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Hymexazol

Product Name
Hymexazol
CAS No.
10004-44-1
Chemical Name
Hymexazol
Synonyms
HYMEXAZOLE;5-METHYLISOXAZOL-3-OL;3-HYDROXY-5-METHYLISOXAZOLE;TACHIGALOZE;HYDROXYISOXAZOLE;5-Hydroxy-3-methylisoxazole;bucid;f-319;T 319;bucide
CBNumber
CB1754230
Molecular Formula
C4H5NO2
Formula Weight
99.09
MOL File
10004-44-1.mol
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Hymexazol Property

Melting point:
80°C
Boiling point:
185.54°C (rough estimate)
Density 
1.2992 (rough estimate)
vapor pressure 
0.182 Pa (25 °C)
refractive index 
1.4170 (estimate)
storage temp. 
2-8°C
solubility 
Soluble in alcohol, acetone, THF, chloroform
form 
Powder
pka
5.91 (weak acid)
Water Solubility 
65,100 mg l-1 (20 °C)
color 
White to Orange
Sensitive 
Light Sensitive
Merck 
14,4856
InChIKey
KGVPNLBXJKTABS-UHFFFAOYSA-N
CAS DataBase Reference
10004-44-1(CAS DataBase Reference)
EPA Substance Registry System
Hymexazol (10004-44-1)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-41-52/53
Safety Statements 
26-39-61
WGK Germany 
3
RTECS 
NY2932000
HS Code 
29349990
Toxicity
LD50 in male, female mice, rats (mg/kg): 2148, 1968, 4678, 3909 orally; 1297, 1167, 1924, 1884 s.c.; 445, 514, >1000, >1000 i.v.; in rats, rabbits (mg/kg): >10000, >2000 dermally (Nakamura, 1978)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H318Causes serious eye damage

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H3275
Product name
3-Hydroxy-5-methylisoxazole
Purity
≥90%
Packaging
50mg
Price
$131
Updated
2024/03/01
Sigma-Aldrich
Product number
H3275
Product name
3-Hydroxy-5-methylisoxazole
Purity
≥90%
Packaging
250mg
Price
$450
Updated
2024/03/01
TCI Chemical
Product number
H1348
Product name
3-Hydroxy-5-methylisoxazole
Purity
>98.0%(GC)
Packaging
5g
Price
$42
Updated
2024/03/01
TCI Chemical
Product number
H1348
Product name
3-Hydroxy-5-methylisoxazole
Purity
>98.0%(GC)
Packaging
25g
Price
$137
Updated
2024/03/01
Alfa Aesar
Product number
044450
Product name
3-Hydroxy-5-methylisoxazole, 97%
Packaging
5g
Price
$53.1
Updated
2024/03/01
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Hymexazol Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Pesticide.

Uses

Hymexazol is used to control soil-borne diseases caused by Fusarium, Aphanomyces, Pythium, Corficium and Typhula spp. in rice, sugar beet, fodder beet, vegetables, cucurbits, ornamentals, carnations and forest tree seedlings. It is also used as a seed dressing and stimulates some plant growth.

Uses

Agricultural fungicide and plant growth regulator.

Definition

ChEBI: A member of the class of isoxazoles carrying hydroxy and methyl substituents at positions 3 and 5 respectively. It is used worldwide as a systemic soil and seed fungicide for the control of diseases caused by Fusarium, Aphanomyces Pythium, and Corticium spp. in rice, sugarbeet, fodderbeet, vegetables, cucurbits, and ornamentals.

Synthesis Reference(s)

The Journal of Organic Chemistry, 48, p. 4307, 1983 DOI: 10.1021/jo00171a030

Metabolic pathway

Degradation of hymexazol in soil gave acetoacetamide and the product of rearrangement, 5-methyl-2(3H)-oxazolone.H owever, in plants the fungicide was principally converted into its O- and N-glucoside conjugates in the roots and shoots. The two main metabolites of hymexazol found in the urine of rats were the O-glucuronide and sulfate conjugates.

Degradation

Hymexazol is stable under alkaline conditions and relatively stable in acidic conditions. It is stable to sunlight and heat (PM). It should be noted that the parent molecule is tautomeric. Hymexazol is highly volatile and will be lost by volatilisation unless it is covered or incorporated into soil. The fungicide was completely biodegraded in natural water at 30 °C in 2 weeks and at 10-13 °C in 2 months (Rebenok and Kolesnikova, 1983). Hymexazol is stable in sunlight but it is readily degraded by ultraviolet light. Photolysis of an aqueous solution of the fungicide at 253.7 nm, using a low pressure Hg lamp, afforded the oxazolinone (2) as the major product and at least two unidentified minor components. The oxazolinone (2) has been found in soil studies as described below and is a product of rearrangement formed via an aziridinone intermediate as shown in Scheme 1 (Nakagawa et al., 1974).

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Hymexazol Suppliers

Jiangsu Rongshuo Pharmaceutical Co., Ltd
Tel
0000-15105138935 15105138935
Email
2622104407@qq.com
Country
China
ProdList
59
Advantage
58
Jiangsu Huirun Pharmaceutical Co., Ltd
Tel
15715295967
Email
3934839128@qq.com
Country
China
ProdList
143
Advantage
58
Henan Yanyuan Biotechnology Co., Ltd
Tel
18637186683
Email
2392060329@qq.com
Country
China
ProdList
31
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
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View Lastest Price from Hymexazol manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Hymexazol 10004-44-1
Price
US $0.00/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
10kg/month
Release date
2021-09-28
Hebei Weibang Biotechnology Co., Ltd
Product
Hymexazol 10004-44-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-19
Hebei Yanxi Chemical Co., Ltd.
Product
3-hydroxy-5-methylisoxazole 10004-44-1
Price
US $0.00/kg
Min. Order
1kg
Purity
98.00%
Supply Ability
20tons
Release date
2023-09-08

10004-44-1, HymexazolRelated Search:


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