4-BROMO-1-NAPHTALENECARBOXYLIC ACID

Product Name: 4-BROMO-1-NAPHTALENECARBOXYLIC ACID
CAS No.: 16650-55-8
Chemical Name: 4-BROMO-1-NAPHTALENECARBOXYLIC ACID
Synonyms: 4-BROMO-1-NAPHTHOIC ACID;4-Bromo-1-naphthalenecarboxylic acid;4-Bromo-1-naphthoic;afoxolaner Impurity 20;4-Bromo-1-naphthoic acid 98%;4-Bromo-1-naphthoic acid 97+%;4-BROMO-1-NAPHTALENECARBOXYLIC ACID;4-BROMONAPHTHALENE-1-CARBOXYLIC ACID;4-Bromo-naphthalen-1-carboxylic acid;1-Naphthalenecarboxylicacid, 4-bromo-
CBNumber: CB1807174
Molecular Formula: C11H7BrO2
Formula Weight: 251.08
MOL File: 16650-55-8.mol

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4-BROMO-1-NAPHTALENECARBOXYLIC ACID Property

Melting point:: 198-200
Boiling point:: 408.8±28.0 °C(Predicted)
Density: 1.648±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: Solid
pka: 3.48±0.10(Predicted)
color: White to Light yellow
Water Solubility: Slightly soluble in water.
InChI: InChI=1S/C11H7BrO2/c12-10-6-5-9(11(13)14)7-3-1-2-4-8(7)10/h1-6H,(H,13,14)
InChIKey: FIJIPZQZVLCOMB-UHFFFAOYSA-N
SMILES: C1(C(O)=O)=C2C(C=CC=C2)=C(Br)C=C1
CAS DataBase Reference: 16650-55-8

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Safety

Hazard Codes: Xi,N,Xn
Risk Statements: 22-36-50/53
Safety Statements: 26-60-61
Hazard Note: Harmful/Irritant/Keep Cold
HS Code: 2916399090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B4949
Product name: 4-Bromo-1-naphthoic Acid
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $38
Updated: 2025/07/31

TCI Chemical

Product number: B4949
Product name: 4-Bromo-1-naphthoic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $107
Updated: 2025/07/31

TRC

Product number: B697935
Product name: 4-Bromo-1-naphthoic Acid
Packaging: 1g
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB143045
Product name: 4-Bromo-1-naphthoic acid
Packaging: 1g
Price: $89
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB143045
Product name: 4-Bromo-1-naphthoic acid
Packaging: 500mg
Price: $50
Updated: 2021/12/16

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4-BROMO-1-NAPHTALENECARBOXYLIC ACID Chemical Properties,Usage,Production

Uses

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.

Synthesis

56052-26-7

16650-55-8

General procedure for the synthesis of 4-bromo-1-naphthalenecarboxylic acid from (4-bromonaphthalen-1-yl)methanol: A mixture of chromic anhydride (1.81 g, 18.1 mmol) and concentrated hydrochloric acid was added slowly and dropwise to a solution of (4-bromo-1-naphthalenyl)methanol (1.329 g, 6.027 mmol) in acetone (50 mL). A dilute sulfuric acid solution prepared by dissolving sulfuric acid (2 mL) in water (9 mL) was added dropwise to the reaction system under cooling conditions in an ice bath. After the dropwise addition, the reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the acetone was removed by distillation under reduced pressure. The residue was dissolved in ethyl acetate, washed three times sequentially with water and dried with anhydrous magnesium sulfate. The organic solvent was removed by concentration under reduced pressure, and the resulting crude product was recrystallized with a solvent mixture of ethanol-water to give the target product 4-bromo-1-naphthalenecarboxylic acid. The product was a light brown crystal with a yield of 1.272 g, 84% yield, melting point 223-224 °C. 1H-NMR (CDCl3-DMSO-d6, 200 MHz) δ 7.60-7.69 (2H, m), 7.83 (1H, d, J = 7.8 Hz), 8.06 (1H, d, J = 8.2 Hz), 8.28-8.36 (1H , m), 8.99-9.08 (1H, m).IR (KBr, cm-1) 3100-2500, 1694, 1566, 1508, 1279, 1252, 1190, 903, 785, 762.Elemental analysis (C11H7BrO2) Calculated values: C, 52.62; H, 2.81.Measured values: C, 52.42; H, 2.87. H, 2.87.

References

[1] Patent: EP1362846, 2003, A1. Location in patent: Page/Page column 55-56

4-BROMO-1-NAPHTALENECARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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4-BROMO-1-NAPHTALENECARBOXYLIC ACID Suppliers

Americas 1 Canada 1 China 127 Europe 1 Germany 1 India 5 Japan 1 Switzerland 1 United Kingdom 5 United States 13 Global 156

Hefei Yule Pharmaceutical Technology Co., Ltd

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View Lastest Price from 4-BROMO-1-NAPHTALENECARBOXYLIC ACID manufacturers

Jiangsu Magic Biotechnology Co., Ltd

Product: 4-BROMO-1-NAPHTALENECARBOXYLIC ACID 16650-55-8
Price: US $0.00-0.00/kg
Min. Order: 25kg
Purity: 99%
Supply Ability: 20tons
Release date: 2023-05-04

Career Henan Chemical Co

Product: 4-BROMO-1-NAPHTALENECARBOXYLIC ACID 16650-55-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg,5kg,100kg
Release date: 2019-07-04

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4-BROMONAPHTHALENE-1-CARBOXYLIC ACID

4-BROMO-1-NAPHTALENECARBOXYLIC ACID

4-BROMO-1-NAPHTHOIC ACID

4-Bromo-1-naphthoic acid 98%

4-Bromo-1-naphthalenecarboxylic acid

4-Bromo-1-naphthoic acid 97+%

4-Bromonaphthalene-1-carboxylic acid, 1-Bromo-4-carboxynaphthalene

1-Naphthalenecarboxylicacid, 4-bromo-

1-Naphthalenecarboxylicacid, 4-bromo-, methyl ester

4-Bromo-1-Naphthalene-1-Carboxylic acid

4-Bromo-1-naphthoic

afoxolaner Impurity 20

4-Bromo-naphthalen-1-carboxylic acid

16650-55-8

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