2-Amino-3-bromo-5-nitropyridine
- Product Name
- 2-Amino-3-bromo-5-nitropyridine
- CAS No.
- 15862-31-4
- Chemical Name
- 2-Amino-3-bromo-5-nitropyridine
- Synonyms
- AURORA KA-367;3-BROMO-5-NITROPYRIDIN-2-AMINE;2-AMINO-3-BROMO-5-NITROPYRIDINE;2-PYRIDINAMINE, 3-BROMO-5-NITRO-;3-Bromo-5-nitro-pyridin-2-ylamine;2-Amino-3-bromo-5-nitropyridine 98%;2-Amino-3-bromo-5-nitropyridine,98%;2-AMino-3-broMo-5-nitropyridine, 98% 1GR;2-Amino-3-bromo-5-nitropyridine ISO 9001：2015 REACH
- CBNumber
- CB6735261
- Molecular Formula
- C5H4BrN3O2
- Formula Weight
- 218.01
- MOL File
- 15862-31-4.mol
2-Amino-3-bromo-5-nitropyridine Property
- Melting point:
- 215-219 °C
- Boiling point:
- 347.3±37.0 °C(Predicted)
- Density
- 1.9128 (rough estimate)
- refractive index
- 1.6200 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 0.06±0.49(Predicted)
- form
- Powder
- color
- Beige to orange-brown
- InChI
- InChI=1S/C5H4BrN3O2/c6-4-1-3(9(10)11)2-8-5(4)7/h1-2H,(H2,7,8)
- InChIKey
- OFXNHXMPRZDIDM-UHFFFAOYSA-N
- SMILES
- C1(N)=NC=C([N+]([O-])=O)C=C1Br
- CAS DataBase Reference
- 15862-31-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 37/39-26-36
- HazardClass
- IRRITANT
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- A602470
- Product name
- 2-Amino-3-bromo-5-nitropyridine
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FA36852
- Product name
- 2-Amino-3-bromo-5-nitropyridine
- Packaging
- 25g
- Price
- $65
- Updated
- 2021/12/16
- Product number
- CS-W002708
- Product name
- 2-Amino-3-bromo-5-nitropyridine
- Purity
- 97.69%
- Packaging
- 100g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- JK411945
- Product name
- 2-Amino-3-bromo-5-nitropyridine
- Purity
- 98%
- Packaging
- 5g
- Price
- $42
- Updated
- 2021/12/16
- Product number
- 024635
- Product name
- 2-Amino-3-bromo-5-nitropyridine
- Purity
- 98%
- Packaging
- 25g
- Price
- $49
- Updated
- 2021/12/16
2-Amino-3-bromo-5-nitropyridine Chemical Properties,Usage,Production
Chemical Properties
Beige to orange-brown powder
Uses
2-Amino-3-bromo-5-nitropyridine is a useful intermediate for organic synthesis.
Synthesis
4214-76-0
15862-31-4
Step a: Bromine (38 g, 0.24 mol) was slowly added dropwise to a solution of 2-amino-5-nitropyridine (30 g, 0.22 mol) in acetic acid (200 mL) at 10 °C. After the dropwise addition was completed, the reaction mixture was warmed to 20 °C and stirring was continued for 30 min. Upon completion of the reaction, the solid product was collected by filtration and dissolved in ethyl acetate (200 mL). The pH of the mixture was adjusted to 8-9 with saturated aqueous sodium bicarbonate. the organic layer was separated and the aqueous layer was extracted with ethyl acetate (100 mL x 3). The organic layers were combined, washed sequentially with water and brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to give 2-amino-3-bromo-5-nitropyridine (14.8 g, 32% yield). The product was characterized by 1H-NMR (CDCl3,400MHz): δ 8.94 (d, J=2.4Hz, 1H), 8.50 (d, J=2.4Hz, 1H), 5.67 (brs, 2H).
References
[1] Patent: US2009/253736, 2009, A1. Location in patent: Page/Page column 25
[2] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 14, p. 3853 - 3860
[3] Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1920, vol. 50, p. 494
[4] Chem. Zentralbl., 1923, vol. 94, # III, p. 1021
[5] Zhurnal Obshchei Khimii, 1940, vol. 10, p. 1827,1836
2-Amino-3-bromo-5-nitropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Amino-3-bromo-5-nitropyridine manufacturers
- Product
- 2-Amino-3-bromo-5-nitropyridine 15862-31-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-29
- Product
- 2-Amino-3-bromo-5-nitropyridine 15862-31-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-17
- Product
- 3-Bromo-5-nitropyridin-2-amine 15862-31-4
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-30