltd.
Tel
0536-7971999 18232719690
Fax
0536-7971999
Email
sgjiasheng@hotmail.com
Country
China
ProdList
353
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58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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81
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
Advantage
56
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
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Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
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XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8836
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52
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View Lastest Price from 4-Nitrobenzyl hydrogen malonate manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
Malonicacidmononitrobenzylester 77359-11-6
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-11-21
Hebei Yanxi Chemical Co., Ltd.
Product
4-Nitrobenzyl hydrogen malonate 77359-11-6
Price
US $0.00/kg
Min. Order
1kg
Purity
99.00%
Supply Ability
20tons
Release date
2023-09-15
Hebei Weibang Biotechnology Co., Ltd
Product
4-Nitrobenzyl hydrogen malonate 77359-11-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2024-10-24

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