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1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE

Product Name
1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE
CAS No.
6940-57-4
Chemical Name
1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE
Synonyms
2-Acyl-6-methylpyridine;2-ACETYL-6-METHYLPYRIDINE;6-Acetyl-2-methylpyridine;6-methyl-2-acetylpyridine;2-ACETYL-6-METHYL PYIDINE;2-Acetyl-6-Methylpyridine,98%;1-(6-Methyl-2-pyridinyl)ethanone;1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE;Ethanone, 1-(6-methyl-2-pyridinyl)-;1-(6-Methylpyridin-2-yl)ethan-1-one
CBNumber
CB1769607
Molecular Formula
C8H9NO
Formula Weight
135.16
MOL File
6940-57-4.mol
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1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE Property

Boiling point:
209℃
Density 
1.036±0.06 g/cm3(Predicted)
Flash point:
84°(183°F)
refractive index 
1.5150
storage temp. 
Inert atmosphere,Room Temperature
pka
3.24±0.10(Predicted)
form 
Solid
color 
Pale yellow
CAS DataBase Reference
6940-57-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
A3214
Product name
2-Acetyl-6-methylpyridine
Purity
>98.0%(GC)
Packaging
1g
Price
$75
Updated
2025/07/31
TCI Chemical
Product number
A3214
Product name
2-Acetyl-6-methylpyridine
Purity
>98.0%(GC)
Packaging
5g
Price
$186
Updated
2025/07/31
TRC
Product number
A189018
Product name
2-Acetyl-6-methylpyridine
Packaging
50mg
Price
$60
Updated
2021/12/16
Apolloscientific
Product number
OR13601
Product name
2-Acetyl-6-methylpyridine
Packaging
1g
Price
$27
Updated
2021/12/16
AK Scientific
Product number
Y9840
Product name
2-Acetyl-6-methylpyridine
Packaging
1g
Price
$27
Updated
2021/12/16
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1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE Chemical Properties,Usage,Production

Uses

2-Acetyl-6-methylpyridine is a flavor constituent of rum. A useful synthetic and industrial reagent.

Definition

ChEBI: 2-Acetyl-6-methylpyridine is an aromatic ketone.

Synthesis

71777-66-7

6940-57-4

The general procedure for the synthesis of 2-acetyl-6-methylpyridine from 1-(6-methylpyridin-2-yl)ethan-1-ol is as follows: to a solution of oxalyl chloride (20 mL, 225 mmol, 1.1 eq.) in dichloromethane (300 mL) was slowly added a solution of dimethyl sulfoxide (32 mL, 2.2 eq.) in dichloromethane (400 mL) at -75 °C for 1 hour. The resulting solution was stirred at -75 °C for 10 minutes, then a dichloromethane (600 mL) solution of 1-(6-methylpyridin-2-yl)ethan-1-ol (28 g, 204 mmol, 1 equiv) was slowly added. The reaction mixture was continued to be stirred at the same temperature for 10 minutes, followed by the slow addition of triethylamine (140 mL, 1.02 mol, 5 eq.). The reaction mixture was gradually warmed to 20 °C and stirred for 2 h, after which the reaction was quenched with water (500 mL). The organic phase was separated, dried over magnesium sulfate and concentrated in vacuum to give the crude product. Purification by silica gel column chromatography (eluent ratio 3:1 hexane/ethyl acetate) afforded 2-acetyl-6-methylpyridine (25.36 g, 92% yield).

References

[1] Patent: WO2004/26863, 2004, A1. Location in patent: Page 54

1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE Suppliers

Americas 1 Canada 1 China 133 Europe 1 Germany 2 India 6 Japan 1 United Kingdom 5 United States 25 USA 1 Global 176
AB Chemicals Inc.
Tel
--
Fax
--
Email
sales@abcheminc.com
Country
Canada
ProdList
1128
Advantage
47
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View Lastest Price from 1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE 6940-57-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-14
Shaanxi Dideu Medichem Co. Ltd
Product
3-Bromo-2-chloro-5-(trifluoromethyl)pyridine 71701-92-3
Price
US $0.10/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
1000 tons
Release date
2019-12-24
Shaanxi Dideu Medichem Co. Ltd
Product
2-Chloro-6-(trifluoromethyl)pyridine 39890-95-4
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2019-12-24

6940-57-4, 1-(6-METHYL-PYRIDIN-2-YL)-ETHANONERelated Search:

Pyrroloquinoline quinone N,N-DIMETHYLOXAMIC ACID 1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE 2,6-Diacetylpyridine Streptonigrin Pirenoxine 1-(2-Methylpyridin-3-yl)ethanone 5-ACETYL-2-METHYLPYRIDINE 1-(4-METHYL-PYRIDIN-2-YL)-ETHANONE 5-ACETYL-4-AMINO-6-METHYL-2-(METHYLTHIO)PYRIDINE-3-CARBONITRILE 2-(4-FLUOROPHENYL)-1-(6-METHYLPYRIDINE-2-YL)ETHANONE 1H-Indolo(3,2-c)quinoline-1,4(11H)-dione, 2-(1-aziridinyl)-6-methyl- 1-(3',4'-DIHYDROXYBENZOYL)-6,7-DIHYDROXYISOQUINOLINE-3-CARBOXYLIC ACID 1-(6-METHYL-3-NITROPYRIDIN-2-YL)ETHANONE 2-ACETYL-6-METHYL-ISONICOTINONITRILE 5,8-DIHYDRO-4,6-DIHYDROXY-5,8-DIOXO-2-QUINOLINECARBOXYLIC ACID Pyrroloquinoline quinone disodium salt 1-(3-AMINO-6-METHYLPYRIDIN-2-YL)ETHANONE

  • 1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE
  • 2-ACETYL-6-METHYLPYRIDINE
  • 1-(6-Methyl-2-pyridinyl)ethanone
  • 6-Acetyl-2-methylpyridine
  • 1-(6-Methylpyridin-2-yl)ethan-1-one
  • 2-ACETYL-6-METHYLPYRIDINE 1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE
  • Ethanone, 1-(6-methyl-2-pyridinyl)-
  • 6-methyl-2-acetylpyridine
  • 1-(6-Methylpyridin-2-yl)ethan-1-one, 6-Acetyl-2-picoline
  • 2-Acetyl-6-Methylpyridine,98%
  • 1-(6-Methyl-2-pyridin-2-yl)-ethanone
  • 1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE ISO 9001：2015 REACH
  • 2-Acetyl-6-methylpyridine 6940-57-4 1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE
  • 2-ACETYL-6-METHYL PYIDINE
  • 2-Acyl-6-methylpyridine
  • 1-(6-methylpyridine-2-yl)ethanone 98%
  • 6940-57-4
  • Pyridines
  • Pyridine series
  • Building Blocks
  • Pyridine