4-CYANOQUINOLINE
- Product Name
- 4-CYANOQUINOLINE
- CAS No.
- 2973-27-5
- Chemical Name
- 4-CYANOQUINOLINE
- Synonyms
- 4-CYANOQUINOLINE;cinchoninonitrile;4-Quinolinecarbonitrile;QUINOLINE-4-CARBONITRILE
- CBNumber
- CB1841033
- Molecular Formula
- C10H6N2
- Formula Weight
- 154.17
- MOL File
- 2973-27-5.mol
4-CYANOQUINOLINE Property
- Melting point:
- 103.5°C
- Boiling point:
- 267.53°C (rough estimate)
- Density
- 1.1975 (rough estimate)
- refractive index
- 1.4820 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 1.55±0.13(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2933499090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- Y5377
- Product name
- Quinoline-4-carbonitrile
- Packaging
- 100mg
- Price
- $104
- Updated
- 2021/12/16
- Product number
- OR959787
- Product name
- 4-cyanoquinoline
- Purity
- 97%
- Packaging
- 250mg
- Price
- $305
- Updated
- 2021/12/16
- Product number
- 3H37-1-8K
- Product name
- 4-Cyanoquinoline
- Purity
- 97%
- Packaging
- 250mg
- Price
- $336
- Updated
- 2021/12/16
- Product number
- OR959787
- Product name
- 4-cyanoquinoline
- Purity
- 97%
- Packaging
- 1g
- Price
- $754
- Updated
- 2021/12/16
- Product number
- 187749
- Product name
- Quinoline-4-carbonitrile
- Packaging
- 5g
- Price
- $810
- Updated
- 2021/12/16
4-CYANOQUINOLINE Chemical Properties,Usage,Production
Synthesis
4363-93-3
2973-27-5
General procedure for the synthesis of quinoline-4-carbonitrile from 4-quinolinecarboxaldehyde: 4-quinolinecarboxaldehyde (54 mg, 0.5 mmol) and ammonium acetate (385 mg, 5.0 mmol) were dissolved in acetonitrile (6 mL) at room temperature, followed by the addition of trimethylphenyltrimethylammonium (376 mg, 1.0 mmol). The reaction mixture was stirred continuously for 21 hours at room temperature. Upon completion of the reaction, the reaction mixture was sequentially treated with 0.5 M Na2S2O3 aqueous solution (10 mL) and 1.0 M NaHCO3 aqueous solution (15 mL) and then extracted with ethyl acetate (60 mL). The organic phase was washed sequentially with 0.5 M Na2S2O3 aqueous solution and saturated NaCl aqueous solution and finally dried with anhydrous MgSO4.
References
[1] Heterocycles, 2016, vol. 92, # 10, p. 1796 - 1802
[2] Patent: EP1555257, 2005, A1. Location in patent: Page/Page column 24
4-CYANOQUINOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
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