5-Bromo-2-nitropyridine

Product Name: 5-Bromo-2-nitropyridine
CAS No.: 39856-50-3
Chemical Name: 5-Bromo-2-nitropyridine
Synonyms: 2-NITRO-5-BROMOPYRIDINE;AKOS BBS-00001330;5-Bromo-2-nitropyrid;3-BROMO-6-NITROPYRIDINE;5-BROMO-2-NITROPYRIDINE;5-Bromo-2-notropyridine;2-Nitro-5-borMopyridine;Palbociclib impurity A;Pyridine, 5-broMo-2-nitro-;5-Bromo-2-nitropyridine 99%
CBNumber: CB1773370
Molecular Formula: C5H3BrN2O2
Formula Weight: 202.99
MOL File: 39856-50-3.mol

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5-Bromo-2-nitropyridine Property

Melting point:: 148-150 °C (lit.)
Boiling point:: 292.3±20.0 °C(Predicted)
Density: 1.833±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: -4.95±0.22(Predicted)
color: White to yellow to beige powder or crystal or chunks
BRN: 120878
InChI: InChI=1S/C5H3BrN2O2/c6-4-1-2-5(7-3-4)8(9)10/h1-3H
InChIKey: ATXXLNCPVSUCNK-UHFFFAOYSA-N
SMILES: C1([N+]([O-])=O)=NC=C(Br)C=C1
CAS DataBase Reference: 39856-50-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36/37
WGK Germany: 3
HazardClass: IRRITANT
PackingGroup: III
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 520411
Product name: 5-Bromo-2-nitropyridine
Purity: 99%
Packaging: 5g
Price: $23.76
Updated: 2024/03/01

TCI Chemical

Product number: B2766
Product name: 5-Bromo-2-nitropyridine
Purity: >98.0%(GC)
Packaging: 1g
Price: $20
Updated: 2024/03/01

TCI Chemical

Product number: B2766
Product name: 5-Bromo-2-nitropyridine
Purity: >98.0%(GC)
Packaging: 5g
Price: $57
Updated: 2024/03/01

Alfa Aesar

Product number: L19748
Product name: 5-Bromo-2-nitropyridine, 98+%
Packaging: 5g
Price: $90.65
Updated: 2024/03/01

Alfa Aesar

Product number: L19748
Product name: 5-Bromo-2-nitropyridine, 98+%
Packaging: 1g
Price: $30.6
Updated: 2021/12/16

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5-Bromo-2-nitropyridine Chemical Properties,Usage,Production

Chemical Properties

Colorless solid

Uses

5-Bromo-2-nitropyridine is employed as a reagent in the synthesis of novel benzinidazoles, potent inhibitors of TIE-2 and VEGFR-2 Tyrosine (T899975) kinase receptors.

Preparation

5-Bromo-2-nitropyridine was prepared from the corresponding amine via hydrogen peroxide oxidation in large scale production. N-Bromosuccinimide (NBS) bromination of 2-aminopyridine in acetonitrile at 0-5 °C delivered 5-bromo-2- aminopyridine with good regioselectivity (>20:1). The brominated amino-pyridine was then reacted with the oxidant mixture, yielding 5-Bromo-2-nitropyridine after dilution with water and isopropanol[1].

Synthesis Reference(s)

[1] Agosti, Alessandro, et al. "Handling Hydrogen Peroxide Oxidations on a Large Scale: Synthesis of 5-Bromo-2-nitropyridine." Organic Process Research & Development 21.3(2017):451-459.

5-Bromo-2-nitropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Bromo-2-nitropyridine Suppliers

Americas 1 Austria 1 China 430 Europe 3 France 2 Germany 6 Hungary 2 India 86 Ireland 1 Japan 4 Jordan 1 Switzerland 4 The Netherlands 1 Ukraine 2 United Kingdom 15 United States 59 Global 618

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

TCI Japan

Tel: --
Fax: --
Email: @TCIchemicals.com
Country: Japan
ProdList: 2741
Advantage: 58

FUJIFILM Wako Pure Chemical Corporation

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Email: ffwk-cservice@fujifilm.com
Country: Japan
ProdList: 6222
Advantage: 58

Wako Pure Chemical Industries, Ltd.

Tel: --
Fax: --
Email: labchem-tec@wako-chem.co.jp
Country: Japan
ProdList: 6819
Advantage: 80

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View Lastest Price from 5-Bromo-2-nitropyridine manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 5-Bromo-2-nitropyridine 39856-50-3
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-11-19

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 5-Bromo-2-nitropyridine 39856-50-3
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-01-30

hebei hongtan Biotechnology Co., Ltd

Product: 5-Bromo-2-nitropyridine 39856-50-3
Price: US $30.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000kg
Release date: 2024-05-14

39856-50-3, 5-Bromo-2-nitropyridineRelated Search:

5-Bromo-2-pyridinecarbonitrile 5-Chloro-2-bromo-3-nitropyridine 5-Bromo-2-nitropyridine 3-BROMO-5-NITROPYRIDINE,2-BROMO-5-NITROPYRIDINE ,98% 3-BROMO-2-HYDRAZINO-5-NITROPYRIDINE 3,5-DIBROMO-4-NITROPYRIDINE 2-CHLORO-3-BROMO-5-NITROPYRIDINE 4-AMINO-3-BROMO-5-NITROPYRIDINE 2,6-Dibromo-3-nitropyridine 4-BROMO-3-NITROPYRIDINE 3,5-DIBROMO-2-NITROPYRIDINE 3-AMINO-5-BROMO-2-NITROPYRIDINE 2-BROMO-4-NITROPYRIDINE N-OXIDE,2-BROMO-4-NITROPYRIDINE 1-OXIDE,2-BROMO-4-NITROPYRIDINE1N-OXIDE 3-BROMO-4-NITROPYRIDINE,3-BROMO-4-NITROPYRIDINE 97% 2-BROMO-4-NITROPYRIDINE 2-Methoxy-3-Bromo-5-Nitropyridine 2-Amino-3-bromo-5-nitropyridine 98%,2-AMINO-3-BROMO-5-NITROPYRIDINE 2,3-DIBROMO-5-NITRO PYRIDINE

AKOS BBS-00001330

2-NITRO-5-BROMOPYRIDINE

5-BROMO-2-NITROPYRIDINE

3-BROMO-6-NITROPYRIDINE

2-NITRO-5-BROMO PYRIDINE(5-BROMO-2-NITROPYRIDINE)

5-BROMO-2-NITROPYRIDINE, 98+%

3-Bromo-6-nitropyridine (5-Bromo-2-nitropyridine)

5-Bromo-2-notropyridine

5-Bromo-2-nitropyrid

5-BroMo-2-nitropyridine, 99% 1GR

Pyridine, 5-broMo-2-nitro-

2-Nitro-5-borMopyridine

2-Nitro-5-broMopyridine, 98%, 98%

2 - nitro - 5 - broMide pyridine

Palbociclib impurity A

5-Bromo-2-nitropyridine 99%

5-Bromo-2-nitropyridine &gt

5-Bromo-2-nitropyridine ISO 9001：2015 REACH

39856-50-3 5-Bromo-2-nitropyridine

5-BROMO-2-NITROPYRIDINE Extra Pure

39856-50-3

39586-50-3

2-NITRO-5-BROMO

851607-56-6

C5H3N2O2Br

Pyridines

Heterocyclic Building Blocks

Halogenated Heterocycles

Bromopyridines

Halopyridines

Building Blocks

Heterocycle-Pyridine series

blocks

Bromides

Pyridines

Pyridine

Pyridines, Pyrimidines, Purines and Pteredines

Organohalides

Bromopyridines

Halopyridines

C5Heterocyclic Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Pyridines derivates

39856-50-3