9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate
- Product Name
- 9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate
- CAS No.
- 206184-49-8
- Chemical Name
- 9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate
- Synonyms
- Tenofovir CRS;Tenofovir(H2O);Unii-99yxe507il;PMPA Monohydrate;Tenofovir (15 mg);Tenofovir (hydrate);R-PMPA of Tenofovir;Tenofovir (1643601);Tenofovir Monohydrate;Tenofovir hydrate (1:1)
- CBNumber
- CB1855342
- Molecular Formula
- C9H16N5O5P
- Formula Weight
- 305.23
- MOL File
- 206184-49-8.mol
9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Property
- Melting point:
- 270-274oC
- storage temp.
- 2-8°C
- solubility
- Aqueous Acid (Slightly), DMSO (Slightly)
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic
Safety
- HS Code
- 2933599550
N-Bromosuccinimide Price
- Product number
- PHR1592
- Product name
- Tenofovir
- Purity
- Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging
- 1G
- Price
- $160
- Updated
- 2022/05/15
- Product number
- 1643601
- Product name
- Tenofovir
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 15MG
- Price
- $400
- Updated
- 2022/05/15
- Product number
- T185533
- Product name
- TenofovirMonohydrate
- Packaging
- 2.5g
- Price
- $145
- Updated
- 2021/12/16
- Product number
- CS-1874
- Product name
- Tenofovir Hydrate
- Purity
- ≥98.0%
- Packaging
- 5mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- B1252
- Product name
- Tenofovir Hydrate
- Packaging
- 50mg
- Price
- $221
- Updated
- 2021/12/16
9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Chemical Properties,Usage,Production
Chemical Properties
WHITE POWDER SOLID
Uses
Tenofovir Monohydrate is an HIV-1 RT inhibitor and antiretroviral drug.
Uses
antineoplastic, thymidylate synthase inhibitor
Definition
ChEBI: A hydrate that is the monohydrate form of anhydrous tenovir.
General Description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Tenofovir is a nucleotide analog reverse transcriptase inhibitor, and is widely used as an antiretroviral agent, for the treatment of HIV infection.
Biological Activity
tenofovir hydrate is an inhibitor of reverse transcriptase used for the treatment of the human immunodeficiency virus 1(hiv-1) and hepatitis b [1].tenofovir hydrate is an antiviral pro-drug and the class of nucleoside reverse transcriptase inhibitor. in addition, tenofovir hydrate has been reported to have a dependent relation between intracellular the drug concentrations and prevent function of hiv-1infection with ec50 values of 29 fmol/106, 40 fmol/106 , 77 fmol/106 and 411 fmol/106 cells for inoculum size 1, 5, 20 and 100 respectively. and the ec90 values of tenofovir hydrate are 267 fmol/106, 348 fmol/106, 640 fmol/106 and 2866 fmol/106 cells for virus inoculums size 1, 5, 20 and 100, respectively [1].
References
[1] duwal s1, schütte c, von kleist m.pharmacokinetics and pharmacodynamics of the reverse transcriptase inhibitor tenofovir and prophylactic efficacy against hiv-1 infection. plos one. 2012;7(7):e40382. doi: 10.1371/journal.pone.0040382. epub 2012 jul 11.
9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Preparation Products And Raw materials
Raw materials
Preparation Products
9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Suppliers
View Lastest Price from 9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate manufacturers
- Product
- 9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate 206184-49-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98% HPLC
- Supply Ability
- 100kg
- Release date
- 2023-07-12
- Product
- 9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate 206184-49-8
- Price
- US $1.00/KG
- Min. Order
- 1G
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-08-15