methyl quinoline-3-carboxylate

Product Name: methyl quinoline-3-carboxylate
CAS No.: 53951-84-1
Chemical Name: methyl quinoline-3-carboxylate
Synonyms: Methyl 3-quinolinecarboxylate;methyl quinoline-3-carboxylate;Methyl-Quinolone-3-Carboxylate;Quinoline-3-carboxylic acid methyl ester;3-Quinolinecarboxylic acid, methyl ester
CBNumber: CB91454274
Molecular Formula: C11H9NO2
Formula Weight: 187.19
MOL File: 53951-84-1.mol

More

Less

methyl quinoline-3-carboxylate Property

Melting point:: 73-74 °C
Boiling point:: 294.5±13.0 °C(Predicted)
Density: 1.210±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 3.11±0.11(Predicted)
Appearance: Off-white to light yellow Solid

More

Less

Safety

HS Code: 2933499090

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

TRC

Product number: M327223
Product name: MethylQuinoline-3-carboxylate
Packaging: 500mg
Price: $155
Updated: 2021/12/16

Matrix Scientific

Product number: 083546
Product name: Methyl quinoline-3-carboxylate
Purity: 95%
Packaging: 1g
Price: $414
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0303200
Product name: METHYL QUINOLINE-3-CARBOXYLATE
Purity: 95.00%
Packaging: 5MG
Price: $502.06
Updated: 2021/12/16

AK Scientific

Product number: Z4848
Product name: Methylquinoline-3-carboxylate
Packaging: 10g
Price: $691
Updated: 2021/12/16

AK Scientific

Product number: Z4848
Product name: Methylquinoline-3-carboxylate
Packaging: 25g
Price: $1211
Updated: 2021/12/16

More

Less

methyl quinoline-3-carboxylate Chemical Properties,Usage,Production

Synthesis Reference(s)

Journal of Medicinal Chemistry, 25, p. 1081, 1982 DOI: 10.1021/jm00351a015

Synthesis

67-56-1

6480-68-8

53951-84-1

General procedure for the synthesis of methyl 3-quinolinecarboxylate from methanol and quinoline-3-carboxylic acid: quinoline-3-carboxylic acid (3 g, 17.32 mmol) was dissolved in methanol (30 mL) and cooled at 0°C in an ice bath. Subsequently, thionyl chloride (1.264 mL, 17.32 mmol) was added slowly and dropwise, then the reaction mixture was heated to 80°C and kept overnight. The reaction progress was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the methanol was evaporated under reduced pressure and the resulting residue was alkalized with saturated sodium bicarbonate solution to pH 7 to 8, precipitating a white solid. After filtration and drying, methyl 3-quinolinecarboxylate (3.2 g, 99% yield) was obtained as a white solid; mass spectrometry (M/Z) showed a molecular ion peak of 187.3.

References

[1] Patent: WO2014/33604, 2014, A1. Location in patent: Page/Page column 48
[2] Organic and Biomolecular Chemistry, 2016, vol. 14, # 24, p. 5505 - 5510
[3] Tetrahedron Asymmetry, 2013, vol. 24, # 18, p. 1142 - 1147
[4] Patent: US2016/122303, 2016, A1. Location in patent: Paragraph 0078
[5] Tetrahedron Asymmetry, 2010, vol. 21, # 18, p. 2307 - 2313

methyl quinoline-3-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

methyl quinoline-3-carboxylate Suppliers

China 51 India 1 United Kingdom 1 United States 3 Global 56

Springchem New Material Technology Co.,Limited

Tel: +86-021-62885108 +8613917661608
Email: info@spring-chem.com
Country: China
ProdList: 2068
Advantage: 57

Shanghai Litong Chemical Technology Co.,Ltd.

Tel: 13598610367 0373-7129549
Fax: 0373-8369699
Email: 2468833170@qq.com
Country: China
ProdList: 932
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 42446
Advantage: 60

Shanghai Worldyang Chemical Co.,Ltd.

Tel: 021-021-56795766
Fax: +86-21-56795266
Email: sales@worldyachem.com
Country: China
ProdList: 9476
Advantage: 58

Suzhou yacoo science co.,Ltd

Tel: 0512-87182056 18013166090
Fax: 0512-87182056
Email: lingling.qi@yacoo.com.cn
Country: China
ProdList: 6295
Advantage: 60

Shanghai Tombiopharma Chemical Co. Ltd.

Tel: 13391076197
Email: tombiopharma@163.com
Country: China
ProdList: 4987
Advantage: 55

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

Zhengzhou Guancheng Laboratory equipment Sales

Tel: 0371-88888888 272369594
Fax: QQ:272369594
Email: 2723695949@qq.com
Country: China
ProdList: 4960
Advantage: 50

Shanghai GaoDao Pharmaceutical Co., Ltd.

Tel: 021-15001867143 15001867143
Fax: -
Email: 1095570358@qq.com
Country: China
ProdList: 909
Advantage: 55

SanoChem (Chengdu) Tech. Co., Ltd.

Tel: 28-87999436 02887999436
Fax: QQ:2746983436
Email: sales@sano-chem.com
Country: China
ProdList: 3795
Advantage: 55

More

Less

View Lastest Price from methyl quinoline-3-carboxylate manufacturers

Career Henan Chemical Co

Product: Methyl quinoline-3-carboxylate 53951-84-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98% HPLC
Supply Ability: 10 tons/month
Release date: 2020-01-09

53951-84-1, methyl quinoline-3-carboxylateRelated Search:

C-QUINOLIN-3-YL-METHYLAMINE Quinolin-3-yl-methanol 2-Quinolineacetic acid methyl ester 4-Quinoline-carboxamide 2-Quinolinecarboxaldehyde 4-CYANOQUINOLINE 7-AMinoquinoline Hydrochloride 3-Quinolinecarboxaldehyde 2-QUINOLINYLMETHANOL 3-Quinolinecarboxylic acid 6-Quinolinecarbaldehyde Quinoline-6-boronic acid QUINOLINE-6-SULFONYL CHLORIDE QUINAZOLIN-4-YLAMINE 8-Quinolinesulfonyl chloride QUINOLIN-7-YLBORONIC ACID Quinoline-5-boronic acid Quinoline-5-carboxylic acid

Methyl 3-quinolinecarboxylate

methyl quinoline-3-carboxylate

3-Quinolinecarboxylic acid, methyl ester

Quinoline-3-carboxylic acid methyl ester

Methyl-Quinolone-3-Carboxylate

53951-84-1

API intermediates

Esters

Quinolines, Isoquinolines & Quinoxalines