ChemicalBook > CAS DataBase List > 1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE

1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE

Product Name: 1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE
CAS No.: 6940-57-4
Chemical Name: 1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE
Synonyms: 2-Acyl-6-methylpyridine;2-ACETYL-6-METHYLPYRIDINE;6-Acetyl-2-methylpyridine;6-methyl-2-acetylpyridine;2-ACETYL-6-METHYL PYIDINE;2-Acetyl-6-Methylpyridine,98%;1-(6-Methyl-2-pyridinyl)ethanone;1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE;Ethanone, 1-(6-methyl-2-pyridinyl)-;1-(6-Methylpyridin-2-yl)ethan-1-one
CBNumber: CB1769607
Molecular Formula: C8H9NO
Formula Weight: 135.16
MOL File: 6940-57-4.mol

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1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE Property

Boiling point:: 209℃
Density: 1.036±0.06 g/cm3(Predicted)
Flash point:: 84°(183°F)
refractive index: 1.5150
storage temp.: Inert atmosphere,Room Temperature
pka: 3.24±0.10(Predicted)
form: Solid
color: Pale yellow
CAS DataBase Reference: 6940-57-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A3214
Product name: 2-Acetyl-6-methylpyridine
Purity: >98.0%(GC)
Packaging: 1g
Price: $75
Updated: 2025/07/31

TCI Chemical

Product number: A3214
Product name: 2-Acetyl-6-methylpyridine
Purity: >98.0%(GC)
Packaging: 5g
Price: $186
Updated: 2025/07/31

TRC

Product number: A189018
Product name: 2-Acetyl-6-methylpyridine
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Apolloscientific

Product number: OR13601
Product name: 2-Acetyl-6-methylpyridine
Packaging: 1g
Price: $27
Updated: 2021/12/16

AK Scientific

Product number: Y9840
Product name: 2-Acetyl-6-methylpyridine
Packaging: 1g
Price: $27
Updated: 2021/12/16

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1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE Chemical Properties,Usage,Production

Uses

2-Acetyl-6-methylpyridine is a flavor constituent of rum. A useful synthetic and industrial reagent.

Definition

ChEBI: 2-Acetyl-6-methylpyridine is an aromatic ketone.

Synthesis

71777-66-7

6940-57-4

The general procedure for the synthesis of 2-acetyl-6-methylpyridine from 1-(6-methylpyridin-2-yl)ethan-1-ol is as follows: to a solution of oxalyl chloride (20 mL, 225 mmol, 1.1 eq.) in dichloromethane (300 mL) was slowly added a solution of dimethyl sulfoxide (32 mL, 2.2 eq.) in dichloromethane (400 mL) at -75 °C for 1 hour. The resulting solution was stirred at -75 °C for 10 minutes, then a dichloromethane (600 mL) solution of 1-(6-methylpyridin-2-yl)ethan-1-ol (28 g, 204 mmol, 1 equiv) was slowly added. The reaction mixture was continued to be stirred at the same temperature for 10 minutes, followed by the slow addition of triethylamine (140 mL, 1.02 mol, 5 eq.). The reaction mixture was gradually warmed to 20 °C and stirred for 2 h, after which the reaction was quenched with water (500 mL). The organic phase was separated, dried over magnesium sulfate and concentrated in vacuum to give the crude product. Purification by silica gel column chromatography (eluent ratio 3:1 hexane/ethyl acetate) afforded 2-acetyl-6-methylpyridine (25.36 g, 92% yield).

References

[1] Patent: WO2004/26863, 2004, A1. Location in patent: Page 54

1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE 6940-57-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-14

Shaanxi Dideu Medichem Co. Ltd

Product: 3-Bromo-2-chloro-5-(trifluoromethyl)pyridine 71701-92-3
Price: US $0.10/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 1000 tons
Release date: 2019-12-24

Shaanxi Dideu Medichem Co. Ltd

Product: 2-Chloro-6-(trifluoromethyl)pyridine 39890-95-4
Price: US $0.10/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000 tons
Release date: 2019-12-24

6940-57-4, 1-(6-METHYL-PYRIDIN-2-YL)-ETHANONERelated Search:

Pyrroloquinoline quinone N,N-DIMETHYLOXAMIC ACID 1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE 2,6-Diacetylpyridine Streptonigrin Pirenoxine 1-(2-Methylpyridin-3-yl)ethanone 5-ACETYL-2-METHYLPYRIDINE 1-(4-METHYL-PYRIDIN-2-YL)-ETHANONE 5-ACETYL-4-AMINO-6-METHYL-2-(METHYLTHIO)PYRIDINE-3-CARBONITRILE 2-(4-FLUOROPHENYL)-1-(6-METHYLPYRIDINE-2-YL)ETHANONE 1H-Indolo(3,2-c)quinoline-1,4(11H)-dione, 2-(1-aziridinyl)-6-methyl- 1-(3',4'-DIHYDROXYBENZOYL)-6,7-DIHYDROXYISOQUINOLINE-3-CARBOXYLIC ACID 1-(6-METHYL-3-NITROPYRIDIN-2-YL)ETHANONE 2-ACETYL-6-METHYL-ISONICOTINONITRILE 5,8-DIHYDRO-4,6-DIHYDROXY-5,8-DIOXO-2-QUINOLINECARBOXYLIC ACID Pyrroloquinoline quinone disodium salt 1-(3-AMINO-6-METHYLPYRIDIN-2-YL)ETHANONE

1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE

2-ACETYL-6-METHYLPYRIDINE

1-(6-Methyl-2-pyridinyl)ethanone

6-Acetyl-2-methylpyridine

1-(6-Methylpyridin-2-yl)ethan-1-one

2-ACETYL-6-METHYLPYRIDINE 1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE

Ethanone, 1-(6-methyl-2-pyridinyl)-

6-methyl-2-acetylpyridine

1-(6-Methylpyridin-2-yl)ethan-1-one, 6-Acetyl-2-picoline

2-Acetyl-6-Methylpyridine,98%

1-(6-Methyl-2-pyridin-2-yl)-ethanone

1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE ISO 9001：2015 REACH

2-Acetyl-6-methylpyridine 6940-57-4 1-(6-METHYL-PYRIDIN-2-YL)-ETHANONE

2-ACETYL-6-METHYL PYIDINE

2-Acyl-6-methylpyridine

1-(6-methylpyridine-2-yl)ethanone 98%

6940-57-4

Pyridines

Pyridine series

Building Blocks

Pyridine